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The map label for this gene is phnE [H]

Identifier: 17229719

GI number: 17229719

Start: 2670248

End: 2671072

Strand: Reverse

Name: phnE [H]

Synonym: all2227

Alternate gene names: 17229719

Gene position: 2671072-2670248 (Counterclockwise)

Preceding gene: 17229720

Following gene: 17229717

Centisome position: 41.65

GC content: 40.0

Gene sequence:

>825_bases
GTGCAATCGCAACATCAGCTAATTAGTAACTTGTCACCTAGCGTAGTAGCAATGTTAGAGCAAGAAGCAAAACTTGTGAA
TACCAAAAAAGTTTTGTTTCTTTTAGTGATTGCTGCTATATTGATTTTTGCCTATAACCAAAGCGAGTTAAATTTCCCTG
TACTGCTGCAACGGGGAGACAACATGGCGGAATATATGCGTTCATATTTCCCGCCAGACTTTAGCGATTGGAGATATTAT
TTTTCAGAAACGCTAATCACTATATCGATGGGAATTTGGGGAACTTTAATGGCGGCGATCGCAGCTGTCCCTCTATCTAT
CTTAGCATCTAATAATATGTGTCCAGTATGGGTTGTACAACCAACACGCCGCCTCTTGGATGCTATGCGTGCTATTAATG
AAATCGTTTTTGCATTAATATTTGTAGTTGCTGTAGGGTTAGGGCCGTTTGCTGGCGTATTAGCTTTATTTGTTCATACC
ACAGGCATTTTGGGTAAGCTATTCTCTGAAGCGGTAGAATCAATTGAATCAGGCCCAGTAGAAGGAATTAGAGCCACTGG
TGCAAGTCATATTCAAGAAGTTATTTATGGCGTAATTCCCCAAGTAATGCCTTTGTGGACTTCTTTCACTCTCTATCGAT
TTGAATCAAATGTGCGTTCTGCTTCTGTATTAGGAATAGTCGGGGCTGGTGGTATCGGAGTTTCCTTATATCAGAGTTTT
GGGTCATTTGAATACCAAAAAGTCTGTGCAATTCTCATTATTTTGGTTGTGACTACTGGTGTTATTGATTTACTTTCGGC
GAAGGTTAGAGAGTGGTTTATTTAG

Upstream 100 bases:

>100_bases
TAAAGAAAATCTGAGCGCGCAAGAAAAACAGCAAAAAATAGCAGAACTGAATCAGCAACTCAAAGAGATTCAATAAATTT
ACATTTATAGGTATAAAAAA

Downstream 100 bases:

>100_bases
TGTGATGGTTGACGGTTGATAGTTGACTGTTGACTGTTGACAGGTGACTGTTAAATATTATCTGACTTTTTTTTGCGGGA
GTTAAGATAAGCGTTTAATT

Product: phosphonate ABC tranporter permease protein

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MQSQHQLISNLSPSVVAMLEQEAKLVNTKKVLFLLVIAAILIFAYNQSELNFPVLLQRGDNMAEYMRSYFPPDFSDWRYY
FSETLITISMGIWGTLMAAIAAVPLSILASNNMCPVWVVQPTRRLLDAMRAINEIVFALIFVVAVGLGPFAGVLALFVHT
TGILGKLFSEAVESIESGPVEGIRATGASHIQEVIYGVIPQVMPLWTSFTLYRFESNVRSASVLGIVGAGGIGVSLYQSF
GSFEYQKVCAILIILVVTTGVIDLLSAKVREWFI

Sequences:

>Translated_274_residues
MQSQHQLISNLSPSVVAMLEQEAKLVNTKKVLFLLVIAAILIFAYNQSELNFPVLLQRGDNMAEYMRSYFPPDFSDWRYY
FSETLITISMGIWGTLMAAIAAVPLSILASNNMCPVWVVQPTRRLLDAMRAINEIVFALIFVVAVGLGPFAGVLALFVHT
TGILGKLFSEAVESIESGPVEGIRATGASHIQEVIYGVIPQVMPLWTSFTLYRFESNVRSASVLGIVGAGGIGVSLYQSF
GSFEYQKVCAILIILVVTTGVIDLLSAKVREWFI
>Mature_274_residues
MQSQHQLISNLSPSVVAMLEQEAKLVNTKKVLFLLVIAAILIFAYNQSELNFPVLLQRGDNMAEYMRSYFPPDFSDWRYY
FSETLITISMGIWGTLMAAIAAVPLSILASNNMCPVWVVQPTRRLLDAMRAINEIVFALIFVVAVGLGPFAGVLALFVHT
TGILGKLFSEAVESIESGPVEGIRATGASHIQEVIYGVIPQVMPLWTSFTLYRFESNVRSASVLGIVGAGGIGVSLYQSF
GSFEYQKVCAILIILVVTTGVIDLLSAKVREWFI

Specific function: Part of the binding-protein-dependent transport system for phosphonates; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30107; Mature: 30107

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSQHQLISNLSPSVVAMLEQEAKLVNTKKVLFLLVIAAILIFAYNQSELNFPVLLQRGD
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
NMAEYMRSYFPPDFSDWRYYFSETLITISMGIWGTLMAAIAAVPLSILASNNMCPVWVVQ
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PTRRLLDAMRAINEIVFALIFVVAVGLGPFAGVLALFVHTTGILGKLFSEAVESIESGPV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGIRATGASHIQEVIYGVIPQVMPLWTSFTLYRFESNVRSASVLGIVGAGGIGVSLYQSF
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCHHHHHHHHH
GSFEYQKVCAILIILVVTTGVIDLLSAKVREWFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSQHQLISNLSPSVVAMLEQEAKLVNTKKVLFLLVIAAILIFAYNQSELNFPVLLQRGD
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
NMAEYMRSYFPPDFSDWRYYFSETLITISMGIWGTLMAAIAAVPLSILASNNMCPVWVVQ
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PTRRLLDAMRAINEIVFALIFVVAVGLGPFAGVLALFVHTTGILGKLFSEAVESIESGPV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGIRATGASHIQEVIYGVIPQVMPLWTSFTLYRFESNVRSASVLGIVGAGGIGVSLYQSF
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCHHHHHHHHH
GSFEYQKVCAILIILVVTTGVIDLLSAKVREWFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]