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The map label for this gene is cobK [H]

Identifier: 17229272

GI number: 17229272

Start: 2138754

End: 2139491

Strand: Reverse

Name: cobK [H]

Synonym: all1780

Alternate gene names: 17229272

Gene position: 2139491-2138754 (Counterclockwise)

Preceding gene: 17229273

Following gene: 17229270

Centisome position: 33.36

GC content: 48.78

Gene sequence:

>738_bases
ATGCGCTTGTTAATTCTGGGTGGAACTGGAGATGCAGCCGAACTCAGTGCTAAAGTTGCAACTATTCCAGGTATTGAGGC
GATCGCATCTTTAGCTGGTCGTACCCGTGAACCCTCTCTCCCATCTGGTAACGTCCGTGTGGGGGGTTTTGGTGGTGCGC
CTGGATTAGCTGACTATCTGCGTCAGATGCAGGTTGATTTATTAATTGACGCTACCCACCCTTTTGCTGCACAAATTTCT
GAGAATGCGGCGCTGGCGGCTGATGAGGTGGGGATACCACGTTTGATGTTAATCCGTCCTCCCTGGGTGAAAGTAGCAGG
CGATCGCTGGATAGAAGTTGACACTACAAGCGCCGCCGCCGCTATTTTAAAAAATCAAGCCAAAAGAGTATTTTTAACTG
TTGGCAGACAAGAACTCTCCGCCTTTGCTCATCTACAAGATATTTGGTTTCTCATGCGGATGATTGACCCTCCGGTTGCT
GGTGTTTTAGTTCCGCCTGGGGTGATATTGTGCGATCGCGGCCCCTTTACCCTACCCCAAGAAAAAAACATCCTCATTCA
ACATAATATTGATACTTTAGTTAGTAAAAATAGTGGCGGTGATGCCACCTATGCCAAGATTGTTGCAGCAAGAGAACTAG
GCGTACAAGTTGTCATGGTCAATCGTCCAGCCGTAACAGGCGGCGAACAGGTGACAGACACAGATGCGGCGGTAGCCTGG
CTGCTAGAAAAGTTGTAA

Upstream 100 bases:

>100_bases
GCATTCAAAATGCAAAAGACCTTACATAAAGGTTGCGCCAACAAGCTCCCACTAATTGTCTTTAATTTTGAATTTTGAAT
TGGAGCGAAGCGACTTGACG

Downstream 100 bases:

>100_bases
TCATCAGTTCTGCTACACTCCGTTCATAACAGCCACTTAATTTTTGCTGTTGTACTCGGTTTCCAATGCTTTCAAAACTT
TGAGATATAAGTCTTCCACT

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRLLILGGTGDAAELSAKVATIPGIEAIASLAGRTREPSLPSGNVRVGGFGGAPGLADYLRQMQVDLLIDATHPFAAQIS
ENAALAADEVGIPRLMLIRPPWVKVAGDRWIEVDTTSAAAAILKNQAKRVFLTVGRQELSAFAHLQDIWFLMRMIDPPVA
GVLVPPGVILCDRGPFTLPQEKNILIQHNIDTLVSKNSGGDATYAKIVAARELGVQVVMVNRPAVTGGEQVTDTDAAVAW
LLEKL

Sequences:

>Translated_245_residues
MRLLILGGTGDAAELSAKVATIPGIEAIASLAGRTREPSLPSGNVRVGGFGGAPGLADYLRQMQVDLLIDATHPFAAQIS
ENAALAADEVGIPRLMLIRPPWVKVAGDRWIEVDTTSAAAAILKNQAKRVFLTVGRQELSAFAHLQDIWFLMRMIDPPVA
GVLVPPGVILCDRGPFTLPQEKNILIQHNIDTLVSKNSGGDATYAKIVAARELGVQVVMVNRPAVTGGEQVTDTDAAVAW
LLEKL
>Mature_245_residues
MRLLILGGTGDAAELSAKVATIPGIEAIASLAGRTREPSLPSGNVRVGGFGGAPGLADYLRQMQVDLLIDATHPFAAQIS
ENAALAADEVGIPRLMLIRPPWVKVAGDRWIEVDTTSAAAAILKNQAKRVFLTVGRQELSAFAHLQDIWFLMRMIDPPVA
GVLVPPGVILCDRGPFTLPQEKNILIQHNIDTLVSKNSGGDATYAKIVAARELGVQVVMVNRPAVTGGEQVTDTDAAVAW
LLEKL

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26013; Mature: 26013

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLILGGTGDAAELSAKVATIPGIEAIASLAGRTREPSLPSGNVRVGGFGGAPGLADYL
CEEEEEECCCCHHHHHEEEEECCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHH
RQMQVDLLIDATHPFAAQISENAALAADEVGIPRLMLIRPPWVKVAGDRWIEVDTTSAAA
HHHEEEEEEECCCCHHHHHCCCCEEEECCCCCCEEEEECCCCEEECCCEEEEEECHHHHH
AILKNQAKRVFLTVGRQELSAFAHLQDIWFLMRMIDPPVAGVLVPPGVILCDRGPFTLPQ
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCCCC
EKNILIQHNIDTLVSKNSGGDATYAKIVAARELGVQVVMVNRPAVTGGEQVTDTDAAVAW
CCCEEEEECCHHHEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHH
LLEKL
HHHHC
>Mature Secondary Structure
MRLLILGGTGDAAELSAKVATIPGIEAIASLAGRTREPSLPSGNVRVGGFGGAPGLADYL
CEEEEEECCCCHHHHHEEEEECCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHH
RQMQVDLLIDATHPFAAQISENAALAADEVGIPRLMLIRPPWVKVAGDRWIEVDTTSAAA
HHHEEEEEEECCCCHHHHHCCCCEEEECCCCCCEEEEECCCCEEECCCEEEEEECHHHHH
AILKNQAKRVFLTVGRQELSAFAHLQDIWFLMRMIDPPVAGVLVPPGVILCDRGPFTLPQ
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCCCC
EKNILIQHNIDTLVSKNSGGDATYAKIVAARELGVQVVMVNRPAVTGGEQVTDTDAAVAW
CCCEEEEECCHHHEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHH
LLEKL
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]