Click here to switch to the map view.

The map label for this gene is pitB [C]

Identifier: 17229828

GI number: 17229828

Start: 2816367

End: 2817665

Strand: Direct

Name: pitB [C]

Synonym: alr2336

Alternate gene names: 17229828

Gene position: 2816367-2817665 (Clockwise)

Preceding gene: 17229827

Following gene: 17229830

Centisome position: 43.91

GC content: 45.88

Gene sequence:

>1299_bases
ATGGAAATACCAATTACATTACTTTTAGTTGCCCTACTAGCCTTTTATGTAGCTTGGAATCTGGGAGCTAACGATGTCGC
TAATGCAATGGGAACATCTGTCGGTTCCAAAGCTATAACTCTCAAGCAAGCAATAATTATTGCTGGGGTGTTGGAGTTTA
CTGGTGCTGTCTTATTTGGACATGGTGTAACAGAAACCCTGTCCACAAAAGTTGCTAACCCCACATTATTTGCAGCTACT
CCCCAAGTTTTAGTTACTGGCATGATGACAGTATTAATTTCTTGTGGTTTATGGTTGCAAATTGCCACCTCCCGTGGTTT
ACCTGTATCTTCTTCTCATGCAGTTGTAGGTGCGATCGCTGGCTTTAGTTGGGTGGCTTTGGGAGTAAATGCCATTGATT
GGTCATCCATTGGACTAATTACTATCGGTTGGATTTTCACCCCAGTGATTAGTGGAGCGATCGCCGCTTTCTTCTATAGT
CAAATTAAACACTGGATTTTAGAACAACCAAACCAAGTATCCCAACTCAAAGAGTGGATTCCCTGGTTAAGTGCAGTTCT
TCTAGGAGTATTTGGCGTAATTGTCCTCCCTTCCCTAACTCAACCCCTAACCAATGTCTTCATCAACCAATTCGGTGTCA
ACATTCCCCCCCACGATATCCCACTGATCACAGGTGCATTTGCCGCAGTCACACTGACGCTCATAACTTGGCGACAGCTA
GAGGAGGCAGGGGAAAAAATCCCCAGCCAACCGTCAACCGTCAACCGTCAACCGTCAACCGTCAACAATCCCATCGAAAG
CATATTCGCCCGCTTCCAAGTCCTGAGTGCTTGCTTTGTTGCCTTTGCACATGGTTCTAATGATGTGGGTAATGCGATCG
CTCCTTTGGCGGCGATCGTTTATATCAATCAAACTGGTCAAGTCCCTAGTGATGGGATCACTGTTCCCTTGTGGATATTA
GTTCTGGGTGGTGTGGGGATTGTTGGTGGTTTAGCTGTTTGGGGTGAAAAAGTTATTGCCACAATCGGCGAAAACATTAT
TGCTTTACAACCCAGTAGTGGATTTTGTGCGGAACTAGCAACCGCCACCACTATCTTACTTGCATCTCGCATGGGTTTAC
CCGTCTCCACTTCTCATGCCCTTGTGGGTGGTGTAGTTGGTATAGGACTAGTGCAGAGCCTCGATTCAGTTAAATTTCAG
ACTCTCCAGGGTATTGCTACCGCGTGGCTAGTGACAGTGCCTGTAAGCGCAGTTCTGAGCGCTGCCATCTTTAGCATTGC
GCGGATTTTCTTTTTTTAA

Upstream 100 bases:

>100_bases
ATTCTGATTTATCCGAAAATTGGGGATTAGGGACTGGGAACTGGGTATTTTTACCTCTGTCCCATGTCTGTGTTGCTCTA
TCTCTTGCCCCTTTGTCAAT

Downstream 100 bases:

>100_bases
TGGAAAATGTTCTGAAATATGAGTTATGGCTGGGGACTAGGGACTGGGGACTGGGTGAAAAGTTTTGTTGTGTCTAGGTT
GTATCATCTATTGATGTCCT

Product: phosphate permease

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MEIPITLLLVALLAFYVAWNLGANDVANAMGTSVGSKAITLKQAIIIAGVLEFTGAVLFGHGVTETLSTKVANPTLFAAT
PQVLVTGMMTVLISCGLWLQIATSRGLPVSSSHAVVGAIAGFSWVALGVNAIDWSSIGLITIGWIFTPVISGAIAAFFYS
QIKHWILEQPNQVSQLKEWIPWLSAVLLGVFGVIVLPSLTQPLTNVFINQFGVNIPPHDIPLITGAFAAVTLTLITWRQL
EEAGEKIPSQPSTVNRQPSTVNNPIESIFARFQVLSACFVAFAHGSNDVGNAIAPLAAIVYINQTGQVPSDGITVPLWIL
VLGGVGIVGGLAVWGEKVIATIGENIIALQPSSGFCAELATATTILLASRMGLPVSTSHALVGGVVGIGLVQSLDSVKFQ
TLQGIATAWLVTVPVSAVLSAAIFSIARIFFF

