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The map label for this gene is gacS [H]

Identifier: 17229771

GI number: 17229771

Start: 2742247

End: 2746146

Strand: Direct

Name: gacS [H]

Synonym: alr2279

Alternate gene names: 17229771

Gene position: 2742247-2746146 (Clockwise)

Preceding gene: 17229770

Following gene: 17229772

Centisome position: 42.76

GC content: 43.05

Gene sequence:

>3900_bases
ATGACGACTGATAGGGATAGTAGCTCCAAAAAATTTGGTCTTTCTCCCGAACAATTTGCTGCTTTGTTCCCCTTCCATCT
GGTTATAGATCGAGAATTAAAGATTGTTCAGGCGGGTGAGGTAATTCAGCGTATTTTGGAGCCTATGGTGCTTCTTGATA
GTTATTTGGGAGAGCATTTTCAAATCAGTCGCCCCAAATGCCTAACTAGCTTTGAAGGGATTTGCCAACAAACGCGATCG
CTTTTCATTCTACAAGCCCACTATCAGGAAATACAGCTAAAGGGACAAATGTTAAATTTAGAGTCCCGCGATCATCTGCT
ATTTCTTGGTTCTCCTTGGATTACTGATATCGCTGATTTAAAAAATCTGGGATTGAAGATCAATGATTTCCCTCTACATG
ACTCTGTTTCCGATTATTTGTTTCTGTTACAGGCTAAAAATTCTGCCCTTGCTGATGCTCAAAAACTGACTACAAAACTC
AAAGACCAAAAGACTGAATTACAAACAACAGCCTTACGACTGAGGACACTAATTGAGAGTTTACAGTCTGGCATTCTCCT
GGAAGATGCAAACCAGCATATTATTCTAGTAAATCAAGAATTTTGTGATTACTTTCGCATTCCTCTACCTCCACAAGCTT
TGCAAGGTATGGATTGTCAGCAAGCTTTGGAAGCGAGTAAACATCTATTCACTGAACCAGAGAGATTTATTTGCACCACA
GATGAGATCATCCGTCAAGGCAAAATGTTTCTCCATCAAGAATGGGAACTTCAAGATGGACGCACCTTAGAGCAAAACTA
TATACCGATTGTGGTTGATCATAAACTTTATGGTCATCTGTGGAAATATCGTGACATTACCCAATACAAAAAATCAGAAG
TTGCTTTGAGGTTAAGTGAGGAACGATTAAAGCTGGCTGTAGATGCTGTAGAAGAAGGTCTATGGGACTGGAATCTAGTC
ACGGGAGAAGTTTATCGTAGCGCACGTTGGTTTACCATGTTGGGTTACACCCCTATGGAAATTGGCAACGATATTAAATT
CAGAGATAAGTTGATCCATCCAGATGATATCCCCTTGATGCAGCAAAGGCTGATATCCCACCTCAAAGGTGATACTCCTT
TCTATGAAGTAGAAATACGTTTACTCGCTAAATCTGGAGAATGGAGGTGGATTCTCGACCGGGGTAAATTAGTGAGTCGG
GATTCTCAGGGTAGAGCTATCAGAATGGTGGGAACTCATTTAGATATTACCCAACGGAAACAGGCAGAACAAGACCTACA
GCAGCAATATCAACACACTTTACTGCTGAAACAAATCACAGAAGAAATCCGCCAGTCCTTACAATGGGAAAAAATTCTCA
AGACAACAGTTACAGAAGTTCAGCGAATTTTACAAGTTGATCGCGCCCTGATTTTCCAAATCAATTCTGATGGTTCTGGC
AAAGTGGTTCAAGAGGCGGTAATGCCTGGATGGTCAGTCACTTTAGACCAAGATATTTATGATCCCTGCCTCAAAGATGG
ATACCTTAATATGTATCGGGATGGACGCATTACTGCCATTGCTGATGTGTATCAAGGGGGTTTGAAACCTTGCTATGTAG
AATTCTTGCAACAGTTCCAGGTCAAAGCTAATTTGGTTGTACCAATTCGAGTGCGACGAAATTTGTGGGGGTTATTAATT
GTCCATCAGTGCGATCGCCCCAGGCAATGGACGGAATTAGAATTGGATCTCCTCAAACATCTGGCAGATCAAATGGGTAT
