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The map label for this gene is avtA [H]

Identifier: 161353747

GI number: 161353747

Start: 3420686

End: 3421969

Strand: Direct

Name: avtA [H]

Synonym: alr2811

Alternate gene names: 161353747

Gene position: 3420686-3421969 (Clockwise)

Preceding gene: 17230301

Following gene: 17230304

Centisome position: 53.33

GC content: 45.95

Gene sequence:

>1284_bases
ATGAACCCTGCCCTAACTAAAATTGGCGATCAAATGTCCAACCTGACTGGTGTACGAGCGATTATGAAGGACATTATCGA
AACGTTGAAGTCTGGTGGAGGGCAGGATTTAATTAATTTGAGTGCGGGGAACCCGTTGATTTTGCCAGAGGTAGAACAGT
TATGGCGGGACTGCACAGCAGAACTCTTAGCAAGTCAAGAATATGGTGAAGTAGTTTGTCGCTATGGTTCTAGTCAAGGC
TATGCGCCATTAATTGAAGCGGTTGTGAAAGATTTTAACCGTCGCTATGGTCTGAATTTAACCGATCGCAACATCTTAAT
CACTCCGGGTAGTCAAACTCTGTACTTTTATGCTGCTAATGTTTTCGGCGGTTACACCAGTAGCGGCGACCTCAAGCAAA
TTGTTTTACCCCTGAGTCCCGATTACACTGGCTACGGTGGTATTTGTCTAGTTCCCGAAGCTTTAGTTGCTTACAAACCT
TCTCTAGATATTGATGCAGCAGCACACAGCTTTAAATATCGCCCCGATTTTAGCCAAGTGTCTATTTCCGAAAGCACCGG
CTGCGTCATTTTCTCCCGCCCCTGTAACCCTACAGGCAACGTCCTCACAGATGACGAAGTGAGAAAAATTGCCGCCCTTG
CCGCACCTTATAATGTGCCAGTGCTGATTGATTCGGCTTACGCTCCCCCATTCCCGGCGTTGAACTTCACGGATATGTCG
CTGATTTTTGGGGAAAATATTCTTCATTGCACCAGCTTATCGAAAGCGGGTTTACCAGGGGAGAGAATTGGTATTGCTAT
CGGTAATGAAAGATTAATTCAAGTCCTAGAATCTTTCCAGACTAATGCTAGTTTACATTCCTCACGCTATGGGCAGGCGA
TCGCCGCTCGTGCCATTAACTCTGGTGCGTTGGCACAAATCGCGGAACAAGTTATCCGTCCCTTCTACAAAAACAAATTC
GCCATCGTCGAGAATGCCTTAGAAGCAGCCATGCCCAAAGAATTACCTTGGTTCCTCCATCGTGGTGAAGGTGCTATCTT
TAGTTGGCTATGGTTACAAGATTTGCCCATCACAGATTGGGAATTATACCAAGAACTCAAAAAAGTTGGGGTAATTGTCG
TCCCTGGTAGTACATTCTTCCCTGGCTTAAAAGAAGAATGGGCGCACAAACACCAATGTGTCCGCATCAGCTTGACTGGT
AGCGATACTGAAATCGCCCTTGGTATGCAGCGTCTAGCAAAAGCAGTCGAACAAATTTACCAGCGTACACCCATTAGTGC
TTAA

Upstream 100 bases:

>100_bases
GTACATTAGTTACAGGCGGCAAGCCTAGAAAATGATATTGGTCTGCTGCACTAGACTCATATTTTTGTCAACCCTTCAAT
TATCTTTACTGTTAAAGCTT

Downstream 100 bases:

>100_bases
GTAATGAAGCGTAAACAAGAAAGTAAAGGGGCAGGGGAGAAGAGGCAGGGAGCAGGGGGCAGGGGGCAGGGGGAGAAGAA
GCAGGGGAAGCAGGGGAGGC

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNPALTKIGDQMSNLTGVRAIMKDIIETLKSGGGQDLINLSAGNPLILPEVEQLWRDCTAELLASQEYGEVVCRYGSSQG
YAPLIEAVVKDFNRRYGLNLTDRNILITPGSQTLYFYAANVFGGYTSSGDLKQIVLPLSPDYTGYGGICLVPEALVAYKP
SLDIDAAAHSFKYRPDFSQVSISESTGCVIFSRPCNPTGNVLTDDEVRKIAALAAPYNVPVLIDSAYAPPFPALNFTDMS
LIFGENILHCTSLSKAGLPGERIGIAIGNERLIQVLESFQTNASLHSSRYGQAIAARAINSGALAQIAEQVIRPFYKNKF
AIVENALEAAMPKELPWFLHRGEGAIFSWLWLQDLPITDWELYQELKKVGVIVVPGSTFFPGLKEEWAHKHQCVRISLTG
SDTEIALGMQRLAKAVEQIYQRTPISA

Sequences:

>Translated_427_residues
MNPALTKIGDQMSNLTGVRAIMKDIIETLKSGGGQDLINLSAGNPLILPEVEQLWRDCTAELLASQEYGEVVCRYGSSQG
YAPLIEAVVKDFNRRYGLNLTDRNILITPGSQTLYFYAANVFGGYTSSGDLKQIVLPLSPDYTGYGGICLVPEALVAYKP
SLDIDAAAHSFKYRPDFSQVSISESTGCVIFSRPCNPTGNVLTDDEVRKIAALAAPYNVPVLIDSAYAPPFPALNFTDMS
LIFGENILHCTSLSKAGLPGERIGIAIGNERLIQVLESFQTNASLHSSRYGQAIAARAINSGALAQIAEQVIRPFYKNKF
AIVENALEAAMPKELPWFLHRGEGAIFSWLWLQDLPITDWELYQELKKVGVIVVPGSTFFPGLKEEWAHKHQCVRISLTG
SDTEIALGMQRLAKAVEQIYQRTPISA
>Mature_427_residues
MNPALTKIGDQMSNLTGVRAIMKDIIETLKSGGGQDLINLSAGNPLILPEVEQLWRDCTAELLASQEYGEVVCRYGSSQG
YAPLIEAVVKDFNRRYGLNLTDRNILITPGSQTLYFYAANVFGGYTSSGDLKQIVLPLSPDYTGYGGICLVPEALVAYKP
SLDIDAAAHSFKYRPDFSQVSISESTGCVIFSRPCNPTGNVLTDDEVRKIAALAAPYNVPVLIDSAYAPPFPALNFTDMS
LIFGENILHCTSLSKAGLPGERIGIAIGNERLIQVLESFQTNASLHSSRYGQAIAARAINSGALAQIAEQVIRPFYKNKF
AIVENALEAAMPKELPWFLHRGEGAIFSWLWLQDLPITDWELYQELKKVGVIVVPGSTFFPGLKEEWAHKHQCVRISLTG
SDTEIALGMQRLAKAVEQIYQRTPISA

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=416, Percent_Identity=36.0576923076923, Blast_Score=299, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322401, Length=366, Percent_Identity=22.4043715846995, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46739; Mature: 46739

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPALTKIGDQMSNLTGVRAIMKDIIETLKSGGGQDLINLSAGNPLILPEVEQLWRDCTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECHHHHHHHHHHHH
ELLASQEYGEVVCRYGSSQGYAPLIEAVVKDFNRRYGLNLTDRNILITPGSQTLYFYAAN
HHHHCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEE
VFGGYTSSGDLKQIVLPLSPDYTGYGGICLVPEALVAYKPSLDIDAAAHSFKYRPDFSQV
CCCCCCCCCCCEEEEEECCCCCCCCCCEEECCHHHHHCCCCCCCHHHHHCCCCCCCCCEE
SISESTGCVIFSRPCNPTGNVLTDDEVRKIAALAAPYNVPVLIDSAYAPPFPALNFTDMS
EECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHH
LIFGENILHCTSLSKAGLPGERIGIAIGNERLIQVLESFQTNASLHSSRYGQAIAARAIN
HHHCCCCEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
SGALAQIAEQVIRPFYKNKFAIVENALEAAMPKELPWFLHRGEGAIFSWLWLQDLPITDW
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHEECCCCCEEEEEEEECCCCCHH
ELYQELKKVGVIVVPGSTFFPGLKEEWAHKHQCVRISLTGSDTEIALGMQRLAKAVEQIY
HHHHHHHHCCEEEECCCCCCCCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
QRTPISA
HHCCCCC
>Mature Secondary Structure
MNPALTKIGDQMSNLTGVRAIMKDIIETLKSGGGQDLINLSAGNPLILPEVEQLWRDCTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECHHHHHHHHHHHH
ELLASQEYGEVVCRYGSSQGYAPLIEAVVKDFNRRYGLNLTDRNILITPGSQTLYFYAAN
HHHHCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEE
VFGGYTSSGDLKQIVLPLSPDYTGYGGICLVPEALVAYKPSLDIDAAAHSFKYRPDFSQV
CCCCCCCCCCCEEEEEECCCCCCCCCCEEECCHHHHHCCCCCCCHHHHHCCCCCCCCCEE
SISESTGCVIFSRPCNPTGNVLTDDEVRKIAALAAPYNVPVLIDSAYAPPFPALNFTDMS
EECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHH
LIFGENILHCTSLSKAGLPGERIGIAIGNERLIQVLESFQTNASLHSSRYGQAIAARAIN
HHHCCCCEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
SGALAQIAEQVIRPFYKNKFAIVENALEAAMPKELPWFLHRGEGAIFSWLWLQDLPITDW
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHEECCCCCEEEEEEEECCCCCHH
ELYQELKKVGVIVVPGSTFFPGLKEEWAHKHQCVRISLTGSDTEIALGMQRLAKAVEQIY
HHHHHHHHCCEEEECCCCCCCCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
QRTPISA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]