Click here to switch to the map view.

The map label for this gene is iolE [H]

Identifier: 17229072

GI number: 17229072

Start: 1848817

End: 1849932

Strand: Direct

Name: iolE [H]

Synonym: alr1580

Alternate gene names: 17229072

Gene position: 1848817-1849932 (Clockwise)

Preceding gene: 17229071

Following gene: 17229073

Centisome position: 28.83

GC content: 38.71

Gene sequence:

>1116_bases
ATGTTGGCAAAAAATGAGTGCAAGATTAATAGATCATCAATTTTGTCCAAAATCAAAGAGATTCGTCGTTTATTTGCCCT
ATCATTTGTCTTTATCTTGGTGGGGATAAATAGCTTTATACTTCCCGCTACTGCTGCTCCAAGTGGAAACAATTCGGTTC
TAGTATCTCTAGTTACTCCTTCATCTAAACCTGCACTCTTAAACCCAACATTCGACCCCACAAAAGTCAATTTGGGCATC
ACACCGACTGGTTGGAGTAATAGTGATGATCTGACTATTGATCTTGACCCCCCTATCCCTTTTGAGCAGATTTTAAGTGA
AATGGCACTATCTGGCTTCAAAGGTTCGCAAATGTCACCTAAGTTTCCCTCAAAAATCAAGGATTTAAAAAAAGAGTTAA
AACTTCGTGATTTGAAAATTTCTGAACCTTGGGTAGGAACTTTATTCACAGAGGGAAAGGACGATGAAACCCTTAAAGAA
TTCAACAAGCAAGTAGCTTTCATGAAGGAAATGAAGGGCAAAAATATTGTGGTTGCTGAATTGGGTGGTGCTGTTCATCA
AAAGAAATGTGTAGACCCTTTAGTTAACAGACCTCGTTTTACTGACGAGCAATGGGTGGATTTAGTTAAGGGGCTAAATA
AACTGGGTTCCATCGCCAACGAAAACGGTATGCAGTTGGTTTATCATCCTCATATTGGTACAGGAGTAGAAAACTTCGCG
GATATTGACCGATTGATGAAAGGTACTGATTCTGAAAATGTTAAGCTGCTGCTTGATACTGGTCATTTGTACTATGCAGG
AGTTGATCCTCTAGCAGTCACTAAAAAGTATGCTAATCGGATCAAACACGTTCATCTGAAAAATATTCGTCAGCCAATTT
TAGATGCGTCGAAAAAAACTGGTCGTAGCTTTTTAGACTCCATCCGAGCAGGAATATTTACTGTTCCGGGAGATAAAGAT
GGTGCAATTGATTTTCAGCCAATTTTACAAGAGCTTGCTAAAGCTAAATATGAAGGATGGCTGATGGTAGAGGCAGAACA
AGATCCAAACAAAGCTAATCCTTTAACTTATGCTTTAATAGCTCGTAATTATTTACGCCAAGTGACTGACTTATAA

Upstream 100 bases:

>100_bases
TTCAAAAATCAAGTATGAGTCCTATATATATTTAACTCATTGCTGATTATTTGAGAGTTCTAATTTACATACCTGAGCAA
AGAATAGGAATCAATAAGTC

Downstream 100 bases:

>100_bases
CCTATTTCCATGAATAGCATACCTTTAAAATTGCTATTCACTTTTGTTGTAATCTATTTCAACATTGTCATACTATCTAC
ATCTGGGAAGCTGTTCCACA

Product: hypothetical protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MLAKNECKINRSSILSKIKEIRRLFALSFVFILVGINSFILPATAAPSGNNSVLVSLVTPSSKPALLNPTFDPTKVNLGI
TPTGWSNSDDLTIDLDPPIPFEQILSEMALSGFKGSQMSPKFPSKIKDLKKELKLRDLKISEPWVGTLFTEGKDDETLKE
FNKQVAFMKEMKGKNIVVAELGGAVHQKKCVDPLVNRPRFTDEQWVDLVKGLNKLGSIANENGMQLVYHPHIGTGVENFA
DIDRLMKGTDSENVKLLLDTGHLYYAGVDPLAVTKKYANRIKHVHLKNIRQPILDASKKTGRSFLDSIRAGIFTVPGDKD
GAIDFQPILQELAKAKYEGWLMVEAEQDPNKANPLTYALIARNYLRQVTDL

