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The map label for this gene is fhuA [H]

Identifier: 17229671

GI number: 17229671

Start: 2619398

End: 2620933

Strand: Direct

Name: fhuA [H]

Synonym: alr2179

Alternate gene names: 17229671

Gene position: 2619398-2620933 (Clockwise)

Preceding gene: 17229670

Following gene: 17229676

Centisome position: 40.84

GC content: 42.9

Gene sequence:

>1536_bases
GTGAGGATATCAATGAAGCTAGATAGGTTGTGCCAAAGCCTGTTGTTAACCAGTGCGATCGCTATTTTAATCCCAAGTCC
CGCCCAAGGTGAGGAAGTTGAAACAGAAATTCGACAAGCCAAGCAAAATATTTCCCAACTGAGCGAAATTGAACTTCCTC
CAACTAACGCTCGAATGTTGGTACAGACACCAACCAATCCCTCTACTCTCCAAGGCGATATTATACCTATAATGGGTGTG
AAAGCTAATCCCACAGAGAAAGGTGTAGAAGTAATTTTAGAGACAGCCGCAGGGGATAAACTGCAAATCACAAATCGCAG
TGAAGATAATAATTTTGTTGCAGATGTTTCTGGTGGGCAGTTGCGTTTACCCAATGGGGATGCTTTCACATTTAAGTCGG
AAAAACCCATCGAGGGAATTACGGAAATTACAGTTACAAACATTGATGTGAATACCGTGCGGGTAACGGTAGTTGGGGAG
AAAGCGTTACCTGCGGTTGAGTTATTTGATGATGATATGGGGTTGATTTTTGCAGTAGCATCTACAGCCACATCTGCACA
AACGCCGGAAACACCAACCGAAGAACAGCCAGCAACAGAGAAACCTGAAGAACAACGCGCAGCCCAGCAGGATGACCCGA
TTGAGTTGGTGGTGACGGGGGAACGGGATAGTTATCGTGTACCGAATGCCAGTACGGCGACGCGGACAGATACACCATTG
CGGGATATTCCCCAATCGATTCAAGTTGTGCCGCAGGAAGTATTGCGCGATCGCAATGCCCAAACTGTGTTTGAGGCAGT
AGAAACCGTTAGTGGTGTTCTTGACGGTTCTAACAACTATGGCGCACCCGGTGGAACCAACATTATTAGAGGATTTATCT
CATTTGACTCAGGAAGTTTACGCAACGGCTTTCGAGATTATGATTACTACTCCGTGTCATCTATCGGGACAATTGAACAA
GTAGAAGTGCTAAAAGGGCCAGCCTCAGTTCTATTCAGCGCGCAGGAACCAGGTGGTGTTATAAATACTGTTACTAAGAA
ACCCCTCAGTACACCCTATTATAATGTCGCATTTCAAGCAGGTAATTATGGATTTTATCAACCAAGTATTGACTTATCAG
GCCCATTAACAACAGATGGAAATGCGTTGTACAGACTTATCACCAGCCATCGAGGTACTGGAAGTTATATAGATTTTGTT
AATTCCAATACAACCACAATTGCACCCTCCATTACCTTAAAATTCGGAGAACGGACAGACCTAAATTTATCTTATGAGTA
CGTTAGATATTTTGCAGATAATCCAATATTTGAAGTTCCGCTACTTACCGATGGTAGCTTACCACCTCGAAATTTTTATT
CTGCCTATCCTGATTTAGTCTTATCTGATATCACAACCAACAGAATTGCTCTAAATCTGAACCACGAATTCAGTGAAAAC
TGGAAACTTCGCAATAATCTGGCAATAGTTCTGAATCAAAGAACTTTGGCTCTTGCGTTGGTTTTATGGTGGAGCATTAA
AATCACAGTTTTATAG

Upstream 100 bases:

