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The map label for this gene is uxuR [H]

Identifier: 39546359

GI number: 39546359

Start: 3247098

End: 3247847

Strand: Reverse

Name: uxuR [H]

Synonym: STM3084.S

Alternate gene names: 39546359

Gene position: 3247847-3247098 (Counterclockwise)

Preceding gene: 16766386

Following gene: 16766384

Centisome position: 66.86

GC content: 44.93

Gene sequence:

>750_bases
ATGGAACAAATTTTAACCAAGCGGCGCTATTTTGATATAGGGCTGCAAATAGAAGAACTACTCTATTCAGGGGTATTTAA
AGCTGGCGAGCGACTTCCGGCGGAGAGAGAACTCAGCGAGCGTTTTCAAACCAGCCGCACGACGATTCGTGAGGCGATTA
TTATGCTTGAGCTGAAGGGAGTGGTAGAGGTTAAGCAAGGCGCAGGCACTTACTTTATTGATAGTCTGGAAAAAATCAAT
CAAAAAGCGCTCTTGCCTTACTCAGACATTGGCCCCTTTGAATTGCTACAGGCCCGGCAGGTCATCGAAAGTAACATCAC
CGGTTTTGCCGCTACGCAAATCAGATTTAATGAACTTAAGCAGCTTAAACGTATTATTGAGCAGCAGGAAAAGCAGATTG
GCGGCGACAGCGACAAATTTGAAGAACTGGATCGCCAGTTCCACAATATCATCGCGGAATCCACGCAAAATCGTGTATTA
ATGAAACAATCTGCCGAGCTGTGGCGGGCTGTCAGGACCGAAAATCCGCGCTGGAAGCAGTTAAACTATAAGTATTTACA
TAAGAAAGAGTTAAGAATGAAATGGGTGGAAGATCACCGTAGTATCTTCCTTGCATTGCAAAAACGCGATGCTGAGCAGG
CCAGACAGGCTTCGTGGACCCATCTTGAAAACAGTAAAAATGAGCTGGTAAAAATCTTCCAACAGGATGATTCGCTGGAA
GATTTTGATGATTTTTTCTTCGCCACCTGA

Upstream 100 bases:

>100_bases
GAAACGACCACTCTCTGGCAGGGAAATTGTTTACCATAAACATTAGGATTTGTTTACACTACCCTCAAGTGGAGCAATTG
CTGTCTACATAGGTATGTGC

Downstream 100 bases:

>100_bases
CGGCTATTTTCAGGCGGATGACATTTTTGTCAGCGATTAACCGGGCCTGCCGCCAAAAACAAGCCCGGAGAGAGGGAATC
AGGCTTCGTAAACGCTCAGC

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MEQILTKRRYFDIGLQIEELLYSGVFKAGERLPAERELSERFQTSRTTIREAIIMLELKGVVEVKQGAGTYFIDSLEKIN
QKALLPYSDIGPFELLQARQVIESNITGFAATQIRFNELKQLKRIIEQQEKQIGGDSDKFEELDRQFHNIIAESTQNRVL
MKQSAELWRAVRTENPRWKQLNYKYLHKKELRMKWVEDHRSIFLALQKRDAEQARQASWTHLENSKNELVKIFQQDDSLE
DFDDFFFAT

Sequences:

>Translated_249_residues
MEQILTKRRYFDIGLQIEELLYSGVFKAGERLPAERELSERFQTSRTTIREAIIMLELKGVVEVKQGAGTYFIDSLEKIN
QKALLPYSDIGPFELLQARQVIESNITGFAATQIRFNELKQLKRIIEQQEKQIGGDSDKFEELDRQFHNIIAESTQNRVL
MKQSAELWRAVRTENPRWKQLNYKYLHKKELRMKWVEDHRSIFLALQKRDAEQARQASWTHLENSKNELVKIFQQDDSLE
DFDDFFFAT
>Mature_249_residues
MEQILTKRRYFDIGLQIEELLYSGVFKAGERLPAERELSERFQTSRTTIREAIIMLELKGVVEVKQGAGTYFIDSLEKIN
QKALLPYSDIGPFELLQARQVIESNITGFAATQIRFNELKQLKRIIEQQEKQIGGDSDKFEELDRQFHNIIAESTQNRVL
MKQSAELWRAVRTENPRWKQLNYKYLHKKELRMKWVEDHRSIFLALQKRDAEQARQASWTHLENSKNELVKIFQQDDSLE
DFDDFFFAT

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=247, Percent_Identity=39.6761133603239, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI87082208, Length=252, Percent_Identity=37.6984126984127, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786303, Length=214, Percent_Identity=31.3084112149533, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790032, Length=226, Percent_Identity=25.6637168141593, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789353, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI48994955, Length=243, Percent_Identity=26.3374485596708, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787821, Length=204, Percent_Identity=26.9607843137255, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789621, Length=223, Percent_Identity=25.1121076233184, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29451; Mature: 29451

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQILTKRRYFDIGLQIEELLYSGVFKAGERLPAERELSERFQTSRTTIREAIIMLELKG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVEVKQGAGTYFIDSLEKINQKALLPYSDIGPFELLQARQVIESNITGFAATQIRFNELK
HHHHHCCCCHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QLKRIIEQQEKQIGGDSDKFEELDRQFHNIIAESTQNRVLMKQSAELWRAVRTENPRWKQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LNYKYLHKKELRMKWVEDHRSIFLALQKRDAEQARQASWTHLENSKNELVKIFQQDDSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
DFDDFFFAT
HHHHHHCCC
>Mature Secondary Structure
MEQILTKRRYFDIGLQIEELLYSGVFKAGERLPAERELSERFQTSRTTIREAIIMLELKG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVEVKQGAGTYFIDSLEKINQKALLPYSDIGPFELLQARQVIESNITGFAATQIRFNELK
HHHHHCCCCHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QLKRIIEQQEKQIGGDSDKFEELDRQFHNIIAESTQNRVLMKQSAELWRAVRTENPRWKQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LNYKYLHKKELRMKWVEDHRSIFLALQKRDAEQARQASWTHLENSKNELVKIFQQDDSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
DFDDFFFAT
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]