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The map label for this gene is cbiC [H]

Identifier: 17230036

GI number: 17230036

Start: 3047970

End: 3048590

Strand: Reverse

Name: cbiC [H]

Synonym: all2544

Alternate gene names: 17230036

Gene position: 3048590-3047970 (Counterclockwise)

Preceding gene: 17230037

Following gene: 17230032

Centisome position: 47.53

GC content: 43.8

Gene sequence:

>621_bases
ATGGAATGGCACGTAAGTGATGCTCAAAGTTTAGCAATTATCGATAGTGAAATTGGCGATCATGTGTTCTCGCCAGCAGA
ATATGAAATTGTTCGCCGCGTAATTTACGCTACGGCTGATTTTGAGTACAAGTCTTTAATCAGGTTTTCTGAGCGTGCTT
TACAAGCCGGAGCCGCCGCATTGGCAGCACGGACTACTATTGTGGTAGATGTACCGATGGTGCAAACAGGTATTGCTTAC
GATATTCAAAAAACCTTTGCTAACCCAGTTTTTTGCAGTACAGAAACTTTGACTCGTCCCCAAATAGAAAAAACTCGCGC
CGCATGGGGAATTGAAACTTTAGCCAAACGCTATCCAGAAGGTATTTTTATAGTAGGTCAAGCGCCAACAGCTTTAACTA
CATTAGTCAATTTAATTGAAGCAGAAGAGATTAACCCGGCTTTAATCATTGCTACTCCTGTAGGGTTAGGAGATATAGAA
GATGCCAAAAGGCGCTTGCAAGACTCTTTAGTCCCTAATATCACAATCGACAGCCGCAAAGGTAATGCTGTTGTCGCAGC
TGCGATCGCCGATGGTTTGATAGACTTGGCTTGGCAAGCTTATGGGCAGAAGAGGGAGTGA

Upstream 100 bases:

>100_bases
AGCCTCTAAGCTCTAATCTCTAATCTCTAATCTATCTCCTCTTACTTAGCGATCGCCCAAACTGATAAGCTGAAAGCTAG
TCTCTGAGAATTGAATAGCA

Downstream 100 bases:

>100_bases
TCAATTCAAAATTCAAAATTCAAAATTCAAAATACCCTACGGCTACTCCTGCGGAGAACTCGCAGGGTAGGCTACACCAA
CAAAATTCAAAATAGCCTAC

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MEWHVSDAQSLAIIDSEIGDHVFSPAEYEIVRRVIYATADFEYKSLIRFSERALQAGAAALAARTTIVVDVPMVQTGIAY
DIQKTFANPVFCSTETLTRPQIEKTRAAWGIETLAKRYPEGIFIVGQAPTALTTLVNLIEAEEINPALIIATPVGLGDIE
DAKRRLQDSLVPNITIDSRKGNAVVAAAIADGLIDLAWQAYGQKRE

Sequences:

>Translated_206_residues
MEWHVSDAQSLAIIDSEIGDHVFSPAEYEIVRRVIYATADFEYKSLIRFSERALQAGAAALAARTTIVVDVPMVQTGIAY
DIQKTFANPVFCSTETLTRPQIEKTRAAWGIETLAKRYPEGIFIVGQAPTALTTLVNLIEAEEINPALIIATPVGLGDIE
DAKRRLQDSLVPNITIDSRKGNAVVAAAIADGLIDLAWQAYGQKRE
>Mature_206_residues
MEWHVSDAQSLAIIDSEIGDHVFSPAEYEIVRRVIYATADFEYKSLIRFSERALQAGAAALAARTTIVVDVPMVQTGIAY
DIQKTFANPVFCSTETLTRPQIEKTRAAWGIETLAKRYPEGIFIVGQAPTALTTLVNLIEAEEINPALIIATPVGLGDIE
DAKRRLQDSLVPNITIDSRKGNAVVAAAIADGLIDLAWQAYGQKRE

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22500; Mature: 22500

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWHVSDAQSLAIIDSEIGDHVFSPAEYEIVRRVIYATADFEYKSLIRFSERALQAGAAA
CCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LAARTTIVVDVPMVQTGIAYDIQKTFANPVFCSTETLTRPQIEKTRAAWGIETLAKRYPE
HHHCEEEEEECCHHHHCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCHHHHHHHCCC
GIFIVGQAPTALTTLVNLIEAEEINPALIIATPVGLGDIEDAKRRLQDSLVPNITIDSRK
CEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCC
GNAVVAAAIADGLIDLAWQAYGQKRE
CCEEEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEWHVSDAQSLAIIDSEIGDHVFSPAEYEIVRRVIYATADFEYKSLIRFSERALQAGAAA
CCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LAARTTIVVDVPMVQTGIAYDIQKTFANPVFCSTETLTRPQIEKTRAAWGIETLAKRYPE
HHHCEEEEEECCHHHHCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCHHHHHHHCCC
GIFIVGQAPTALTTLVNLIEAEEINPALIIATPVGLGDIEDAKRRLQDSLVPNITIDSRK
CEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCC
GNAVVAAAIADGLIDLAWQAYGQKRE
CCEEEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]