Sequences:

>Translated_432_residues
MEIPITLLLVALLAFYVAWNLGANDVANAMGTSVGSKAITLKQAIIIAGVLEFTGAVLFGHGVTETLSTKVANPTLFAAT
PQVLVTGMMTVLISCGLWLQIATSRGLPVSSSHAVVGAIAGFSWVALGVNAIDWSSIGLITIGWIFTPVISGAIAAFFYS
QIKHWILEQPNQVSQLKEWIPWLSAVLLGVFGVIVLPSLTQPLTNVFINQFGVNIPPHDIPLITGAFAAVTLTLITWRQL
EEAGEKIPSQPSTVNRQPSTVNNPIESIFARFQVLSACFVAFAHGSNDVGNAIAPLAAIVYINQTGQVPSDGITVPLWIL
VLGGVGIVGGLAVWGEKVIATIGENIIALQPSSGFCAELATATTILLASRMGLPVSTSHALVGGVVGIGLVQSLDSVKFQ
TLQGIATAWLVTVPVSAVLSAAIFSIARIFFF
>Mature_432_residues
MEIPITLLLVALLAFYVAWNLGANDVANAMGTSVGSKAITLKQAIIIAGVLEFTGAVLFGHGVTETLSTKVANPTLFAAT
PQVLVTGMMTVLISCGLWLQIATSRGLPVSSSHAVVGAIAGFSWVALGVNAIDWSSIGLITIGWIFTPVISGAIAAFFYS
QIKHWILEQPNQVSQLKEWIPWLSAVLLGVFGVIVLPSLTQPLTNVFINQFGVNIPPHDIPLITGAFAAVTLTLITWRQL
EEAGEKIPSQPSTVNRQPSTVNNPIESIFARFQVLSACFVAFAHGSNDVGNAIAPLAAIVYINQTGQVPSDGITVPLWIL
VLGGVGIVGGLAVWGEKVIATIGENIIALQPSSGFCAELATATTILLASRMGLPVSTSHALVGGVVGIGLVQSLDSVKFQ
TLQGIATAWLVTVPVSAVLSAAIFSIARIFFF

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=161, Percent_Identity=49.6894409937888, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI5803173, Length=159, Percent_Identity=49.0566037735849, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI25146401, Length=457, Percent_Identity=34.5733041575492, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71981576, Length=443, Percent_Identity=34.5372460496614, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI32566716, Length=461, Percent_Identity=33.6225596529284, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17536725, Length=462, Percent_Identity=28.1385281385281, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17557328, Length=490, Percent_Identity=27.7551020408163, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539280, Length=165, Percent_Identity=43.030303030303, Blast_Score=140, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6319773, Length=163, Percent_Identity=36.1963190184049, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21356511, Length=157, Percent_Identity=40.7643312101911, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 45241; Mature: 45241

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIPITLLLVALLAFYVAWNLGANDVANAMGTSVGSKAITLKQAIIIAGVLEFTGAVLFG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HGVTETLSTKVANPTLFAATPQVLVTGMMTVLISCGLWLQIATSRGLPVSSSHAVVGAIA
CCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHH
GFSWVALGVNAIDWSSIGLITIGWIFTPVISGAIAAFFYSQIKHWILEQPNQVSQLKEWI
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PWLSAVLLGVFGVIVLPSLTQPLTNVFINQFGVNIPPHDIPLITGAFAAVTLTLITWRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EEAGEKIPSQPSTVNRQPSTVNNPIESIFARFQVLSACFVAFAHGSNDVGNAIAPLAAIV
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YINQTGQVPSDGITVPLWILVLGGVGIVGGLAVWGEKVIATIGENIIALQPSSGFCAELA
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
TATTILLASRMGLPVSTSHALVGGVVGIGLVQSLDSVKFQTLQGIATAWLVTVPVSAVLS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIFSIARIFFF
HHHHHHHHHHCC
>Mature Secondary Structure
MEIPITLLLVALLAFYVAWNLGANDVANAMGTSVGSKAITLKQAIIIAGVLEFTGAVLFG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HGVTETLSTKVANPTLFAATPQVLVTGMMTVLISCGLWLQIATSRGLPVSSSHAVVGAIA
CCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHH
GFSWVALGVNAIDWSSIGLITIGWIFTPVISGAIAAFFYSQIKHWILEQPNQVSQLKEWI
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PWLSAVLLGVFGVIVLPSLTQPLTNVFINQFGVNIPPHDIPLITGAFAAVTLTLITWRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EEAGEKIPSQPSTVNRQPSTVNNPIESIFARFQVLSACFVAFAHGSNDVGNAIAPLAAIV
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YINQTGQVPSDGITVPLWILVLGGVGIVGGLAVWGEKVIATIGENIIALQPSSGFCAELA
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
TATTILLASRMGLPVSTSHALVGGVVGIGLVQSLDSVKFQTLQGIATAWLVTVPVSAVLS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIFSIARIFFF
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]