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The map label for this gene is prpC [H]

Identifier: 17229223

GI number: 17229223

Start: 2082221

End: 2084497

Strand: Reverse

Name: prpC [H]

Synonym: all1731

Alternate gene names: 17229223

Gene position: 2084497-2082221 (Counterclockwise)

Preceding gene: 17229224

Following gene: 17229222

Centisome position: 32.5

GC content: 45.85

Gene sequence:

>2277_bases
ATGGAAAATGATGCGGCAACGCTCTACTGTCCAAACGAACTTTGTCAGGCTGCGAACCCCCTGACACACAAGTTTTGCCA
GCGATGCTCCACACCCTTACCCAAGCGTTATTTGTGGGTGGTGGGAGATAGTCTGAGTATTGGCAGTACCGGAGAAATAT
TAGCCGATCGCTATTTAATTATCAATCAGTCTGTTGTTTTAGATACTAAACCCGGTTTACTACCCCAAGCGCCCGATTTA
GAAAATACCCATCCCATCAGACCTTATCTGCGGCTCATCCCCTATCGGTTAAATATCCCCCAAGTGTATGGGATGCTGCC
GATAACCGATGGCTACGTCCACAGTCAAGTTCTATTGTTGGAAAAATCTCCTCTGTTCGCAGACAATTTAGCTCAACAGG
TGCATTTGTGTAGCGAATTTACCGATGCTTGGCGCTACGCTACATCAATGCGCCAACTACATTGGCTGTGGCAAATTGCC
AATCTTTGGCAACCTTTCAAGAGTGAAGGCGTTGTATCTAGCCTACTCAACCCATACCTGTTGCGGGTGGAAGGGCCATT
AGTGCGGTTGTTGGAGCTGCATTCTGACTCGACAACGGCGCTAGAATTGCCACAATTGGGCGAATTTTGGCAACAACTAC
ACCAGGAAGCCAAACCAGCCATAGCAGAATTTGTTCAGCAAATTAGTCATTTGCTAATTCAAGGCGAAATCAAATCCTCA
GAGGTACTAGTTGCCGTTTTAGATAGAGGATTGGCAGAACTAAGCAAATCACAAACACCTACCATTCAAATTGCCACTAA
AACCGACACCGGCCCCAGCCGTCAACGGAACGAAGATGCTTGTTATCCTCCCAGTGGCACACTATTGAGCAAACCACCCC
AACCCACTGCCTTGGCTATTGTTTGTGATGGCATTGGTGGACATGAAGGCGGCAATGTTGCTTCTAATTTAGCAATTGAA
ACTATCCAGAAACAGGTACAACAGCTGACCAACGTACCACCAGACCACATTGAACCATCACTGTTGATAGCTGATTTAGA
ACGGGCAGCAGCCGTTGCCAACGACAAAATTAGTCAGCGCAATGACAGCGAAAATCGCCAAGGGCGAAAACGCATGGGTA
CAACCTTGGTGATGGCTTTACCTATTGCCCACGAAATGTATATTACCCACGTCGGCGACAGTCGCGCCTATTGGATCACC
CGTCACGGTTGTTATCAAGTTACCCTTGATGATGATGTGGCATCACGGGAAGTAAGATTAGGCTACGCTGTCTACCGTGA
AGCGGTACAACAAGGTGGTTCAGGTTCGCTGGTGCAAGCTTTAGGCATGAGTCCCAGCAGTTCACTACATCCCACAGCGC
AACGATTTATCCTCGATGAAGATGGGGTGTTTCTGTTGACTTCCGACGGGTTAAGTGATTTTGACCGTGTAGAAGACTAT
TGGGAAACGGAGATTTTACCAATTCTCACGGGTGAAGAAAATAATATAGTTAACGTGGTTGAGCGATTGGTAGACATCGC
TAACACGAAGAATGGACATGATAATGTGACGATCGCCCTAGTCAATTGTCGAATTAAATACACCGAACCACAAATCACTC
TGAAGGCCGTTGTTCCCGACAGCACTCATATCAAAACTGTAAATCTGACATCAAGAGGGCTACAGCCAACCTTACTAGAG
GCTAAACCAGAACAAAAAACTAAAGTAGTTCCCAGCAACTTACCCAATAGAATCAGCAAACTACCCCTAAATCTCATCGT
GCCGTTAATCTTGGTGGCGACAGCTGGTGTCTTGGGATATTGGGTCATGTTACTGCGATCGCCATACGCCAATCCCACAG
TCACCCCAACTGGGACTTTACCATCAGCCACCCAGAGTCCCAAAGTACAGCAGCGATCGGTGAATAATCTCGCACCTGGA
TGGATAATTAAAACTAACAGTGAAATCACCTTCAATCAACAAAAGTTACCCCCAGAAAGTTTTTTAGAAGTGATTGATAA
AAAATTCAATCCTCAACCTGCTCCAGGGATTTATGAAGTATATTTACGTCTTTGTAACCCCCAGCCAGCTAGCACTAATA
ATTTAGCCACAGAACCTCTGCCACCTTCAGATCAACCAATCAAAACGGAATTAGCTCAACTGAAACGATTTGCTGTGACA
GTTTTACAACCCAATCAAGACAGCCCTTGTGATAGTATCTCTCTGCCACGAGACATCTCACCTCCAGCAGCAAATACTCC
TAACAATCCAGGTGCAGATGAATCAAATAATCGATAA