TGCCCTCACCCAATCCCAATTATTGGCTCAGGAAACTAGGCAAGCCCAATTATTAGCGCTGCAAAATGAAGAACTGAACG
TTGCTAAACAAGTAGCAGAGAAGGCAAATATGGCTAAGAGTAATTTCCTGGCCACCATGAGCCATGAAATTCGTACTCCG
ATGAATGCCATCATTGGTATGAGTGGACTGCTCCTAGATACTACCCTCAAACCTGAGCAATTCGACTATGTAGAAACTAT
TCGCAACAGCAGTCACACATTATTAACAATCATTAATGACATCCTCGACTTTTCTAAAATTGAGTCTGGCAAATTAGAAC
TAGAAGAACAACCTTTTGATTTACGCCTTTGTGTGGAAGAAGCCTTAGATTTACTGGCTCCTCAAGCAGCCTCAAAAGGC
ATCGAACTCATGTACCAACTAGAACCAGACACACCCACTTTAGTTGTGGGTGACATTACTCGTATCAGGCAAATTCTGTG
GAATTTGGTCAGTAATGCGGTCAAGTTTACCAAAATTGGCGAAATATGTATCACTATTGGGGCAAAACAGAAGATTTATA
AACAGACAGACCCTACTCGCTACGAATTTCAATTTGCAGTCCAAGATACGGGTATTGGCATAGAACGCGATCGCCTACAT
CGATTATTCAAACCTTTTAGTCAAGTCGATGCCTCCATGACTAGACGCTATGGTGGTACAGGCCTGGGACTGGCAATCAG
TAAGCGCCTGAGTGAAATCATGGGCGGCAAAATGTGGGTAGAAAGTCAATCGCATCAAGGCTCTATTTTCTATTTCACTG
CTACCTTACAGGTCAATTCCTCTGCCATCAATAGCGCCGCCAAGGTCGATCCAGAATTGGTTGGCAAACGATTACTGCTA
GCAGTCGGTAACGCCAACTTGAGAAAATGCTTAACCCGGCAACTCCAGTCCTTAGGATTAGATGTCCAGGCTGTAGATTC
CAACGCGACGGCGCTACATTGTCTATGGCAACATACTTCCCTAGCTCTAGCTGTGTTAGATGTTGATAGCCCACAGATCA
ACGGCCTCCACCTCAGTACAAAAATCCGTGCTATTCCCCAGCATCAGAATTTACCTCTGGTGATGTTGAGTGCTAAAGGC
AAACAAACTTTAGAAGTGAAGCAAGTAGCATCGGAATTTACGGCTTTTCTACATAAACCCCTGCGCCATTACCAGTTACA
CAATACACTTTTGCAAATTGTACGTGGTAAGTGGTTGAGCAAATCCACCCCTCAAGGCATAATTCCCTCTTACTCCCGCT
TACCTAAACCCAATCTCCCAGCTATTGATACCCATCTGGCGGAAAATTTGCCGCTCAAAATTCTTCTAGTTGAAGACGTG
TTGGTGAATCAGAAAATTGCGATGAATATGCTGCATCTGTTGGGATATCGTACCGATGTCGCTAACAATGGCTTAGAAGC
TCTGGAAGCGCTACAAAGACAACTCTATGATGTTGTGTTTATGGATATTCAGATGCCGGAAATGGATGGCTGGGAAACCA
CCCACAAAATTCGCCAGGAATTTTCCCCTACTCTTCAACCTTGGATCATTGCCATGACTGCCCACGCCCGCCCAGAAGAT
CGTCAGCAGTGCTTGGCAGCAGGTATGGATGACTACATAAGTAAGCCGATCAGCCTAGAAGATATCACCACAGCTTTGAA
AAAGTTCGGTAGTCAGCGTCAACCAGCATTAGAGTCTCCCGCATCGGTGTCTATATCTGCCCCACCTGCACCTACCCCAC
AACCCAAAATAGAAGAGGTAATTGACCAACAGACTTTAGAATACCTGCGAAATTTAGGTGGTAGCGACGAAGCAGATGAG
GATGGAGGCGGTAGTAGTATCATCACTGAGTTAATCCAACTTTACCTAGAAGATACCCCAGCCAAAATTCAGGCAATTCA
AGATGCAGCAACCTTGGAAGACCGTTCACAGTTAGCCAGAATAGCTCACGCTTTGCGATCGCCTAGTGTGAGTATTGGAG
CTATTAACCTGGGAAAAATCTGTGAAACCGTGGAGGATGAAGCCAAGGAACAATCAATGGATCAACTTACTGCTTTGGTT
AATCAACTCAACAACGAATATCAAAATGTTGTAGCGGCACTTAAAACCCTTATTTTTTAA

Upstream 100 bases:

>100_bases
AAACGCTTTCAGACAAAAGTTGAAGTTACTCAAACCGCTTTTCGTGAGACTGGTGAGGATCACGATATCTTCTCTATTAA
ATACGAAGACTCGAATTTAT

Downstream 100 bases:

>100_bases
AATAAATAGCATTTTTCTCTTAGCTCAAATTAAAAAAATATGAAAGAAAATACATTTTCCTCAGTCCCCAATCTGAATTA
CCCCTCATCCTCAGAATGGT

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1299; Mature: 1298

Protein sequence:

>1299_residues
MTTDRDSSSKKFGLSPEQFAALFPFHLVIDRELKIVQAGEVIQRILEPMVLLDSYLGEHFQISRPKCLTSFEGICQQTRS
LFILQAHYQEIQLKGQMLNLESRDHLLFLGSPWITDIADLKNLGLKINDFPLHDSVSDYLFLLQAKNSALADAQKLTTKL
KDQKTELQTTALRLRTLIESLQSGILLEDANQHIILVNQEFCDYFRIPLPPQALQGMDCQQALEASKHLFTEPERFICTT
DEIIRQGKMFLHQEWELQDGRTLEQNYIPIVVDHKLYGHLWKYRDITQYKKSEVALRLSEERLKLAVDAVEEGLWDWNLV
TGEVYRSARWFTMLGYTPMEIGNDIKFRDKLIHPDDIPLMQQRLISHLKGDTPFYEVEIRLLAKSGEWRWILDRGKLVSR
DSQGRAIRMVGTHLDITQRKQAEQDLQQQYQHTLLLKQITEEIRQSLQWEKILKTTVTEVQRILQVDRALIFQINSDGSG
KVVQEAVMPGWSVTLDQDIYDPCLKDGYLNMYRDGRITAIADVYQGGLKPCYVEFLQQFQVKANLVVPIRVRRNLWGLLI
VHQCDRPRQWTELELDLLKHLADQMGIALTQSQLLAQETRQAQLLALQNEELNVAKQVAEKANMAKSNFLATMSHEIRTP
MNAIIGMSGLLLDTTLKPEQFDYVETIRNSSHTLLTIINDILDFSKIESGKLELEEQPFDLRLCVEEALDLLAPQAASKG
IELMYQLEPDTPTLVVGDITRIRQILWNLVSNAVKFTKIGEICITIGAKQKIYKQTDPTRYEFQFAVQDTGIGIERDRLH
RLFKPFSQVDASMTRRYGGTGLGLAISKRLSEIMGGKMWVESQSHQGSIFYFTATLQVNSSAINSAAKVDPELVGKRLLL
AVGNANLRKCLTRQLQSLGLDVQAVDSNATALHCLWQHTSLALAVLDVDSPQINGLHLSTKIRAIPQHQNLPLVMLSAKG
KQTLEVKQVASEFTAFLHKPLRHYQLHNTLLQIVRGKWLSKSTPQGIIPSYSRLPKPNLPAIDTHLAENLPLKILLVEDV
LVNQKIAMNMLHLLGYRTDVANNGLEALEALQRQLYDVVFMDIQMPEMDGWETTHKIRQEFSPTLQPWIIAMTAHARPED
RQQCLAAGMDDYISKPISLEDITTALKKFGSQRQPALESPASVSISAPPAPTPQPKIEEVIDQQTLEYLRNLGGSDEADE
DGGGSSIITELIQLYLEDTPAKIQAIQDAATLEDRSQLARIAHALRSPSVSIGAINLGKICETVEDEAKEQSMDQLTALV
NQLNNEYQNVVAALKTLIF

Sequences:

>Translated_1299_residues
MTTDRDSSSKKFGLSPEQFAALFPFHLVIDRELKIVQAGEVIQRILEPMVLLDSYLGEHFQISRPKCLTSFEGICQQTRS
LFILQAHYQEIQLKGQMLNLESRDHLLFLGSPWITDIADLKNLGLKINDFPLHDSVSDYLFLLQAKNSALADAQKLTTKL
KDQKTELQTTALRLRTLIESLQSGILLEDANQHIILVNQEFCDYFRIPLPPQALQGMDCQQALEASKHLFTEPERFICTT
DEIIRQGKMFLHQEWELQDGRTLEQNYIPIVVDHKLYGHLWKYRDITQYKKSEVALRLSEERLKLAVDAVEEGLWDWNLV
TGEVYRSARWFTMLGYTPMEIGNDIKFRDKLIHPDDIPLMQQRLISHLKGDTPFYEVEIRLLAKSGEWRWILDRGKLVSR
DSQGRAIRMVGTHLDITQRKQAEQDLQQQYQHTLLLKQITEEIRQSLQWEKILKTTVTEVQRILQVDRALIFQINSDGSG
KVVQEAVMPGWSVTLDQDIYDPCLKDGYLNMYRDGRITAIADVYQGGLKPCYVEFLQQFQVKANLVVPIRVRRNLWGLLI
VHQCDRPRQWTELELDLLKHLADQMGIALTQSQLLAQETRQAQLLALQNEELNVAKQVAEKANMAKSNFLATMSHEIRTP
MNAIIGMSGLLLDTTLKPEQFDYVETIRNSSHTLLTIINDILDFSKIESGKLELEEQPFDLRLCVEEALDLLAPQAASKG
IELMYQLEPDTPTLVVGDITRIRQILWNLVSNAVKFTKIGEICITIGAKQKIYKQTDPTRYEFQFAVQDTGIGIERDRLH
RLFKPFSQVDASMTRRYGGTGLGLAISKRLSEIMGGKMWVESQSHQGSIFYFTATLQVNSSAINSAAKVDPELVGKRLLL
AVGNANLRKCLTRQLQSLGLDVQAVDSNATALHCLWQHTSLALAVLDVDSPQINGLHLSTKIRAIPQHQNLPLVMLSAKG
KQTLEVKQVASEFTAFLHKPLRHYQLHNTLLQIVRGKWLSKSTPQGIIPSYSRLPKPNLPAIDTHLAENLPLKILLVEDV
LVNQKIAMNMLHLLGYRTDVANNGLEALEALQRQLYDVVFMDIQMPEMDGWETTHKIRQEFSPTLQPWIIAMTAHARPED
RQQCLAAGMDDYISKPISLEDITTALKKFGSQRQPALESPASVSISAPPAPTPQPKIEEVIDQQTLEYLRNLGGSDEADE
DGGGSSIITELIQLYLEDTPAKIQAIQDAATLEDRSQLARIAHALRSPSVSIGAINLGKICETVEDEAKEQSMDQLTALV
NQLNNEYQNVVAALKTLIF
>Mature_1298_residues
TTDRDSSSKKFGLSPEQFAALFPFHLVIDRELKIVQAGEVIQRILEPMVLLDSYLGEHFQISRPKCLTSFEGICQQTRSL
FILQAHYQEIQLKGQMLNLESRDHLLFLGSPWITDIADLKNLGLKINDFPLHDSVSDYLFLLQAKNSALADAQKLTTKLK
DQKTELQTTALRLRTLIESLQSGILLEDANQHIILVNQEFCDYFRIPLPPQALQGMDCQQALEASKHLFTEPERFICTTD
EIIRQGKMFLHQEWELQDGRTLEQNYIPIVVDHKLYGHLWKYRDITQYKKSEVALRLSEERLKLAVDAVEEGLWDWNLVT
GEVYRSARWFTMLGYTPMEIGNDIKFRDKLIHPDDIPLMQQRLISHLKGDTPFYEVEIRLLAKSGEWRWILDRGKLVSRD
SQGRAIRMVGTHLDITQRKQAEQDLQQQYQHTLLLKQITEEIRQSLQWEKILKTTVTEVQRILQVDRALIFQINSDGSGK
VVQEAVMPGWSVTLDQDIYDPCLKDGYLNMYRDGRITAIADVYQGGLKPCYVEFLQQFQVKANLVVPIRVRRNLWGLLIV
HQCDRPRQWTELELDLLKHLADQMGIALTQSQLLAQETRQAQLLALQNEELNVAKQVAEKANMAKSNFLATMSHEIRTPM
NAIIGMSGLLLDTTLKPEQFDYVETIRNSSHTLLTIINDILDFSKIESGKLELEEQPFDLRLCVEEALDLLAPQAASKGI
ELMYQLEPDTPTLVVGDITRIRQILWNLVSNAVKFTKIGEICITIGAKQKIYKQTDPTRYEFQFAVQDTGIGIERDRLHR
LFKPFSQVDASMTRRYGGTGLGLAISKRLSEIMGGKMWVESQSHQGSIFYFTATLQVNSSAINSAAKVDPELVGKRLLLA
VGNANLRKCLTRQLQSLGLDVQAVDSNATALHCLWQHTSLALAVLDVDSPQINGLHLSTKIRAIPQHQNLPLVMLSAKGK
QTLEVKQVASEFTAFLHKPLRHYQLHNTLLQIVRGKWLSKSTPQGIIPSYSRLPKPNLPAIDTHLAENLPLKILLVEDVL
VNQKIAMNMLHLLGYRTDVANNGLEALEALQRQLYDVVFMDIQMPEMDGWETTHKIRQEFSPTLQPWIIAMTAHARPEDR
QQCLAAGMDDYISKPISLEDITTALKKFGSQRQPALESPASVSISAPPAPTPQPKIEEVIDQQTLEYLRNLGGSDEADED
GGGSSIITELIQLYLEDTPAKIQAIQDAATLEDRSQLARIAHALRSPSVSIGAINLGKICETVEDEAKEQSMDQLTALVN
QLNNEYQNVVAALKTLIF

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI4504215, Length=176, Percent_Identity=31.25, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI194595482, Length=134, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI194595474, Length=134, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI194595476, Length=134, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI194595472, Length=134, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI67763816, Length=134, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI194595478, Length=134, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI4504211, Length=157, Percent_Identity=27.3885350318471, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=765, Percent_Identity=31.1111111111111, Blast_Score=293, Evalue=5e-80,
Organism=Escherichia coli, GI145693157, Length=552, Percent_Identity=33.8768115942029, Blast_Score=245, Evalue=1e-65,
Organism=Escherichia coli, GI87081816, Length=420, Percent_Identity=35, Blast_Score=202, Evalue=8e-53,
Organism=Escherichia coli, GI48994928, Length=344, Percent_Identity=37.2093023255814, Blast_Score=199, Evalue=1e-51,
Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=34.4, Blast_Score=156, Evalue=1e-38,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=30.0411522633745, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=28.6290322580645, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=27.1929824561404, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=27.5720164609054, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=26.1603375527426, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=34.1880341880342, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=26.5486725663717, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=35.3448275862069, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=26.4069264069264, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=143, Percent_Identity=34.965034965035, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322000, Length=127, Percent_Identity=33.8582677165354, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651577, Length=180, Percent_Identity=31.6666666666667, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24651096, Length=147, Percent_Identity=27.2108843537415, Blast_Score=73, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 147254; Mature: 147123

