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The map label for this gene is htpG [H]

Identifier: 17229815

GI number: 17229815

Start: 2799039

End: 2801015

Strand: Direct

Name: htpG [H]

Synonym: alr2323

Alternate gene names: 17229815

Gene position: 2799039-2801015 (Clockwise)

Preceding gene: 17229814

Following gene: 17229816

Centisome position: 43.64

GC content: 43.65

Gene sequence:

>1977_bases
ATGCTAGAGCAAGGCACCATCAGTATTCATACTGAGAATATTTTCCCAATTATCAAGAAATCCCTCTACTCAGACCATCA
AATTTTCCTGCGGGAACTAGTCTCTAACGCTGTAGATGCTATCCAAAAGCTGAAAATGGTATCCCGTGCGGGAGAATATG
CAGGAGTAGTTGATGAACCAGAGATTCAACTCGCCATCGACAAAGATAAAAAAACCCTGTCCATCACCGATAACGGTATC
GGGATGACAGCAGAAGAAGTCAAAAAATATATCAACCAAGTCGCCTTTTCTAGCGCTGAAGAGTTTATTCACAAATATCA
GGGAAAATCAGACCAGCCAATCATCGGTCACTTTGGACTGGGTTTCTATTCCTCCTTCATGGTGGCGCAAAAGGTAGAAA
TTGATACTCTCTCCTATCAAGAAGGAGCGCAAGCAGTCCACTGGAGTTGTGACGGTTCCCCAGAATTTACCCTAGAAGAA
TCATCCCGCACCACCATCGGGACTACCATCACCCTGACTCTGTTACCAGACGAAGAAGAATATTTAGAATCAGCGCGGGT
AAAAAATCTCGTCAAGACTTATTGCGACTTCATGCCAGTACCTATCAAACTGGATGGTGAAGTATTAAACAGACAAAAAG
CACCTTGGCGGGAGTCTCCCAGCAACCTGACAAAAGAAGATTATTTAGAATTTTACCGCTATCTCTATCCTTTCCAAGAA
GAACCCTTACTGTGGGTGCATCTAAACACCGACTATCCCTTTATTATTAACGGGATTCTGTATTTCCCCAAAATGCGTCC
TGATGTGGATGTCACCAAAGGACAAATCAAGTTATTCTGCAACCAAGTTTTCGTCAGTGATAACTGCGAAGAAATTATCC
CCCAGTTCCTTGTACCCATGCGGGGCGTAATCGATAGTACGGATATTCCCCTTAACGTATCACGTAGTGCCTTACAAGGC
GATCGCACCGTCCGCAAAATCGGCGATTATATAGCGAAAAAAGTCGGCGACAGACTCAAAGAACTATACCGCGACGACCG
CGAACAATATATTAGTGCATGGAAAGACTTAAGCACCTTTGTCAAATTCGGTGTCCTCAACGACGAGAAATTTAAAAAGC
AAGTCGAAGACATAATTATTTTCCGCAGTACCGTTAAATGGGAACAACCAGCAGAAACGCCAGCCGTTGAGGTACAGTCC
CAAGAAGGAGATGTTTGGCAAGATATCACCCCTTCCCCCGACTCTCCCACACCAGGCTTACCATACACAACCCTGAAAGA
ATACTTAGAACGCAACAAAGAACGCCACGAAAACCGCGTATTTTACAGCACCGATGAAGCAACCCAAGCCACTTATATAG
AACTACACAAAAACCAAGGCTTAGAAGTTTTATTCCTCGATTCCTTCATCGACACCCACTTTATCAACTTCCTCGAACAG
GAATATCAAGATGTCAAATTTACACGGGTAGATTCTGACCTCGATAATACCTTGCTCGAACAAGACAAAGCCGGGGAAAT
TGTTGACCCCACCACAAATAAAACCAAGAGTGAGATCATTAAAGAGTTATTTGAGAAATCCCTCAATAAACCTAAAGTCA
ACATCCGCACTGAAGCACTCAAGTCTGATGATCCTCAAGGTACACCACCGGCGATCGTTCTCTTACCAGAATTTCTCCGC
CGCATGAGGGAAATGACCGCCATGATGCAGCAGCAAAACGCAGATTTTCCCGAAGACCACATTTTACTAGTGAATACAGC
CCATCCCCTAATTCAAAACTTGGTAAACCTCAACCAAGGTGCAATTATTCAAGGCGATGGAGAATCAACCACAAATCCCT
TAGTCAACTTAATTTGTCAACACGTTTACGATTTAGCGTTAATGTCCCAGAAAGGTTTCGACGCAGAAGGAATGAAATCT
TTTGTCGAACGTTCCAACGACGTATTAACCAAGCTGACCCAACAAGCCAAAAATTAG

Upstream 100 bases:

>100_bases
TTAGTCCCATGCTCTTTTATATCTTGGGCATCTACCCATGATCATAAAAAGCTAAGATGTCTTGACTAAACAAATAGTTT
CAGATACTAAAATCAAAATC

Downstream 100 bases:

>100_bases
CAACCCATCTTGTAAGCAGTACTGCTAGGCTGTTTTAACGTGAGTCTCCAACAGAGGAACACCTACGGGAAGAGCGAAAG
AAAACTTTCTGTTTTCTTAA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MLEQGTISIHTENIFPIIKKSLYSDHQIFLRELVSNAVDAIQKLKMVSRAGEYAGVVDEPEIQLAIDKDKKTLSITDNGI
GMTAEEVKKYINQVAFSSAEEFIHKYQGKSDQPIIGHFGLGFYSSFMVAQKVEIDTLSYQEGAQAVHWSCDGSPEFTLEE
SSRTTIGTTITLTLLPDEEEYLESARVKNLVKTYCDFMPVPIKLDGEVLNRQKAPWRESPSNLTKEDYLEFYRYLYPFQE
EPLLWVHLNTDYPFIINGILYFPKMRPDVDVTKGQIKLFCNQVFVSDNCEEIIPQFLVPMRGVIDSTDIPLNVSRSALQG
DRTVRKIGDYIAKKVGDRLKELYRDDREQYISAWKDLSTFVKFGVLNDEKFKKQVEDIIIFRSTVKWEQPAETPAVEVQS
QEGDVWQDITPSPDSPTPGLPYTTLKEYLERNKERHENRVFYSTDEATQATYIELHKNQGLEVLFLDSFIDTHFINFLEQ
EYQDVKFTRVDSDLDNTLLEQDKAGEIVDPTTNKTKSEIIKELFEKSLNKPKVNIRTEALKSDDPQGTPPAIVLLPEFLR
RMREMTAMMQQQNADFPEDHILLVNTAHPLIQNLVNLNQGAIIQGDGESTTNPLVNLICQHVYDLALMSQKGFDAEGMKS
FVERSNDVLTKLTQQAKN

Sequences:

>Translated_658_residues
MLEQGTISIHTENIFPIIKKSLYSDHQIFLRELVSNAVDAIQKLKMVSRAGEYAGVVDEPEIQLAIDKDKKTLSITDNGI
GMTAEEVKKYINQVAFSSAEEFIHKYQGKSDQPIIGHFGLGFYSSFMVAQKVEIDTLSYQEGAQAVHWSCDGSPEFTLEE
SSRTTIGTTITLTLLPDEEEYLESARVKNLVKTYCDFMPVPIKLDGEVLNRQKAPWRESPSNLTKEDYLEFYRYLYPFQE
EPLLWVHLNTDYPFIINGILYFPKMRPDVDVTKGQIKLFCNQVFVSDNCEEIIPQFLVPMRGVIDSTDIPLNVSRSALQG
DRTVRKIGDYIAKKVGDRLKELYRDDREQYISAWKDLSTFVKFGVLNDEKFKKQVEDIIIFRSTVKWEQPAETPAVEVQS
QEGDVWQDITPSPDSPTPGLPYTTLKEYLERNKERHENRVFYSTDEATQATYIELHKNQGLEVLFLDSFIDTHFINFLEQ
EYQDVKFTRVDSDLDNTLLEQDKAGEIVDPTTNKTKSEIIKELFEKSLNKPKVNIRTEALKSDDPQGTPPAIVLLPEFLR
RMREMTAMMQQQNADFPEDHILLVNTAHPLIQNLVNLNQGAIIQGDGESTTNPLVNLICQHVYDLALMSQKGFDAEGMKS
FVERSNDVLTKLTQQAKN
>Mature_658_residues
MLEQGTISIHTENIFPIIKKSLYSDHQIFLRELVSNAVDAIQKLKMVSRAGEYAGVVDEPEIQLAIDKDKKTLSITDNGI
GMTAEEVKKYINQVAFSSAEEFIHKYQGKSDQPIIGHFGLGFYSSFMVAQKVEIDTLSYQEGAQAVHWSCDGSPEFTLEE
SSRTTIGTTITLTLLPDEEEYLESARVKNLVKTYCDFMPVPIKLDGEVLNRQKAPWRESPSNLTKEDYLEFYRYLYPFQE
EPLLWVHLNTDYPFIINGILYFPKMRPDVDVTKGQIKLFCNQVFVSDNCEEIIPQFLVPMRGVIDSTDIPLNVSRSALQG
DRTVRKIGDYIAKKVGDRLKELYRDDREQYISAWKDLSTFVKFGVLNDEKFKKQVEDIIIFRSTVKWEQPAETPAVEVQS
QEGDVWQDITPSPDSPTPGLPYTTLKEYLERNKERHENRVFYSTDEATQATYIELHKNQGLEVLFLDSFIDTHFINFLEQ
EYQDVKFTRVDSDLDNTLLEQDKAGEIVDPTTNKTKSEIIKELFEKSLNKPKVNIRTEALKSDDPQGTPPAIVLLPEFLR
RMREMTAMMQQQNADFPEDHILLVNTAHPLIQNLVNLNQGAIIQGDGESTTNPLVNLICQHVYDLALMSQKGFDAEGMKS
FVERSNDVLTKLTQQAKN