Upstream 100 bases:

>100_bases
CACGATGGATAACTCGAATTCAAGAAATATGAGCGGTCTTCATTCTTGCCGCTACCAGTGCTGTTGAAACAATTGCCAAT
CGCTGATCGGTGCGAACACT

Downstream 100 bases:

>100_bases
ACTGATAAAAACCTGAAATAATACAGATAATAACAAAACGCAATTTACAAGCCAAAAGTTTTTCTTAAGAAAAATTACAG
TTGGCAATTATCGTAAATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 758; Mature: 758

Protein sequence:

>758_residues
MENDAATLYCPNELCQAANPLTHKFCQRCSTPLPKRYLWVVGDSLSIGSTGEILADRYLIINQSVVLDTKPGLLPQAPDL
ENTHPIRPYLRLIPYRLNIPQVYGMLPITDGYVHSQVLLLEKSPLFADNLAQQVHLCSEFTDAWRYATSMRQLHWLWQIA
NLWQPFKSEGVVSSLLNPYLLRVEGPLVRLLELHSDSTTALELPQLGEFWQQLHQEAKPAIAEFVQQISHLLIQGEIKSS
EVLVAVLDRGLAELSKSQTPTIQIATKTDTGPSRQRNEDACYPPSGTLLSKPPQPTALAIVCDGIGGHEGGNVASNLAIE
TIQKQVQQLTNVPPDHIEPSLLIADLERAAAVANDKISQRNDSENRQGRKRMGTTLVMALPIAHEMYITHVGDSRAYWIT
RHGCYQVTLDDDVASREVRLGYAVYREAVQQGGSGSLVQALGMSPSSSLHPTAQRFILDEDGVFLLTSDGLSDFDRVEDY
WETEILPILTGEENNIVNVVERLVDIANTKNGHDNVTIALVNCRIKYTEPQITLKAVVPDSTHIKTVNLTSRGLQPTLLE
AKPEQKTKVVPSNLPNRISKLPLNLIVPLILVATAGVLGYWVMLLRSPYANPTVTPTGTLPSATQSPKVQQRSVNNLAPG
WIIKTNSEITFNQQKLPPESFLEVIDKKFNPQPAPGIYEVYLRLCNPQPASTNNLATEPLPPSDQPIKTELAQLKRFAVT
VLQPNQDSPCDSISLPRDISPPAANTPNNPGADESNNR

Sequences:

>Translated_758_residues
MENDAATLYCPNELCQAANPLTHKFCQRCSTPLPKRYLWVVGDSLSIGSTGEILADRYLIINQSVVLDTKPGLLPQAPDL
ENTHPIRPYLRLIPYRLNIPQVYGMLPITDGYVHSQVLLLEKSPLFADNLAQQVHLCSEFTDAWRYATSMRQLHWLWQIA
NLWQPFKSEGVVSSLLNPYLLRVEGPLVRLLELHSDSTTALELPQLGEFWQQLHQEAKPAIAEFVQQISHLLIQGEIKSS
EVLVAVLDRGLAELSKSQTPTIQIATKTDTGPSRQRNEDACYPPSGTLLSKPPQPTALAIVCDGIGGHEGGNVASNLAIE
TIQKQVQQLTNVPPDHIEPSLLIADLERAAAVANDKISQRNDSENRQGRKRMGTTLVMALPIAHEMYITHVGDSRAYWIT
RHGCYQVTLDDDVASREVRLGYAVYREAVQQGGSGSLVQALGMSPSSSLHPTAQRFILDEDGVFLLTSDGLSDFDRVEDY
WETEILPILTGEENNIVNVVERLVDIANTKNGHDNVTIALVNCRIKYTEPQITLKAVVPDSTHIKTVNLTSRGLQPTLLE
AKPEQKTKVVPSNLPNRISKLPLNLIVPLILVATAGVLGYWVMLLRSPYANPTVTPTGTLPSATQSPKVQQRSVNNLAPG
WIIKTNSEITFNQQKLPPESFLEVIDKKFNPQPAPGIYEVYLRLCNPQPASTNNLATEPLPPSDQPIKTELAQLKRFAVT
VLQPNQDSPCDSISLPRDISPPAANTPNNPGADESNNR
>Mature_758_residues
MENDAATLYCPNELCQAANPLTHKFCQRCSTPLPKRYLWVVGDSLSIGSTGEILADRYLIINQSVVLDTKPGLLPQAPDL
ENTHPIRPYLRLIPYRLNIPQVYGMLPITDGYVHSQVLLLEKSPLFADNLAQQVHLCSEFTDAWRYATSMRQLHWLWQIA
NLWQPFKSEGVVSSLLNPYLLRVEGPLVRLLELHSDSTTALELPQLGEFWQQLHQEAKPAIAEFVQQISHLLIQGEIKSS
EVLVAVLDRGLAELSKSQTPTIQIATKTDTGPSRQRNEDACYPPSGTLLSKPPQPTALAIVCDGIGGHEGGNVASNLAIE
TIQKQVQQLTNVPPDHIEPSLLIADLERAAAVANDKISQRNDSENRQGRKRMGTTLVMALPIAHEMYITHVGDSRAYWIT
RHGCYQVTLDDDVASREVRLGYAVYREAVQQGGSGSLVQALGMSPSSSLHPTAQRFILDEDGVFLLTSDGLSDFDRVEDY
WETEILPILTGEENNIVNVVERLVDIANTKNGHDNVTIALVNCRIKYTEPQITLKAVVPDSTHIKTVNLTSRGLQPTLLE
AKPEQKTKVVPSNLPNRISKLPLNLIVPLILVATAGVLGYWVMLLRSPYANPTVTPTGTLPSATQSPKVQQRSVNNLAPG
WIIKTNSEITFNQQKLPPESFLEVIDKKFNPQPAPGIYEVYLRLCNPQPASTNNLATEPLPPSDQPIKTELAQLKRFAVT
VLQPNQDSPCDSISLPRDISPPAANTPNNPGADESNNR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 83714; Mature: 83714

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENDAATLYCPNELCQAANPLTHKFCQRCSTPLPKRYLWVVGDSLSIGSTGEILADRYLI
CCCCCEEEECCHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHCCEEE
INQSVVLDTKPGLLPQAPDLENTHPIRPYLRLIPYRLNIPQVYGMLPITDGYVHSQVLLL
EECEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCEEECCCCCCCCEEEEE
EKSPLFADNLAQQVHLCSEFTDAWRYATSMRQLHWLWQIANLWQPFKSEGVVSSLLNPYL
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEE
LRVEGPLVRLLELHSDSTTALELPQLGEFWQQLHQEAKPAIAEFVQQISHLLIQGEIKSS
EEECCHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEECCCCCC
EVLVAVLDRGLAELSKSQTPTIQIATKTDTGPSRQRNEDACYPPSGTLLSKPPQPTALAI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VCDGIGGHEGGNVASNLAIETIQKQVQQLTNVPPDHIEPSLLIADLERAAAVANDKISQR
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHCC
NDSENRQGRKRMGTTLVMALPIAHEMYITHVGDSRAYWITRHGCYQVTLDDDVASREVRL
CCCHHHHHHHHHCCEEEEEEHHHEEEEEEEECCCCEEEEEECCEEEEEECCCCCCHHHHH
GYAVYREAVQQGGSGSLVQALGMSPSSSLHPTAQRFILDEDGVFLLTSDGLSDFDRVEDY
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHEEECCCCEEEEECCCCCHHHHHHHH
WETEILPILTGEENNIVNVVERLVDIANTKNGHDNVTIALVNCRIKYTEPQITLKAVVPD
HCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCEEEEEECCC
STHIKTVNLTSRGLQPTLLEAKPEQKTKVVPSNLPNRISKLPLNLIVPLILVATAGVLGY
CCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
WVMLLRSPYANPTVTPTGTLPSATQSPKVQQRSVNNLAPGWIIKTNSEITFNQQKLPPES
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCEEEECHHCCCHHH
FLEVIDKKFNPQPAPGIYEVYLRLCNPQPASTNNLATEPLPPSDQPIKTELAQLKRFAVT
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEE
VLQPNQDSPCDSISLPRDISPPAANTPNNPGADESNNR
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MENDAATLYCPNELCQAANPLTHKFCQRCSTPLPKRYLWVVGDSLSIGSTGEILADRYLI
CCCCCEEEECCHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHCCEEE
INQSVVLDTKPGLLPQAPDLENTHPIRPYLRLIPYRLNIPQVYGMLPITDGYVHSQVLLL
EECEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCEEECCCCCCCCEEEEE
EKSPLFADNLAQQVHLCSEFTDAWRYATSMRQLHWLWQIANLWQPFKSEGVVSSLLNPYL
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEE
LRVEGPLVRLLELHSDSTTALELPQLGEFWQQLHQEAKPAIAEFVQQISHLLIQGEIKSS
EEECCHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEECCCCCC
EVLVAVLDRGLAELSKSQTPTIQIATKTDTGPSRQRNEDACYPPSGTLLSKPPQPTALAI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VCDGIGGHEGGNVASNLAIETIQKQVQQLTNVPPDHIEPSLLIADLERAAAVANDKISQR
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHCC
NDSENRQGRKRMGTTLVMALPIAHEMYITHVGDSRAYWITRHGCYQVTLDDDVASREVRL
CCCHHHHHHHHHCCEEEEEEHHHEEEEEEEECCCCEEEEEECCEEEEEECCCCCCHHHHH
GYAVYREAVQQGGSGSLVQALGMSPSSSLHPTAQRFILDEDGVFLLTSDGLSDFDRVEDY
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHEEECCCCEEEEECCCCCHHHHHHHH
WETEILPILTGEENNIVNVVERLVDIANTKNGHDNVTIALVNCRIKYTEPQITLKAVVPD
HCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCEEEEEECCC
STHIKTVNLTSRGLQPTLLEAKPEQKTKVVPSNLPNRISKLPLNLIVPLILVATAGVLGY
CCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
WVMLLRSPYANPTVTPTGTLPSATQSPKVQQRSVNNLAPGWIIKTNSEITFNQQKLPPES
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCEEEECHHCCCHHH
FLEVIDKKFNPQPAPGIYEVYLRLCNPQPASTNNLATEPLPPSDQPIKTELAQLKRFAVT
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEE
VLQPNQDSPCDSISLPRDISPPAANTPNNPGADESNNR
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]