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDRDSSSKKFGLSPEQFAALFPFHLVIDRELKIVQAGEVIQRILEPMVLLDSYLGEHF
CCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCHHEEHHHHHHHHHHHHHHHHHHHCCCCE
QISRPKCLTSFEGICQQTRSLFILQAHYQEIQLKGQMLNLESRDHLLFLGSPWITDIADL
ECCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCEECCCCCCCEEEECCCCHHHHHHH
KNLGLKINDFPLHDSVSDYLFLLQAKNSALADAQKLTTKLKDQKTELQTTALRLRTLIES
HHCCCEEECCCCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSGILLEDANQHIILVNQEFCDYFRIPLPPQALQGMDCQQALEASKHLFTEPERFICTT
HHCCCEEECCCCEEEEEEHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEECH
DEIIRQGKMFLHQEWELQDGRTLEQNYIPIVVDHKLYGHLWKYRDITQYKKSEVALRLSE
HHHHHCCHHHHHCCCCCCCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHEEEHH
ERLKLAVDAVEEGLWDWNLVTGEVYRSARWFTMLGYTPMEIGNDIKFRDKLIHPDDIPLM
HHHHHHHHHHHCCCCCCEEEEHHHHHHHCEEEEECCCHHHCCCCCCHHHCCCCCCCCHHH
QQRLISHLKGDTPFYEVEIRLLAKSGEWRWILDRGKLVSRDSQGRAIRMVGTHLDITQRK
HHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEECCCEECCCCCCCEEEEEECCCCHHHHH
QAEQDLQQQYQHTLLLKQITEEIRQSLQWEKILKTTVTEVQRILQVDRALIFQINSDGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
KVVQEAVMPGWSVTLDQDIYDPCLKDGYLNMYRDGRITAIADVYQGGLKPCYVEFLQQFQ
HHHHHHHCCCCEEEECCHHHHHHHHCCCCEEECCCCEEEEHHHHHCCCCHHHHHHHHHHH
VKANLVVPIRVRRNLWGLLIVHQCDRPRQWTELELDLLKHLADQMGIALTQSQLLAQETR
HHCCEEEEEEECCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QAQLLALQNEELNVAKQVAEKANMAKSNFLATMSHEIRTPMNAIIGMSGLLLDTTLKPEQ
HHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEECCCCCCH
FDYVETIRNSSHTLLTIINDILDFSKIESGKLELEEQPFDLRLCVEEALDLLAPQAASKG
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHCCC
IELMYQLEPDTPTLVVGDITRIRQILWNLVSNAVKFTKIGEICITIGAKQKIYKQTDPTR
CEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHCCCCCE
YEFQFAVQDTGIGIERDRLHRLFKPFSQVDASMTRRYGGTGLGLAISKRLSEIMGGKMWV
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
ESQSHQGSIFYFTATLQVNSSAINSAAKVDPELVGKRLLLAVGNANLRKCLTRQLQSLGL
ECCCCCCEEEEEEEEEEECHHHHHHHHCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCC
DVQAVDSNATALHCLWQHTSLALAVLDVDSPQINGLHLSTKIRAIPQHQNLPLVMLSAKG
CEEEECCCCCEEEEEHHCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCEEEEECCC
KQTLEVKQVASEFTAFLHKPLRHYQLHNTLLQIVRGKWLSKSTPQGIIPSYSRLPKPNLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCC
AIDTHLAENLPLKILLVEDVLVNQKIAMNMLHLLGYRTDVANNGLEALEALQRQLYDVVF
CHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MDIQMPEMDGWETTHKIRQEFSPTLQPWIIAMTAHARPEDRQQCLAAGMDDYISKPISLE
EEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHH
DITTALKKFGSQRQPALESPASVSISAPPAPTPQPKIEEVIDQQTLEYLRNLGGSDEADE
HHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DGGGSSIITELIQLYLEDTPAKIQAIQDAATLEDRSQLARIAHALRSPSVSIGAINLGKI
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEHHHH
