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The map label for this gene is 17228118

Identifier: 17228118

GI number: 17228118

Start: 720570

End: 722213

Strand: Direct

Name: 17228118

Synonym: alr0622

Alternate gene names: NA

Gene position: 720570-722213 (Clockwise)

Preceding gene: 17228114

Following gene: 17228123

Centisome position: 11.23

GC content: 37.41

Gene sequence:

>1644_bases
ATGGACTGGATTACGCTACTGCGATCGCTACAGTCTGATTTTATTAAAAGGTTATCATCTGGTTGTCTGCTGCATTGCGA
AATCGAAGGTCAATATAGTGAGTTAACGGTTATCTCTGGCGAAAGATTAAAAACCCTACGAGACTTTTGCTGGCTGATGG
CTGAAAAATATAAGCGGGTTTCGCCAGTTCGTGATGTTTTTATCAGCTACCTCAAGGGTAAATTGGGGGAGGAAGTTGTT
AAAGAACGTTTAGCTGATTTGATTACCGAAGTAGATTATGAAAAGCGACTTGGTGGCGACGGTAAGATAGATTTTACTTT
AACTGCTAACCCTGCAATTGGCATTGAAGTTAAATCTCGTCATGGCAACATTGATAGAGTGAGATGGTCAGTTAGTGCCG
AAGAAGTGGAAAAAAATGCAGTTGTAGTTTGCATTTTTATTAAAGAAGATGTTAACGAAGCACAATCATCATATCATCTG
TTATTAGCAGGCTTTTTGCCTACTCAAATGATTAAATTAAAGACAGGTAATATCTCATTTGGAATAGAGCAGTTACTTTA
CGGTGGCGGCTTATGGGGTTATTTGGAACAGTTGCAAGCTTCCGCAAATTACCATCAGTTCCAGCAATCTCCGCCAATTT
ATCAATACAAACCCCAGCCAGAATTATTATCTAAGATCAATCAAACTCAATCAATCAAACCAGCTTTATTTACTGGTATC
AAAAATATTCTACCCTATAGACAACAAGAAGCGATAAATATAGATTATATCAAAATTGGTGATGAGTGCTTTGCTCAGGG
AGAATATACCGCATCTATTAAAAATTATAGCCAAGCTTTACAAGCAAGTAGTGATAATTGTGAATTATACTATAAACGAG
GTTTAAGCTATTATCAATTGGGTGATTATGAGGCGGCGATCGCCGATTATTCTCAAGCCATAAATATCAACCTTCACGAT
GCTAAATCCTATCATAAACGTGGGTTAGCTTTATCACAACTAGCAGCTTATGAAGCGGCAATCGATGATTATAATCAAGC
AATTAGAATTAATCCCCATGCTGCTTCTATTTATAAAAACCGAGCAGAAGCACGCTCTCATCTAGGAGATAATCAAGGAG
CGATTGAAGATTATACCCAAGCGATCAAGATTAATCCCCAATATGCAGATACATATAAAAATAGAGGCATATCTCGTTAT
TTATTAGCAACACAACCAGGATTTACCCAAGCAATTAAGATTAATCCCAATGATGCTAATGCTTACAAAAATCGTGGTAA
TGCGCGTGCTGATATTGGTGATTATCTAGGAGCGATTGAAGATTATAATCAGGCAATCCAAATTAATCCCAAGGCGGCTG
ATGCTTATTATAACCGTGGTAACGCCCGTTATGATTTAGGGGATGAAGAAGGAGCGATCGCTGATTACACCCAAGCAATC
CAAATTAATCCCAGCTATGCTGATGCTTATTATAACCGTGGTAATGTGCGTGCAGGCATCAAAGATAAACAAGGAGCGAT
CGCTGACTTTCAAAAAGCGGCAGATATATATCGTAAAGAAGGTAAATTAGCAGAACTCAAAGATACAACAGAAAGAGTTG
TAGAATTGGAAATAGAAGAATCAATTGATATTTTAAATTTTTAA

Upstream 100 bases:

>100_bases
ATACCCTCAATTTGCCAGAAATTTATGATGGTGTCTTTGAGGTAGCTCAAAGAAGGAGATAAAATAAGGTAAAATCATCA
AAAAACTCGCAGAACTATAA

Downstream 100 bases:

>100_bases
ATTCAAAATATCAGCCAGTAAAATGAGTGATAAGCTAATGCGCGTCTAAATTGCATAACTACTAACAAGCTGTTAACTGT
TAACAGTCAACGGTTAACAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MDWITLLRSLQSDFIKRLSSGCLLHCEIEGQYSELTVISGERLKTLRDFCWLMAEKYKRVSPVRDVFISYLKGKLGEEVV
KERLADLITEVDYEKRLGGDGKIDFTLTANPAIGIEVKSRHGNIDRVRWSVSAEEVEKNAVVVCIFIKEDVNEAQSSYHL
LLAGFLPTQMIKLKTGNISFGIEQLLYGGGLWGYLEQLQASANYHQFQQSPPIYQYKPQPELLSKINQTQSIKPALFTGI
KNILPYRQQEAINIDYIKIGDECFAQGEYTASIKNYSQALQASSDNCELYYKRGLSYYQLGDYEAAIADYSQAININLHD
AKSYHKRGLALSQLAAYEAAIDDYNQAIRINPHAASIYKNRAEARSHLGDNQGAIEDYTQAIKINPQYADTYKNRGISRY
LLATQPGFTQAIKINPNDANAYKNRGNARADIGDYLGAIEDYNQAIQINPKAADAYYNRGNARYDLGDEEGAIADYTQAI
QINPSYADAYYNRGNVRAGIKDKQGAIADFQKAADIYRKEGKLAELKDTTERVVELEIEESIDILNF

Sequences:

>Translated_547_residues
MDWITLLRSLQSDFIKRLSSGCLLHCEIEGQYSELTVISGERLKTLRDFCWLMAEKYKRVSPVRDVFISYLKGKLGEEVV
KERLADLITEVDYEKRLGGDGKIDFTLTANPAIGIEVKSRHGNIDRVRWSVSAEEVEKNAVVVCIFIKEDVNEAQSSYHL
LLAGFLPTQMIKLKTGNISFGIEQLLYGGGLWGYLEQLQASANYHQFQQSPPIYQYKPQPELLSKINQTQSIKPALFTGI
KNILPYRQQEAINIDYIKIGDECFAQGEYTASIKNYSQALQASSDNCELYYKRGLSYYQLGDYEAAIADYSQAININLHD
AKSYHKRGLALSQLAAYEAAIDDYNQAIRINPHAASIYKNRAEARSHLGDNQGAIEDYTQAIKINPQYADTYKNRGISRY
LLATQPGFTQAIKINPNDANAYKNRGNARADIGDYLGAIEDYNQAIQINPKAADAYYNRGNARYDLGDEEGAIADYTQAI
QINPSYADAYYNRGNVRAGIKDKQGAIADFQKAADIYRKEGKLAELKDTTERVVELEIEESIDILNF
>Mature_547_residues
MDWITLLRSLQSDFIKRLSSGCLLHCEIEGQYSELTVISGERLKTLRDFCWLMAEKYKRVSPVRDVFISYLKGKLGEEVV
KERLADLITEVDYEKRLGGDGKIDFTLTANPAIGIEVKSRHGNIDRVRWSVSAEEVEKNAVVVCIFIKEDVNEAQSSYHL
LLAGFLPTQMIKLKTGNISFGIEQLLYGGGLWGYLEQLQASANYHQFQQSPPIYQYKPQPELLSKINQTQSIKPALFTGI
KNILPYRQQEAINIDYIKIGDECFAQGEYTASIKNYSQALQASSDNCELYYKRGLSYYQLGDYEAAIADYSQAININLHD
AKSYHKRGLALSQLAAYEAAIDDYNQAIRINPHAASIYKNRAEARSHLGDNQGAIEDYTQAIKINPQYADTYKNRGISRY
LLATQPGFTQAIKINPNDANAYKNRGNARADIGDYLGAIEDYNQAIQINPKAADAYYNRGNARYDLGDEEGAIADYTQAI
QINPSYADAYYNRGNVRAGIKDKQGAIADFQKAADIYRKEGKLAELKDTTERVVELEIEESIDILNF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=258, Percent_Identity=29.4573643410853, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI32307148, Length=258, Percent_Identity=29.4573643410853, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI310123097, Length=276, Percent_Identity=25.3623188405797, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310131789, Length=276, Percent_Identity=25.3623188405797, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310110582, Length=276, Percent_Identity=25.3623188405797, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI170784867, Length=254, Percent_Identity=24.4094488188976, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI224809432, Length=230, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI225735591, Length=255, Percent_Identity=29.8039215686275, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI225735593, Length=255, Percent_Identity=29.8039215686275, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI5803181, Length=280, Percent_Identity=24.2857142857143, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=268, Percent_Identity=28.7313432835821, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532690, Length=268, Percent_Identity=28.7313432835821, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17647755, Length=253, Percent_Identity=28.8537549407115, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585827, Length=253, Percent_Identity=28.8537549407115, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585829, Length=253, Percent_Identity=28.8537549407115, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24656717, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI18110006, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 61679; Mature: 61679

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWITLLRSLQSDFIKRLSSGCLLHCEIEGQYSELTVISGERLKTLRDFCWLMAEKYKRV
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
SPVRDVFISYLKGKLGEEVVKERLADLITEVDYEKRLGGDGKIDFTLTANPAIGIEVKSR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEEECCCEEEEEEECC
HGNIDRVRWSVSAEEVEKNAVVVCIFIKEDVNEAQSSYHLLLAGFLPTQMIKLKTGNISF
CCCCEEEEEECCHHHHCCCEEEEEEEEECCHHHHHHHHEEEEEHHCCCEEEEEECCCCCH
GIEQLLYGGGLWGYLEQLQASANYHQFQQSPPIYQYKPQPELLSKINQTQSIKPALFTGI
HHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCEEECCCHHHHHHHCCCCCCCHHHHHHH
KNILPYRQQEAINIDYIKIGDECFAQGEYTASIKNYSQALQASSDNCELYYKRGLSYYQL
HHHCCCCCCCCCEEEEEEECHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEECCCCEEEC
GDYEAAIADYSQAININLHDAKSYHKRGLALSQLAAYEAAIDDYNQAIRINPHAASIYKN
CCHHHHHHCCHHEEEEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
RAEARSHLGDNQGAIEDYTQAIKINPQYADTYKNRGISRYLLATQPGFTQAIKINPNDAN
HHHHHHHCCCCCCCHHHHHHEEEECCCHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCH
AYKNRGNARADIGDYLGAIEDYNQAIQINPKAADAYYNRGNARYDLGDEEGAIADYTQAI
HHHCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCEECCCCCCCCHHCCEEEE
QINPSYADAYYNRGNVRAGIKDKQGAIADFQKAADIYRKEGKLAELKDTTERVVELEIEE
EECCCHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHEEEEHHH
SIDILNF
CCCCCCC
>Mature Secondary Structure
MDWITLLRSLQSDFIKRLSSGCLLHCEIEGQYSELTVISGERLKTLRDFCWLMAEKYKRV
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
SPVRDVFISYLKGKLGEEVVKERLADLITEVDYEKRLGGDGKIDFTLTANPAIGIEVKSR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEEECCCEEEEEEECC
HGNIDRVRWSVSAEEVEKNAVVVCIFIKEDVNEAQSSYHLLLAGFLPTQMIKLKTGNISF
CCCCEEEEEECCHHHHCCCEEEEEEEEECCHHHHHHHHEEEEEHHCCCEEEEEECCCCCH
GIEQLLYGGGLWGYLEQLQASANYHQFQQSPPIYQYKPQPELLSKINQTQSIKPALFTGI
HHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCEEECCCHHHHHHHCCCCCCCHHHHHHH
KNILPYRQQEAINIDYIKIGDECFAQGEYTASIKNYSQALQASSDNCELYYKRGLSYYQL
HHHCCCCCCCCCEEEEEEECHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEECCCCEEEC
GDYEAAIADYSQAININLHDAKSYHKRGLALSQLAAYEAAIDDYNQAIRINPHAASIYKN
CCHHHHHHCCHHEEEEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
RAEARSHLGDNQGAIEDYTQAIKINPQYADTYKNRGISRYLLATQPGFTQAIKINPNDAN
HHHHHHHCCCCCCCHHHHHHEEEECCCHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCH
AYKNRGNARADIGDYLGAIEDYNQAIQINPKAADAYYNRGNARYDLGDEEGAIADYTQAI
HHHCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCEECCCCCCCCHHCCEEEE
QINPSYADAYYNRGNVRAGIKDKQGAIADFQKAADIYRKEGKLAELKDTTERVVELEIEE
EECCCHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHEEEEHHH
SIDILNF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]