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The map label for this gene is dppB [H]

Identifier: 17227637

GI number: 17227637

Start: 146423

End: 147448

Strand: Direct

Name: dppB [H]

Synonym: alr0141

Alternate gene names: 17227637

Gene position: 146423-147448 (Clockwise)

Preceding gene: 17227636

Following gene: 17227638

Centisome position: 2.28

GC content: 43.08

Gene sequence:

>1026_bases
ATGTCTCGCTCCAAAGCCTTACAATACTACATTGTTTCTCGGTTACTGTTTGCGCCCCTGCAACTGCTAACTATTATTAC
GATTGTATTTTTATTACTCAGAGCTACACCGGGTGACCCAGTAGATGCGATTCTTGGTGGGCGTGCTTCAGAAAGCGTGA
AAGAACAATATCGAGAACAACTGGGTTTAAACCGACCTTTATTTATACAGTACCTAAATTACTTGGGTGATTTACTGCAT
TTTGATTTAGGGACATCTTTGACAAGTCGGGGACAACACGTCTGGAATATCATTGGACAATATTTTCCGGCCACAGTCGA
GTTAGCTGTGTTTAGTATGGCGGTAGCTTTGATTGTGGGAATTTTGGTAGGGACGCTTTCCGCTTCTCGTCCGGGAACTT
CATTTGATATTGGCGGACGGTTATTTGGGATTATTACTTATGCACTCCCCATGTTTTGGGCGGGAATGCTGCTACAGTTA
ATTTTTTCCGTGCAGTTGGGTTGGTTTCCCAATTCCAATCGTTTTCCGCCCAATCTTCCACCCCCGCCTACATTCACAGG
TTTATATACAGTTGATAGTTTGCTCAGTGGTAACTTGACACAGTTTTTTACATCTTTGCATCATTTAGCACTCCCTTGTC
TCACCTTAGGAATTTTGCTGAGTGGCATTTTTGAGCGTATTGTCAGAGTCAATTTAAAGCAAACTCTCAAAGCTGATTAT
GTGGAAGCAGCCAGAGCTAGAGGAATTGCGGAAAATAAAATTTTGGTGTCGCACGCCTTAAAAAATGCGCTGATTCCGGT
AATTACTGTTCTAGGATTAACCTTTGCTTCCCTGCTAGGTGGAGCAATTTTAACGGAAGTGACATTTTCCTGGCCTGGGT
TGGCAAATCGGCTATATCAGGCAATCTCCGATCGCGATTATCCCACAGTCCAAGGTGTGCTGGTATTTTTTGGGGCGATC
GTCGTCTCGGCAAGCATTTTAATTGATATTCTCAATGCTTACGTTGACCCACGTATTCGTTATTAA

Upstream 100 bases:

>100_bases
TCTGTCATCTAAATAACTGACTAATCTCTAATGACTATTGATTTTTGACCAATGACCGATGACCAATGACCGATGACCAA
TGACCAATGACTAAACATTT

Downstream 100 bases:

>100_bases
GGAAATTAGTAGTAATAGCCTAGATATTGCTAAATAAAATGCGTGGCTAATAGCTCTTCGCTCTGTGCTTTGATGTTTTT
ACTATGTCTACCCAACCGAT

Product: permease protein of oligopeptide ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSRSKALQYYIVSRLLFAPLQLLTIITIVFLLLRATPGDPVDAILGGRASESVKEQYREQLGLNRPLFIQYLNYLGDLLH
FDLGTSLTSRGQHVWNIIGQYFPATVELAVFSMAVALIVGILVGTLSASRPGTSFDIGGRLFGIITYALPMFWAGMLLQL
IFSVQLGWFPNSNRFPPNLPPPPTFTGLYTVDSLLSGNLTQFFTSLHHLALPCLTLGILLSGIFERIVRVNLKQTLKADY
VEAARARGIAENKILVSHALKNALIPVITVLGLTFASLLGGAILTEVTFSWPGLANRLYQAISDRDYPTVQGVLVFFGAI
VVSASILIDILNAYVDPRIRY

Sequences:

>Translated_341_residues
MSRSKALQYYIVSRLLFAPLQLLTIITIVFLLLRATPGDPVDAILGGRASESVKEQYREQLGLNRPLFIQYLNYLGDLLH
FDLGTSLTSRGQHVWNIIGQYFPATVELAVFSMAVALIVGILVGTLSASRPGTSFDIGGRLFGIITYALPMFWAGMLLQL
IFSVQLGWFPNSNRFPPNLPPPPTFTGLYTVDSLLSGNLTQFFTSLHHLALPCLTLGILLSGIFERIVRVNLKQTLKADY
VEAARARGIAENKILVSHALKNALIPVITVLGLTFASLLGGAILTEVTFSWPGLANRLYQAISDRDYPTVQGVLVFFGAI
VVSASILIDILNAYVDPRIRY
>Mature_340_residues
SRSKALQYYIVSRLLFAPLQLLTIITIVFLLLRATPGDPVDAILGGRASESVKEQYREQLGLNRPLFIQYLNYLGDLLHF
DLGTSLTSRGQHVWNIIGQYFPATVELAVFSMAVALIVGILVGTLSASRPGTSFDIGGRLFGIITYALPMFWAGMLLQLI
FSVQLGWFPNSNRFPPNLPPPPTFTGLYTVDSLLSGNLTQFFTSLHHLALPCLTLGILLSGIFERIVRVNLKQTLKADYV
EAARARGIAENKILVSHALKNALIPVITVLGLTFASLLGGAILTEVTFSWPGLANRLYQAISDRDYPTVQGVLVFFGAIV
VSASILIDILNAYVDPRIRY

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=335, Percent_Identity=36.7164179104478, Blast_Score=220, Evalue=9e-59,
Organism=Escherichia coli, GI1787761, Length=315, Percent_Identity=40, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1787053, Length=332, Percent_Identity=34.0361445783133, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=33.5766423357664, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789888, Length=334, Percent_Identity=28.7425149700599, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787497, Length=333, Percent_Identity=27.027027027027, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788504, Length=373, Percent_Identity=28.9544235924933, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37471; Mature: 37339

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSKALQYYIVSRLLFAPLQLLTIITIVFLLLRATPGDPVDAILGGRASESVKEQYREQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHH
LGLNRPLFIQYLNYLGDLLHFDLGTSLTSRGQHVWNIIGQYFPATVELAVFSMAVALIVG
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ILVGTLSASRPGTSFDIGGRLFGIITYALPMFWAGMLLQLIFSVQLGWFPNSNRFPPNLP
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PPPTFTGLYTVDSLLSGNLTQFFTSLHHLALPCLTLGILLSGIFERIVRVNLKQTLKADY
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEAARARGIAENKILVSHALKNALIPVITVLGLTFASLLGGAILTEVTFSWPGLANRLYQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AISDRDYPTVQGVLVFFGAIVVSASILIDILNAYVDPRIRY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRSKALQYYIVSRLLFAPLQLLTIITIVFLLLRATPGDPVDAILGGRASESVKEQYREQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHH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HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9680333 [H]