>100_bases
GACTGTTAGAACTTTTATGCAATAAGCTGGCTGGATGGGACAGGCTTGCTGACTTTTATGTAAGGTTGCAAATCTGAAAT
TTTCCGGTTGGGTATGATGT

Downstream 100 bases:

>100_bases
AAAGGCTCAAAAACTTAAAACCCAGTCACAGCAATGAATGCAGGCTATCTTTGGGTTTTATTTATTATTCTGTTCCATAA
AATGAACTGAAGAGCCAGAA

Product: ferrichrome-iron receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MRISMKLDRLCQSLLLTSAIAILIPSPAQGEEVETEIRQAKQNISQLSEIELPPTNARMLVQTPTNPSTLQGDIIPIMGV
KANPTEKGVEVILETAAGDKLQITNRSEDNNFVADVSGGQLRLPNGDAFTFKSEKPIEGITEITVTNIDVNTVRVTVVGE
KALPAVELFDDDMGLIFAVASTATSAQTPETPTEEQPATEKPEEQRAAQQDDPIELVVTGERDSYRVPNASTATRTDTPL
RDIPQSIQVVPQEVLRDRNAQTVFEAVETVSGVLDGSNNYGAPGGTNIIRGFISFDSGSLRNGFRDYDYYSVSSIGTIEQ
VEVLKGPASVLFSAQEPGGVINTVTKKPLSTPYYNVAFQAGNYGFYQPSIDLSGPLTTDGNALYRLITSHRGTGSYIDFV
NSNTTTIAPSITLKFGERTDLNLSYEYVRYFADNPIFEVPLLTDGSLPPRNFYSAYPDLVLSDITTNRIALNLNHEFSEN
WKLRNNLAIVLNQRTLALALVLWWSIKITVL

Sequences:

>Translated_511_residues
MRISMKLDRLCQSLLLTSAIAILIPSPAQGEEVETEIRQAKQNISQLSEIELPPTNARMLVQTPTNPSTLQGDIIPIMGV
KANPTEKGVEVILETAAGDKLQITNRSEDNNFVADVSGGQLRLPNGDAFTFKSEKPIEGITEITVTNIDVNTVRVTVVGE
KALPAVELFDDDMGLIFAVASTATSAQTPETPTEEQPATEKPEEQRAAQQDDPIELVVTGERDSYRVPNASTATRTDTPL
RDIPQSIQVVPQEVLRDRNAQTVFEAVETVSGVLDGSNNYGAPGGTNIIRGFISFDSGSLRNGFRDYDYYSVSSIGTIEQ
VEVLKGPASVLFSAQEPGGVINTVTKKPLSTPYYNVAFQAGNYGFYQPSIDLSGPLTTDGNALYRLITSHRGTGSYIDFV
NSNTTTIAPSITLKFGERTDLNLSYEYVRYFADNPIFEVPLLTDGSLPPRNFYSAYPDLVLSDITTNRIALNLNHEFSEN
WKLRNNLAIVLNQRTLALALVLWWSIKITVL
>Mature_511_residues
MRISMKLDRLCQSLLLTSAIAILIPSPAQGEEVETEIRQAKQNISQLSEIELPPTNARMLVQTPTNPSTLQGDIIPIMGV
KANPTEKGVEVILETAAGDKLQITNRSEDNNFVADVSGGQLRLPNGDAFTFKSEKPIEGITEITVTNIDVNTVRVTVVGE
KALPAVELFDDDMGLIFAVASTATSAQTPETPTEEQPATEKPEEQRAAQQDDPIELVVTGERDSYRVPNASTATRTDTPL
RDIPQSIQVVPQEVLRDRNAQTVFEAVETVSGVLDGSNNYGAPGGTNIIRGFISFDSGSLRNGFRDYDYYSVSSIGTIEQ
VEVLKGPASVLFSAQEPGGVINTVTKKPLSTPYYNVAFQAGNYGFYQPSIDLSGPLTTDGNALYRLITSHRGTGSYIDFV
NSNTTTIAPSITLKFGERTDLNLSYEYVRYFADNPIFEVPLLTDGSLPPRNFYSAYPDLVLSDITTNRIALNLNHEFSEN
WKLRNNLAIVLNQRTLALALVLWWSIKITVL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=281, Percent_Identity=28.1138790035587, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787344, Length=306, Percent_Identity=28.1045751633987, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787024, Length=216, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 55930; Mature: 55930

