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The map label for this gene is ndhE

Identifier: 17227722

GI number: 17227722

Start: 242311

End: 242616

Strand: Direct

Name: ndhE

Synonym: alr0226

Alternate gene names: 17227722

Gene position: 242311-242616 (Clockwise)

Preceding gene: 17227721

Following gene: 17227723

Centisome position: 3.78

GC content: 41.83

Gene sequence:

>306_bases
ATGCAACTTCGGTACTTTTTATTACTTGCAGCAGCTTTATTTTGCATTGGCATTTATGGTTTGATTACCAGCCGTAACGC
TGTACGCGTGTTGATGTCAATTGAATTATTGCTGAATGCTGTTAATCTGAATTTAATGGCATTTTCCAACTATCTTGACT
CAACATTAATTAAGGGTCAGGTTTTCACAGTGTTTGTGATTACCGTGGCAGCTGCTGAAGCGGCGGTTGGTCTAGCGATC
GTGCTGGCCATTTATCGCAACCGCGATACCGTCGATATGGAGCAGTTTAATCTCCTGAAATGGTAA

Upstream 100 bases:

>100_bases
GTGTTGACATTACCAGAACGCCCCAGAGAATTAGTAGGTGCTGGTAGCGAAACTCAAGAGTAACAACAAGCCAGATTTTT
CACAAGGAAGACAAAGATTC

Downstream 100 bases:

>100_bases
TTGCGTGTGCAACTCAAGCAGGTAATCATTGCTTATAAGGCGCGAGATTCCCAAAGCAAACGTTGGGCAGAACTCTGCGC
CAAGCAGCTAGAAAATCGCA

Product: NADH dehydrogenase subunit K

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit 4L; NADH-plastoquinone oxidoreductase subunit 4L; NDH-1, subunit 4L; NDH-E

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MQLRYFLLLAAALFCIGIYGLITSRNAVRVLMSIELLLNAVNLNLMAFSNYLDSTLIKGQVFTVFVITVAAAEAAVGLAI
VLAIYRNRDTVDMEQFNLLKW

Sequences:

>Translated_101_residues
MQLRYFLLLAAALFCIGIYGLITSRNAVRVLMSIELLLNAVNLNLMAFSNYLDSTLIKGQVFTVFVITVAAAEAAVGLAI
VLAIYRNRDTVDMEQFNLLKW
>Mature_101_residues
MQLRYFLLLAAALFCIGIYGLITSRNAVRVLMSIELLLNAVNLNLMAFSNYLDSTLIKGQVFTVFVITVAAAEAAVGLAI
VLAIYRNRDTVDMEQFNLLKW

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG0713

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4L family

Homologues:

Organism=Escherichia coli, GI1788615, Length=100, Percent_Identity=34, Blast_Score=65, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU4LC_NOSS1 (Q9WWM4)

Other databases:

- EMBL:   AJ242867
- EMBL:   BA000019
- PIR:   AB1835
- RefSeq:   NP_484270.1
- STRING:   Q9WWM4
- GeneID:   1103823
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr0226
- NMPDR:   fig|103690.1.peg.537
- eggNOG:   COG0713
- HOGENOM:   HBG673066
- OMA:   VLMSIEL
- ProtClustDB:   PRK05715
- BioCyc:   NSP103690:ALR0226-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01456
- InterPro:   IPR001133
- PANTHER:   PTHR11434

Pfam domain/function: PF00420 Oxidored_q2

EC number: 1.6.5.3

Molecular weight: Translated: 11261; Mature: 11261

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc33065c)-; HASH(0xcdc1d44)-; HASH(0xcb8d7c4)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRYFLLLAAALFCIGIYGLITSRNAVRVLMSIELLLNAVNLNLMAFSNYLDSTLIKGQ
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VFTVFVITVAAAEAAVGLAIVLAIYRNRDTVDMEQFNLLKW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCH
>Mature Secondary Structure
MQLRYFLLLAAALFCIGIYGLITSRNAVRVLMSIELLLNAVNLNLMAFSNYLDSTLIKGQ
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VFTVFVITVAAAEAAVGLAIVLAIYRNRDTVDMEQFNLLKW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840