Sequences:

>Translated_371_residues
MLAKNECKINRSSILSKIKEIRRLFALSFVFILVGINSFILPATAAPSGNNSVLVSLVTPSSKPALLNPTFDPTKVNLGI
TPTGWSNSDDLTIDLDPPIPFEQILSEMALSGFKGSQMSPKFPSKIKDLKKELKLRDLKISEPWVGTLFTEGKDDETLKE
FNKQVAFMKEMKGKNIVVAELGGAVHQKKCVDPLVNRPRFTDEQWVDLVKGLNKLGSIANENGMQLVYHPHIGTGVENFA
DIDRLMKGTDSENVKLLLDTGHLYYAGVDPLAVTKKYANRIKHVHLKNIRQPILDASKKTGRSFLDSIRAGIFTVPGDKD
GAIDFQPILQELAKAKYEGWLMVEAEQDPNKANPLTYALIARNYLRQVTDL
>Mature_371_residues
MLAKNECKINRSSILSKIKEIRRLFALSFVFILVGINSFILPATAAPSGNNSVLVSLVTPSSKPALLNPTFDPTKVNLGI
TPTGWSNSDDLTIDLDPPIPFEQILSEMALSGFKGSQMSPKFPSKIKDLKKELKLRDLKISEPWVGTLFTEGKDDETLKE
FNKQVAFMKEMKGKNIVVAELGGAVHQKKCVDPLVNRPRFTDEQWVDLVKGLNKLGSIANENGMQLVYHPHIGTGVENFA
DIDRLMKGTDSENVKLLLDTGHLYYAGVDPLAVTKKYANRIKHVHLKNIRQPILDASKKTGRSFLDSIRAGIFTVPGDKD
GAIDFQPILQELAKAKYEGWLMVEAEQDPNKANPLTYALIARNYLRQVTDL

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 41214; Mature: 41214

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKNECKINRSSILSKIKEIRRLFALSFVFILVGINSFILPATAAPSGNNSVLVSLVTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECC
SSKPALLNPTFDPTKVNLGITPTGWSNSDDLTIDLDPPIPFEQILSEMALSGFKGSQMSP
CCCCCEECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
KFPSKIKDLKKELKLRDLKISEPWVGTLFTEGKDDETLKEFNKQVAFMKEMKGKNIVVAE
CCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
LGGAVHQKKCVDPLVNRPRFTDEQWVDLVKGLNKLGSIANENGMQLVYHPHIGTGVENFA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
DIDRLMKGTDSENVKLLLDTGHLYYAGVDPLAVTKKYANRIKHVHLKNIRQPILDASKKT
HHHHHHCCCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRSFLDSIRAGIFTVPGDKDGAIDFQPILQELAKAKYEGWLMVEAEQDPNKANPLTYALI
HHHHHHHHHHCEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHH
ARNYLRQVTDL
HHHHHHHHHCC
>Mature Secondary Structure
MLAKNECKINRSSILSKIKEIRRLFALSFVFILVGINSFILPATAAPSGNNSVLVSLVTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECC
SSKPALLNPTFDPTKVNLGITPTGWSNSDDLTIDLDPPIPFEQILSEMALSGFKGSQMSP
CCCCCEECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
KFPSKIKDLKKELKLRDLKISEPWVGTLFTEGKDDETLKEFNKQVAFMKEMKGKNIVVAE
CCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
LGGAVHQKKCVDPLVNRPRFTDEQWVDLVKGLNKLGSIANENGMQLVYHPHIGTGVENFA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
DIDRLMKGTDSENVKLLLDTGHLYYAGVDPLAVTKKYANRIKHVHLKNIRQPILDASKKT
HHHHHHCCCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRSFLDSIRAGIFTVPGDKDGAIDFQPILQELAKAKYEGWLMVEAEQDPNKANPLTYALI
HHHHHHHHHHCEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHH
ARNYLRQVTDL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]