CETVEDEAKEQSMDQLTALVNQLNNEYQNVVAALKTLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTDRDSSSKKFGLSPEQFAALFPFHLVIDRELKIVQAGEVIQRILEPMVLLDSYLGEHF
CCCCCCCCCCCCCCHHHHHHHHHHHEEEECCHHEEHHHHHHHHHHHHHHHHHHHCCCCE
QISRPKCLTSFEGICQQTRSLFILQAHYQEIQLKGQMLNLESRDHLLFLGSPWITDIADL
ECCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCEECCCCCCCEEEECCCCHHHHHHH
KNLGLKINDFPLHDSVSDYLFLLQAKNSALADAQKLTTKLKDQKTELQTTALRLRTLIES
HHCCCEEECCCCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSGILLEDANQHIILVNQEFCDYFRIPLPPQALQGMDCQQALEASKHLFTEPERFICTT
HHCCCEEECCCCEEEEEEHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEECH
DEIIRQGKMFLHQEWELQDGRTLEQNYIPIVVDHKLYGHLWKYRDITQYKKSEVALRLSE
HHHHHCCHHHHHCCCCCCCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHEEEHH
ERLKLAVDAVEEGLWDWNLVTGEVYRSARWFTMLGYTPMEIGNDIKFRDKLIHPDDIPLM
HHHHHHHHHHHCCCCCCEEEEHHHHHHHCEEEEECCCHHHCCCCCCHHHCCCCCCCCHHH
QQRLISHLKGDTPFYEVEIRLLAKSGEWRWILDRGKLVSRDSQGRAIRMVGTHLDITQRK
HHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEECCCEECCCCCCCEEEEEECCCCHHHHH
QAEQDLQQQYQHTLLLKQITEEIRQSLQWEKILKTTVTEVQRILQVDRALIFQINSDGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
KVVQEAVMPGWSVTLDQDIYDPCLKDGYLNMYRDGRITAIADVYQGGLKPCYVEFLQQFQ
HHHHHHHCCCCEEEECCHHHHHHHHCCCCEEECCCCEEEEHHHHHCCCCHHHHHHHHHHH
VKANLVVPIRVRRNLWGLLIVHQCDRPRQWTELELDLLKHLADQMGIALTQSQLLAQETR
HHCCEEEEEEECCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QAQLLALQNEELNVAKQVAEKANMAKSNFLATMSHEIRTPMNAIIGMSGLLLDTTLKPEQ
HHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEECCCCCCH
FDYVETIRNSSHTLLTIINDILDFSKIESGKLELEEQPFDLRLCVEEALDLLAPQAASKG
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHCCC
IELMYQLEPDTPTLVVGDITRIRQILWNLVSNAVKFTKIGEICITIGAKQKIYKQTDPTR
CEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHCCCCCE
YEFQFAVQDTGIGIERDRLHRLFKPFSQVDASMTRRYGGTGLGLAISKRLSEIMGGKMWV
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
ESQSHQGSIFYFTATLQVNSSAINSAAKVDPELVGKRLLLAVGNANLRKCLTRQLQSLGL
ECCCCCCEEEEEEEEEEECHHHHHHHHCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCC
DVQAVDSNATALHCLWQHTSLALAVLDVDSPQINGLHLSTKIRAIPQHQNLPLVMLSAKG
CEEEECCCCCEEEEEHHCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCEEEEECCC
KQTLEVKQVASEFTAFLHKPLRHYQLHNTLLQIVRGKWLSKSTPQGIIPSYSRLPKPNLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCC
AIDTHLAENLPLKILLVEDVLVNQKIAMNMLHLLGYRTDVANNGLEALEALQRQLYDVVF
CHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MDIQMPEMDGWETTHKIRQEFSPTLQPWIIAMTAHARPEDRQQCLAAGMDDYISKPISLE
EEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHH
DITTALKKFGSQRQPALESPASVSISAPPAPTPQPKIEEVIDQQTLEYLRNLGGSDEADE
HHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DGGGSSIITELIQLYLEDTPAKIQAIQDAATLEDRSQLARIAHALRSPSVSIGAINLGKI
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEHHHH
CETVEDEAKEQSMDQLTALVNQLNNEYQNVVAALKTLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]