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The map label for this gene is umuD [H]

Identifier: 39546338

GI number: 39546338

Start: 2330961

End: 2331431

Strand: Reverse

Name: umuD [H]

Synonym: STM2230.1c

Alternate gene names: 39546338

Gene position: 2331431-2330961 (Counterclockwise)

Preceding gene: 16765561

Following gene: 16765555

Centisome position: 48.0

GC content: 51.59

Gene sequence:

>471_bases
GTGACAACATTCCGCGATGTATCAACGCAGGAAGGGGAGACGTACCTTTCAGCTGTTCAATCCAAACGGAGGACTATAGC
CATGGGCTTCCCTTCACCTGCCAGTGATTACGTTGAAACAAGGATCTCCCTCGATCAGCAGCTAATCAGCCAGCCCGCAG
CGACTTATTTCATGCGGGCATCGCGTTCACATTTCAGGGAAGGGATAATCCAGGGGGCGCTACTTGTTGTGGACGCGTCG
CTTTCAGCCTGTGATGGCTCGCTGCTGATATGCGCGATAGATGGGGAATTCAGGATCAAGCGATACCGAACTCACCCTCA
GCCCCACCTGATAAATCTGGAGAACGGGAGAAAGGAAGCGCTGCCAGAAGATGGTGATGGCTACAATTCTTCACACGCAA
TATTTGGAGTTATCACGTACATCATTAATGATGCCAGGAACGCGGAGTTTGATGACTGCCCGGTGATGTGA

Upstream 100 bases:

>100_bases
TGGCCGGAAGACCGTCACCACACAGCGGTTTGTCCAGCAACTGAGCAAGGTTAACTGGAACTGGACGATGAAGCAGGCTA
ACGAATGGATCGAGTGGTAT

Downstream 100 bases:

>100_bases
ATAGTTGAAACTTTACGGTAAAGTCGATGTTTTGTGTCGGGGTTTTTCCCCGATTATTCCCCGTTGCTTCCCCGTTCAGA
AAACAGGCATAAAAAAACCA

Product: DNA polymerase V subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTTFRDVSTQEGETYLSAVQSKRRTIAMGFPSPASDYVETRISLDQQLISQPAATYFMRASRSHFREGIIQGALLVVDAS
LSACDGSLLICAIDGEFRIKRYRTHPQPHLINLENGRKEALPEDGDGYNSSHAIFGVITYIINDARNAEFDDCPVM

Sequences:

>Translated_156_residues
MTTFRDVSTQEGETYLSAVQSKRRTIAMGFPSPASDYVETRISLDQQLISQPAATYFMRASRSHFREGIIQGALLVVDAS
LSACDGSLLICAIDGEFRIKRYRTHPQPHLINLENGRKEALPEDGDGYNSSHAIFGVITYIINDARNAEFDDCPVM
>Mature_155_residues
TTFRDVSTQEGETYLSAVQSKRRTIAMGFPSPASDYVETRISLDQQLISQPAATYFMRASRSHFREGIIQGALLVVDASL
SACDGSLLICAIDGEFRIKRYRTHPQPHLINLENGRKEALPEDGDGYNSSHAIFGVITYIINDARNAEFDDCPVM

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=119, Percent_Identity=40.3361344537815, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 17349; Mature: 17218

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFRDVSTQEGETYLSAVQSKRRTIAMGFPSPASDYVETRISLDQQLISQPAATYFMRA
CCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
SRSHFREGIIQGALLVVDASLSACDGSLLICAIDGEFRIKRYRTHPQPHLINLENGRKEA
HHHHHHHHHHHCEEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEECCCCCCCC
LPEDGDGYNSSHAIFGVITYIINDARNAEFDDCPVM
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTFRDVSTQEGETYLSAVQSKRRTIAMGFPSPASDYVETRISLDQQLISQPAATYFMRA
CCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
SRSHFREGIIQGALLVVDASLSACDGSLLICAIDGEFRIKRYRTHPQPHLINLENGRKEA
HHHHHHHHHHHCEEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEECCCCCCCC
LPEDGDGYNSSHAIFGVITYIINDARNAEFDDCPVM
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]