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The map label for this gene is coaE [H]

Identifier: 17229246

GI number: 17229246

Start: 2108626

End: 2109216

Strand: Reverse

Name: coaE [H]

Synonym: all1754

Alternate gene names: 17229246

Gene position: 2109216-2108626 (Counterclockwise)

Preceding gene: 17229247

Following gene: 17229243

Centisome position: 32.89

GC content: 40.27

Gene sequence:

>591_bases
ATGACCCAACGCATTATCGGCTTAACTGGAGGTATAGCGACAGGTAAAACCACTGTCGCTAATTATTTAGCTAGCGCTCA
TAATTTGCCAATCTTCGACGCAGATATTTACGCTAGGGATGCAGTATCTTTAGGTTCGCCGATTCTGGATGCGATCGCTA
GGCGTTATGGTAAAGAAATATTACTACCAGATGGCAGTCTCAACCGCCCAAAGTTGGGTGAGATGATCTTTCAGAATCAA
GATCAACGCCATTGGGTAGAAAGTTTAATACATCCTTATGTGCGCGATCGCTTTCTCAAAGCAATTGCTGAATCCACTTC
CCCAATACTGGTATTAGTCATACCTTTGTTGATTGAAGTGCAGATGACGAATTTAGTCACAGAAATTTGGGTAGTAATTT
GTTCGGAATCACAGCAGTTGCAAAGATTAATGGAGCGCAATCACTTAACTTTAGAACAAGCACAAGCCCGAATTAATAGT
CAATTATCTCTAAAAGAAAAAGCAGCGATCGCAGATGTAGTTTTAGATAACTCTTCATCTTTAGACGCACTGCTCAAACA
AGTAGATATCGCTCTTAATTTTGAACTTTGA

Upstream 100 bases:

>100_bases
CAAAATATTGTGGTGATGTTTAAGATTAATTCCTAACACCCTACGGAAAGCAAGCTACGTAATTCCTAATTTGTGATTAC
GTTAAGCGCAAGTAAAAGAG

Downstream 100 bases:

>100_bases
ATTTTGTAGCTTTAGCTTCCAGTAGGGTATTTTGAATTGACTACATTTCTCCCCCAACTACTACATCTCGAATCCGTAAA
CTAGGGCCGCCACAACCGAC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTQRIIGLTGGIATGKTTVANYLASAHNLPIFDADIYARDAVSLGSPILDAIARRYGKEILLPDGSLNRPKLGEMIFQNQ
DQRHWVESLIHPYVRDRFLKAIAESTSPILVLVIPLLIEVQMTNLVTEIWVVICSESQQLQRLMERNHLTLEQAQARINS
QLSLKEKAAIADVVLDNSSSLDALLKQVDIALNFEL

Sequences:

>Translated_196_residues
MTQRIIGLTGGIATGKTTVANYLASAHNLPIFDADIYARDAVSLGSPILDAIARRYGKEILLPDGSLNRPKLGEMIFQNQ
DQRHWVESLIHPYVRDRFLKAIAESTSPILVLVIPLLIEVQMTNLVTEIWVVICSESQQLQRLMERNHLTLEQAQARINS
QLSLKEKAAIADVVLDNSSSLDALLKQVDIALNFEL
>Mature_195_residues
TQRIIGLTGGIATGKTTVANYLASAHNLPIFDADIYARDAVSLGSPILDAIARRYGKEILLPDGSLNRPKLGEMIFQNQD
QRHWVESLIHPYVRDRFLKAIAESTSPILVLVIPLLIEVQMTNLVTEIWVVICSESQQLQRLMERNHLTLEQAQARINSQ
LSLKEKAAIADVVLDNSSSLDALLKQVDIALNFEL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=37.7551020408163, Blast_Score=121, Evalue=3e-28,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=37.7551020408163, Blast_Score=121, Evalue=3e-28,
Organism=Homo sapiens, GI110227607, Length=175, Percent_Identity=30.2857142857143, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI205277394, Length=177, Percent_Identity=29.9435028248588, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI110227605, Length=177, Percent_Identity=29.9435028248588, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI110227603, Length=177, Percent_Identity=29.9435028248588, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI110227601, Length=177, Percent_Identity=29.9435028248588, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI1786292, Length=184, Percent_Identity=37.5, Blast_Score=129, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=32.2751322751323, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=29.7872340425532, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320402, Length=192, Percent_Identity=38.0208333333333, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=33.5164835164835, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24658602, Length=194, Percent_Identity=29.8969072164948, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21827; Mature: 21695

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRIIGLTGGIATGKTTVANYLASAHNLPIFDADIYARDAVSLGSPILDAIARRYGKEI
CCCEEEEECCCCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHCCCHHHHHHHHHHCCEE
LLPDGSLNRPKLGEMIFQNQDQRHWVESLIHPYVRDRFLKAIAESTSPILVLVIPLLIEV
ECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QMTNLVTEIWVVICSESQQLQRLMERNHLTLEQAQARINSQLSLKEKAAIADVVLDNSSS
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
LDALLKQVDIALNFEL
HHHHHHHHHHHEECCC
>Mature Secondary Structure 
TQRIIGLTGGIATGKTTVANYLASAHNLPIFDADIYARDAVSLGSPILDAIARRYGKEI
CCEEEEECCCCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHCCCHHHHHHHHHHCCEE
LLPDGSLNRPKLGEMIFQNQDQRHWVESLIHPYVRDRFLKAIAESTSPILVLVIPLLIEV
ECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QMTNLVTEIWVVICSESQQLQRLMERNHLTLEQAQARINSQLSLKEKAAIADVVLDNSSS
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
LDALLKQVDIALNFEL
HHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA