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The map label for this gene is yghZ [C]

Identifier: 17227796

GI number: 17227796

Start: 340821

End: 341831

Strand: Direct

Name: yghZ [C]

Synonym: alr0300

Alternate gene names: 17227796

Gene position: 340821-341831 (Clockwise)

Preceding gene: 17227795

Following gene: 17227797

Centisome position: 5.31

GC content: 43.42

Gene sequence:

>1011_bases
GTGCATACAAGAGATCGACAGAGGTTAACAATGCAAATTCACCAAGAACTATCCCTTCCTGGCATGGGTTGTGGAACTTG
GGCGTGGGGAAACCAATTGCTTTGGGGATATAACGAAAGCATGGACGCGCAATTACAAGCTGTCTTTAACCTCTGTGTAA
GTAATGGTGTTACCTTGTTTGATACGGGAGATTCTTACGGCACGGGAAGATTAAATGGGCGTAGTGAGTTGCTGCTGGGG
AAATTTTCTCAAGAATATCAAGGTGTCAATCAAGAAAATATTTGTATTGCTACTAAATTGGCGGCTTACCCCTGGCGATG
GACACGCCAATCAATGATAAATGCTTGCAAGTCTTCTGCTCAACGCTTGGGTAGAAATGTTGACTTAGTACAGATGCACT
GGTCAACTGCCAATTATGCGCCTTGGCAAGAAGTAGGGCTATTAGATGGTTTAGCGGATTTGTATGAGCAGGGTTTAGTG
AAGGGTGTGGGACTATCTAATTACGGAACAAAAAGACTGCAACGTGTACATCAGAAGTTTGCAGAGCGAGGAGTACCAAT
TAAGACACTGCAAGTCCAATATTCCTTATTGTCTACCTATCCTGTGACTGAGTTGGGGTTAAAAGACGTTTGTGATGAAC
TGGGGATTAAGCTGATTGCATACAGCCCTTTAGCTTTGGGAATATTAACAGGGAAATATTCAGAAAAAGGCCCGTTTCCA
AGAGGTGTCCGGGGTTTACTGTTGAGACAGTTGTTGCCAGGAGTGCGATCGCTTCTCCAATGTTTACAAGATGTGGCACA
ATCCAGAAATAAAACCATGTCTCAAGTAGCGCTTAACTGGTGTATTGCTAAAGGAACCATGCCCATCCCTGGTGCAAGGT
CTGTCAAACAAGCCCAGGAGAATATCGGTGCGTTAGGTTGGCAATTAAACTCTGGCGAAATAGCCGAGTTAGATAAAGCG
GCTGCTAGTTCTGATAAAAAAATGGTGCAAAATATTTTTCAGACTAAATAA

Upstream 100 bases:

>100_bases
AAAATCAAAGGTTAATTTGTCATTGGTCATTGGTCATCAGTAAACTTCCCCCACCCTATATTCCCCGCTAAACCACAATT
ATCTGATAATGAACTGAAGA

Downstream 100 bases:

>100_bases
AATTCATCATGATGAACTAAATAAAATTGAATAATATTTAGTACAAAATTACTACAAAAAAGGCGATCGCCTTCCTCCAG
ATATTCCCCGCAAATTCCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MHTRDRQRLTMQIHQELSLPGMGCGTWAWGNQLLWGYNESMDAQLQAVFNLCVSNGVTLFDTGDSYGTGRLNGRSELLLG
KFSQEYQGVNQENICIATKLAAYPWRWTRQSMINACKSSAQRLGRNVDLVQMHWSTANYAPWQEVGLLDGLADLYEQGLV
KGVGLSNYGTKRLQRVHQKFAERGVPIKTLQVQYSLLSTYPVTELGLKDVCDELGIKLIAYSPLALGILTGKYSEKGPFP
RGVRGLLLRQLLPGVRSLLQCLQDVAQSRNKTMSQVALNWCIAKGTMPIPGARSVKQAQENIGALGWQLNSGEIAELDKA
AASSDKKMVQNIFQTK

Sequences:

>Translated_336_residues
MHTRDRQRLTMQIHQELSLPGMGCGTWAWGNQLLWGYNESMDAQLQAVFNLCVSNGVTLFDTGDSYGTGRLNGRSELLLG
KFSQEYQGVNQENICIATKLAAYPWRWTRQSMINACKSSAQRLGRNVDLVQMHWSTANYAPWQEVGLLDGLADLYEQGLV
KGVGLSNYGTKRLQRVHQKFAERGVPIKTLQVQYSLLSTYPVTELGLKDVCDELGIKLIAYSPLALGILTGKYSEKGPFP
RGVRGLLLRQLLPGVRSLLQCLQDVAQSRNKTMSQVALNWCIAKGTMPIPGARSVKQAQENIGALGWQLNSGEIAELDKA
AASSDKKMVQNIFQTK
>Mature_336_residues
MHTRDRQRLTMQIHQELSLPGMGCGTWAWGNQLLWGYNESMDAQLQAVFNLCVSNGVTLFDTGDSYGTGRLNGRSELLLG
KFSQEYQGVNQENICIATKLAAYPWRWTRQSMINACKSSAQRLGRNVDLVQMHWSTANYAPWQEVGLLDGLADLYEQGLV
KGVGLSNYGTKRLQRVHQKFAERGVPIKTLQVQYSLLSTYPVTELGLKDVCDELGIKLIAYSPLALGILTGKYSEKGPFP
RGVRGLLLRQLLPGVRSLLQCLQDVAQSRNKTMSQVALNWCIAKGTMPIPGARSVKQAQENIGALGWQLNSGEIAELDKA
AASSDKKMVQNIFQTK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=322, Percent_Identity=25.776397515528, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4504825, Length=322, Percent_Identity=25.776397515528, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=24.9190938511327, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=24.6913580246914, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789375, Length=331, Percent_Identity=27.7945619335347, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788081, Length=316, Percent_Identity=29.4303797468354, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=26.3929618768328, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081735, Length=283, Percent_Identity=25.4416961130742, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788070, Length=345, Percent_Identity=24.0579710144928, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325384, Length=286, Percent_Identity=23.7762237762238, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37268; Mature: 37268

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTRDRQRLTMQIHQELSLPGMGCGTWAWGNQLLWGYNESMDAQLQAVFNLCVSNGVTLF
CCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEE
DTGDSYGTGRLNGRSELLLGKFSQEYQGVNQENICIATKLAAYPWRWTRQSMINACKSSA
ECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHH
QRLGRNVDLVQMHWSTANYAPWQEVGLLDGLADLYEQGLVKGVGLSNYGTKRLQRVHQKF
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AERGVPIKTLQVQYSLLSTYPVTELGLKDVCDELGIKLIAYSPLALGILTGKYSEKGPFP
HHCCCCEEHHHHHHHHHHCCCCHHHCHHHHHHHHCCEEEEECCHHHHHHCCCCCCCCCCC
RGVRGLLLRQLLPGVRSLLQCLQDVAQSRNKTMSQVALNWCIAKGTMPIPGARSVKQAQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
NIGALGWQLNSGEIAELDKAAASSDKKMVQNIFQTK
HHHHHCEECCCCCHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MHTRDRQRLTMQIHQELSLPGMGCGTWAWGNQLLWGYNESMDAQLQAVFNLCVSNGVTLF
CCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEE
DTGDSYGTGRLNGRSELLLGKFSQEYQGVNQENICIATKLAAYPWRWTRQSMINACKSSA
ECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHH
QRLGRNVDLVQMHWSTANYAPWQEVGLLDGLADLYEQGLVKGVGLSNYGTKRLQRVHQKF
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AERGVPIKTLQVQYSLLSTYPVTELGLKDVCDELGIKLIAYSPLALGILTGKYSEKGPFP
HHCCCCEEHHHHHHHHHHCCCCHHHCHHHHHHHHCCEEEEECCHHHHHHCCCCCCCCCCC
RGVRGLLLRQLLPGVRSLLQCLQDVAQSRNKTMSQVALNWCIAKGTMPIPGARSVKQAQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
NIGALGWQLNSGEIAELDKAAASSDKKMVQNIFQTK
HHHHHCEECCCCCHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]