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=681, Percent_Identity=28.3406754772394, Blast_Score=252, Evalue=1e-66,
Organism=Homo sapiens, GI4507677, Length=661, Percent_Identity=26.6263237518911, Blast_Score=207, Evalue=4e-53,
Organism=Homo sapiens, GI154146191, Length=285, Percent_Identity=27.3684210526316, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI153792590, Length=285, Percent_Identity=28.0701754385965, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI20149594, Length=285, Percent_Identity=27.719298245614, Blast_Score=116, Evalue=8e-26,
Organism=Escherichia coli, GI1786679, Length=523, Percent_Identity=31.7399617590822, Blast_Score=248, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI115535205, Length=476, Percent_Identity=30.4621848739496, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI115535167, Length=393, Percent_Identity=32.3155216284987, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17542208, Length=581, Percent_Identity=29.0877796901893, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17559162, Length=543, Percent_Identity=26.7034990791897, Blast_Score=201, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323840, Length=564, Percent_Identity=26.241134751773, Blast_Score=190, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6325016, Length=196, Percent_Identity=34.1836734693878, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24586016, Length=391, Percent_Identity=35.5498721227622, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI21357739, Length=672, Percent_Identity=26.0416666666667, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17647529, Length=292, Percent_Identity=27.3972602739726, Blast_Score=122, Evalue=7e-28,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 75313; Mature: 75313

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQGTISIHTENIFPIIKKSLYSDHQIFLRELVSNAVDAIQKLKMVSRAGEYAGVVDEP
CCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EIQLAIDKDKKTLSITDNGIGMTAEEVKKYINQVAFSSAEEFIHKYQGKSDQPIIGHFGL
CEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHH
GFYSSFMVAQKVEIDTLSYQEGAQAVHWSCDGSPEFTLEESSRTTIGTTITLTLLPDEEE
HHHHHHHHHHHEEECCCCHHCCCCEEEEECCCCCCEEEECCCCEEEEEEEEEEECCCHHH
YLESARVKNLVKTYCDFMPVPIKLDGEVLNRQKAPWRESPSNLTKEDYLEFYRYLYPFQE
HHHHHHHHHHHHHHHCCCCCCEEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
EPLLWVHLNTDYPFIINGILYFPKMRPDVDVTKGQIKLFCNQVFVSDNCEEIIPQFLVPM
CCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
RGVIDSTDIPLNVSRSALQGDRTVRKIGDYIAKKVGDRLKELYRDDREQYISAWKDLSTF
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKFGVLNDEKFKKQVEDIIIFRSTVKWEQPAETPAVEVQSQEGDVWQDITPSPDSPTPGL
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
PYTTLKEYLERNKERHENRVFYSTDEATQATYIELHKNQGLEVLFLDSFIDTHFINFLEQ
CHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHH
EYQDVKFTRVDSDLDNTLLEQDKAGEIVDPTTNKTKSEIIKELFEKSLNKPKVNIRTEAL
HHHCCEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHH
KSDDPQGTPPAIVLLPEFLRRMREMTAMMQQQNADFPEDHILLVNTAHPLIQNLVNLNQG
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHCCCCC
AIIQGDGESTTNPLVNLICQHVYDLALMSQKGFDAEGMKSFVERSNDVLTKLTQQAKN
CEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEQGTISIHTENIFPIIKKSLYSDHQIFLRELVSNAVDAIQKLKMVSRAGEYAGVVDEP
CCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EIQLAIDKDKKTLSITDNGIGMTAEEVKKYINQVAFSSAEEFIHKYQGKSDQPIIGHFGL
CEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHH
GFYSSFMVAQKVEIDTLSYQEGAQAVHWSCDGSPEFTLEESSRTTIGTTITLTLLPDEEE
HHHHHHHHHHHEEECCCCHHCCCCEEEEECCCCCCEEEECCCCEEEEEEEEEEECCCHHH
YLESARVKNLVKTYCDFMPVPIKLDGEVLNRQKAPWRESPSNLTKEDYLEFYRYLYPFQE
HHHHHHHHHHHHHHHCCCCCCEEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
EPLLWVHLNTDYPFIINGILYFPKMRPDVDVTKGQIKLFCNQVFVSDNCEEIIPQFLVPM
CCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
RGVIDSTDIPLNVSRSALQGDRTVRKIGDYIAKKVGDRLKELYRDDREQYISAWKDLSTF
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKFGVLNDEKFKKQVEDIIIFRSTVKWEQPAETPAVEVQSQEGDVWQDITPSPDSPTPGL
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
PYTTLKEYLERNKERHENRVFYSTDEATQATYIELHKNQGLEVLFLDSFIDTHFINFLEQ
CHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHH
EYQDVKFTRVDSDLDNTLLEQDKAGEIVDPTTNKTKSEIIKELFEKSLNKPKVNIRTEAL
HHHCCEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHH
KSDDPQGTPPAIVLLPEFLRRMREMTAMMQQQNADFPEDHILLVNTAHPLIQNLVNLNQG
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHCCCCC
AIIQGDGESTTNPLVNLICQHVYDLALMSQKGFDAEGMKSFVERSNDVLTKLTQQAKN
CEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]