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The map label for this gene is dehH1 [H]

Identifier: 17227535

GI number: 17227535

Start: 40951

End: 41826

Strand: Direct

Name: dehH1 [H]

Synonym: alr0039

Alternate gene names: 17227535

Gene position: 40951-41826 (Clockwise)

Preceding gene: 17227534

Following gene: 17227539

Centisome position: 0.64

GC content: 43.49

Gene sequence:

>876_bases
ATGTTCACCAACTTTGAACAAACCATAGTTGATACAACTGAGGCTCGAATCAATCTAGTCAAAGCTGGTCACGGCGCGCC
ACTACTTTTATTACATGGCTATCCTCAAACTCATGTCATGTGGCATAAGATAGCCCCTCTCCTGGCAAACAATTTTACTG
TAGTCGCAACTGACCTGAGAGGATACGGCGACAGCTCCCGACCTGCAAGCGTCCCCCATCACATCAATTATTCCAAACGA
GTGATGGCGCAAGATCAAGTCGAGGTCATGTCAAAGTTAGGGTATGAACAATTTTATGTGGTCGGTCATGACCGAGGAGC
GCGAGTTGCTCATCGTCTGGCGTTAGATCATCCTCACCGCGTCAAAAAACTAGCCTTACTAGATATTGCGCCCACCCATA
AAATGTACAGGACAACCGATCAAGAGTTTGCCACAGCTTATTATCATTGGTTCTTCCTGATTCAACCCGATAATTTACCA
GAAACCTTAATCGGAGCCAATCCCGAATATTATCTACGTAAATGTTTAGAAAAATGGGGTAAAGATTTTTCAGCTTTTCA
TCCTCAAGCTTTAGCCGAATATATACGGTGCTTTTCTCAGCCTGCTGTAATTCACGCGACCTGTGAAGATTATCGTGCTG
CGGCCACAATTGATTTAGAACATGATGAACTCGACATGAAACAAAAAATTTCGTGTCCAGTGTTGGTTTTGTGGGGAGAG
AAAGGAATTATTGGGCGCAAATATGATGTGTTGGCAACTTGGCGAGAACGGGCAATTGATGTAAGTGGTCAGTCTCTACC
TTGTGGACATTTTCTGCCAGAAGAAGCACCAGAGGAGACTTATCAGGCTATTTATAATTTTTTAACTCACTGTTAA

Upstream 100 bases:

>100_bases
CGACTGGATTACGCCACACCATCCAGTGGTATCTAACTCATCGCCATTGGTGGGAAGCACTTTTACCAAAGGAGTAGGTC
AAGATTGAAAGGGAAAAATC

Downstream 100 bases:

>100_bases
TCCAGTGATTTTTGGGATTGGTAATTGGTAAATGACAAACGAGTTTTAATCTTTACTATCCCTGAGATCATCTAAATTGC
GATCGCCATAACAATAGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MFTNFEQTIVDTTEARINLVKAGHGAPLLLLHGYPQTHVMWHKIAPLLANNFTVVATDLRGYGDSSRPASVPHHINYSKR
VMAQDQVEVMSKLGYEQFYVVGHDRGARVAHRLALDHPHRVKKLALLDIAPTHKMYRTTDQEFATAYYHWFFLIQPDNLP
ETLIGANPEYYLRKCLEKWGKDFSAFHPQALAEYIRCFSQPAVIHATCEDYRAAATIDLEHDELDMKQKISCPVLVLWGE
KGIIGRKYDVLATWRERAIDVSGQSLPCGHFLPEEAPEETYQAIYNFLTHC

Sequences:

>Translated_291_residues
MFTNFEQTIVDTTEARINLVKAGHGAPLLLLHGYPQTHVMWHKIAPLLANNFTVVATDLRGYGDSSRPASVPHHINYSKR
VMAQDQVEVMSKLGYEQFYVVGHDRGARVAHRLALDHPHRVKKLALLDIAPTHKMYRTTDQEFATAYYHWFFLIQPDNLP
ETLIGANPEYYLRKCLEKWGKDFSAFHPQALAEYIRCFSQPAVIHATCEDYRAAATIDLEHDELDMKQKISCPVLVLWGE
KGIIGRKYDVLATWRERAIDVSGQSLPCGHFLPEEAPEETYQAIYNFLTHC
>Mature_291_residues
MFTNFEQTIVDTTEARINLVKAGHGAPLLLLHGYPQTHVMWHKIAPLLANNFTVVATDLRGYGDSSRPASVPHHINYSKR
VMAQDQVEVMSKLGYEQFYVVGHDRGARVAHRLALDHPHRVKKLALLDIAPTHKMYRTTDQEFATAYYHWFFLIQPDNLP
ETLIGANPEYYLRKCLEKWGKDFSAFHPQALAEYIRCFSQPAVIHATCEDYRAAATIDLEHDELDMKQKISCPVLVLWGE
KGIIGRKYDVLATWRERAIDVSGQSLPCGHFLPEEAPEETYQAIYNFLTHC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=289, Percent_Identity=28.3737024221453, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13376164, Length=289, Percent_Identity=28.3737024221453, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI218777837, Length=292, Percent_Identity=26.7123287671233, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI27597073, Length=114, Percent_Identity=35.0877192982456, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=293, Percent_Identity=26.962457337884, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562298, Length=246, Percent_Identity=22.3577235772358, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 33293; Mature: 33293

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTNFEQTIVDTTEARINLVKAGHGAPLLLLHGYPQTHVMWHKIAPLLANNFTVVATDLR
CCCCHHHHHHHCCHHEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECC
GYGDSSRPASVPHHINYSKRVMAQDQVEVMSKLGYEQFYVVGHDRGARVAHRLALDHPHR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCHH
VKKLALLDIAPTHKMYRTTDQEFATAYYHWFFLIQPDNLPETLIGANPEYYLRKCLEKWG
HHHEEEEECCCCHHHHHCCHHHHHEEEEEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHC
KDFSAFHPQALAEYIRCFSQPAVIHATCEDYRAAATIDLEHDELDMKQKISCPVLVLWGE
CCHHCCCHHHHHHHHHHHCCCCEEEEEHHCCCEEEEEECCCCCCCHHHHCCCCEEEEECC
KGIIGRKYDVLATWRERAIDVSGQSLPCGHFLPEEAPEETYQAIYNFLTHC
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTNFEQTIVDTTEARINLVKAGHGAPLLLLHGYPQTHVMWHKIAPLLANNFTVVATDLR
CCCCHHHHHHHCCHHEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECC
GYGDSSRPASVPHHINYSKRVMAQDQVEVMSKLGYEQFYVVGHDRGARVAHRLALDHPHR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCHH
VKKLALLDIAPTHKMYRTTDQEFATAYYHWFFLIQPDNLPETLIGANPEYYLRKCLEKWG
HHHEEEEECCCCHHHHHCCHHHHHEEEEEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHC
KDFSAFHPQALAEYIRCFSQPAVIHATCEDYRAAATIDLEHDELDMKQKISCPVLVLWGE
CCHHCCCHHHHHHHHHHHCCCCEEEEEHHCCCEEEEEECCCCCCCHHHHCCCCEEEEECC
KGIIGRKYDVLATWRERAIDVSGQSLPCGHFLPEEAPEETYQAIYNFLTHC
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512562 [H]