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The map label for this gene is menC [H]

Identifier: 17227530

GI number: 17227530

Start: 34486

End: 35448

Strand: Direct

Name: menC [H]

Synonym: alr0034

Alternate gene names: 17227530

Gene position: 34486-35448 (Clockwise)

Preceding gene: 17227529

Following gene: 17227531

Centisome position: 0.54

GC content: 45.28

Gene sequence:

>963_bases
GTGTTTCCCAATTATGAATTCAGCTTTCGCCCCATAGCCCGAAAATTTGTGCGATCGCTCGTTACTAGTCATGGTATCTG
GGAAGTGCGCGAGGCGATTATTCTCCGGCTTACAGATACCACAGGTAAAGTCGGCTGGGGAGAAATAGCACCGATTAGCT
GGTTTGGATCGGAAACGTTAGCACAGGCTTTAGATTTTTGTCGCCAATTACCAGAAGAAATCACCCAAGAAATCATTTTT
TCCATTCCCGATGATTTACCAGCGTGTCAATTTGGCTTTGAGTCGGCGTTGGAAGCAATGGGGAGTGGTGAAGATGTAAC
TATAACTAACGCTCAATTTAGCGCCTTGTTACCAGCCGGAGAAGCAGCATTACATCAATGGCAAAGTTTATGGGACGAAG
GATATCGCACCTTTAAATGGAAAATTGCCGTGGGTGAAGTCGCCCAAGAATTGAGAATTTTTGACTCCCTAACACAAATT
TTACCTGCATCCGCAAAACTGCGATTAGATGCTAATGGAGGACTGAGTTATCCAGAAGCTCACTTATGGTTACAGGCTTG
TGATAATTTACCCGTAGAAGTGGAATTTATCGAACAACCCCTACCCGTGGAGCAATTTTCCCAGATGTTGGAATTGAGTG
AAGCTTATCCTACAGCGATCGCTTTAGATGAATCTGTAGCTAACCTCAAACAACTAGCTGCTTGTTATGCACAGGGTTGG
CGGGACGTATTTGTGATTAAACCGGCGATCGCTGGTTCACCCTCTCGCCTGCGACAATTTTGCCAACAGCATGAGATTGA
CGCGGTATTCTCATCGGTATTTGAAACGGCGATCGCCAGAAAAGCATCACTCCAACTAGCAGCAGAATTATCTCGTGACA
ACAGGGCTGTTGGTTTTGGCGTTAACCACCTTTTTCACCAAGAAGCAGAAAACTGGCTGCAAAGTTTATGGAACAACCCT
TAG

Upstream 100 bases:

>100_bases
AAAAAGTCAGCAATTGTAAATTCATCGCCGTAGCCGTTCATTTCTGGAGTTGCTTATTACTAGGTTTGGGATTTGTCATT
GCAGGGGTTTAATACTTATT

Downstream 100 bases:

>100_bases
CCTATCTGAATCGCCTCACTCACCATGATTGGCTGATTGGTTATGACAGCCGAGAATTTCACCAAAAAGCCACCGAACTC
TACTTACAACTTAGTCAATT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MFPNYEFSFRPIARKFVRSLVTSHGIWEVREAIILRLTDTTGKVGWGEIAPISWFGSETLAQALDFCRQLPEEITQEIIF
SIPDDLPACQFGFESALEAMGSGEDVTITNAQFSALLPAGEAALHQWQSLWDEGYRTFKWKIAVGEVAQELRIFDSLTQI
LPASAKLRLDANGGLSYPEAHLWLQACDNLPVEVEFIEQPLPVEQFSQMLELSEAYPTAIALDESVANLKQLAACYAQGW
RDVFVIKPAIAGSPSRLRQFCQQHEIDAVFSSVFETAIARKASLQLAAELSRDNRAVGFGVNHLFHQEAENWLQSLWNNP

Sequences:

>Translated_320_residues
MFPNYEFSFRPIARKFVRSLVTSHGIWEVREAIILRLTDTTGKVGWGEIAPISWFGSETLAQALDFCRQLPEEITQEIIF
SIPDDLPACQFGFESALEAMGSGEDVTITNAQFSALLPAGEAALHQWQSLWDEGYRTFKWKIAVGEVAQELRIFDSLTQI
LPASAKLRLDANGGLSYPEAHLWLQACDNLPVEVEFIEQPLPVEQFSQMLELSEAYPTAIALDESVANLKQLAACYAQGW
RDVFVIKPAIAGSPSRLRQFCQQHEIDAVFSSVFETAIARKASLQLAAELSRDNRAVGFGVNHLFHQEAENWLQSLWNNP
>Mature_320_residues
MFPNYEFSFRPIARKFVRSLVTSHGIWEVREAIILRLTDTTGKVGWGEIAPISWFGSETLAQALDFCRQLPEEITQEIIF
SIPDDLPACQFGFESALEAMGSGEDVTITNAQFSALLPAGEAALHQWQSLWDEGYRTFKWKIAVGEVAQELRIFDSLTQI
LPASAKLRLDANGGLSYPEAHLWLQACDNLPVEVEFIEQPLPVEQFSQMLELSEAYPTAIALDESVANLKQLAACYAQGW
RDVFVIKPAIAGSPSRLRQFCQQHEIDAVFSSVFETAIARKASLQLAAELSRDNRAVGFGVNHLFHQEAENWLQSLWNNP

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35849; Mature: 35849

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPNYEFSFRPIARKFVRSLVTSHGIWEVREAIILRLTDTTGKVGWGEIAPISWFGSETL
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCCCCCCCCCCHHCCHHHH
AQALDFCRQLPEEITQEIIFSIPDDLPACQFGFESALEAMGSGEDVTITNAQFSALLPAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCC
EAALHQWQSLWDEGYRTFKWKIAVGEVAQELRIFDSLTQILPASAKLRLDANGGLSYPEA
HHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
HLWLQACDNLPVEVEFIEQPLPVEQFSQMLELSEAYPTAIALDESVANLKQLAACYAQGW
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
RDVFVIKPAIAGSPSRLRQFCQQHEIDAVFSSVFETAIARKASLQLAAELSRDNRAVGFG
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
VNHLFHQEAENWLQSLWNNP
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFPNYEFSFRPIARKFVRSLVTSHGIWEVREAIILRLTDTTGKVGWGEIAPISWFGSETL
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCCCCCCCCCCHHCCHHHH
AQALDFCRQLPEEITQEIIFSIPDDLPACQFGFESALEAMGSGEDVTITNAQFSALLPAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCC
EAALHQWQSLWDEGYRTFKWKIAVGEVAQELRIFDSLTQILPASAKLRLDANGGLSYPEA
HHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
HLWLQACDNLPVEVEFIEQPLPVEQFSQMLELSEAYPTAIALDESVANLKQLAACYAQGW
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
RDVFVIKPAIAGSPSRLRQFCQQHEIDAVFSSVFETAIARKASLQLAAELSRDNRAVGFG
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
VNHLFHQEAENWLQSLWNNP
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]