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISMKLDRLCQSLLLTSAIAILIPSPAQGEEVETEIRQAKQNISQLSEIELPPTNARML
CEECCHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VQTPTNPSTLQGDIIPIMGVKANPTEKGVEVILETAAGDKLQITNRSEDNNFVADVSGGQ
EECCCCCCCCCCCEEEEEECCCCCCHHHHHEEEEECCCCEEEEECCCCCCCEEEECCCCE
LRLPNGDAFTFKSEKPIEGITEITVTNIDVNTVRVTVVGEKALPAVELFDDDMGLIFAVA
EECCCCCEEEECCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCEEEEECCCCCEEEEEE
STATSAQTPETPTEEQPATEKPEEQRAAQQDDPIELVVTGERDSYRVPNASTATRTDTPL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCH
RDIPQSIQVVPQEVLRDRNAQTVFEAVETVSGVLDGSNNYGAPGGTNIIRGFISFDSGSL
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCCCCC
RNGFRDYDYYSVSSIGTIEQVEVLKGPASVLFSAQEPGGVINTVTKKPLSTPYYNVAFQA
CCCCCCCCCEECCCCCCHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCEEEEEEE
GNYGFYQPSIDLSGPLTTDGNALYRLITSHRGTGSYIDFVNSNTTTIAPSITLKFGERTD
CCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEEECCCCC
LNLSYEYVRYFADNPIFEVPLLTDGSLPPRNFYSAYPDLVLSDITTNRIALNLNHEFSEN
CCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCEECCCCCCEEEEEECCCCCCC
WKLRNNLAIVLNQRTLALALVLWWSIKITVL
CEEECCEEEEEECHHHHHHHHEEEEEEEEEC
>Mature Secondary Structure
MRISMKLDRLCQSLLLTSAIAILIPSPAQGEEVETEIRQAKQNISQLSEIELPPTNARML
CEECCHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VQTPTNPSTLQGDIIPIMGVKANPTEKGVEVILETAAGDKLQITNRSEDNNFVADVSGGQ
EECCCCCCCCCCCEEEEEECCCCCCHHHHHEEEEECCCCEEEEECCCCCCCEEEECCCCE
LRLPNGDAFTFKSEKPIEGITEITVTNIDVNTVRVTVVGEKALPAVELFDDDMGLIFAVA
EECCCCCEEEECCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCEEEEECCCCCEEEEEE
STATSAQTPETPTEEQPATEKPEEQRAAQQDDPIELVVTGERDSYRVPNASTATRTDTPL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCH
RDIPQSIQVVPQEVLRDRNAQTVFEAVETVSGVLDGSNNYGAPGGTNIIRGFISFDSGSL
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCCCCC
RNGFRDYDYYSVSSIGTIEQVEVLKGPASVLFSAQEPGGVINTVTKKPLSTPYYNVAFQA
CCCCCCCCCEECCCCCCHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCEEEEEEE
GNYGFYQPSIDLSGPLTTDGNALYRLITSHRGTGSYIDFVNSNTTTIAPSITLKFGERTD
CCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEEECCCCC
LNLSYEYVRYFADNPIFEVPLLTDGSLPPRNFYSAYPDLVLSDITTNRIALNLNHEFSEN
CCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCEECCCCCCEEEEEECCCCCCC
WKLRNNLAIVLNQRTLALALVLWWSIKITVL
CEEECCEEEEEECHHHHHHHHEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]