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The map label for this gene is moeA

Identifier: 308065968

GI number: 308065968

Start: 915711

End: 916946

Strand: Reverse

Name: moeA

Synonym: NA

Alternate gene names: 308065968

Gene position: 916946-915711 (Counterclockwise)

Preceding gene: 16764214

Following gene: 16764207

Centisome position: 18.88

GC content: 58.09

Gene sequence:

>1236_bases
ATGGAATTTTCCGCCGGATTGATGCCGCTTGAAACGGCGCTGACCCAGATGCTTTCACGTATTACCCCTCTCACCGCCGT
AGAAACGTTGCCGCTGGTGAACTGCTTTGGCCGCATCCTGGCGACCGATATCGTATCTCCCCTTGATGTCCCCGGCTTTG
ATAATTCAGCTATGGATGGTTATGCGGTACGTGTGGCGGATTTGTCCGCCGATAAGCCGCTGCCCGTCGCCGGCAAAGCA
TTTGCCGGTCAGCCCTACCAGGGAGAGTGGCCTGCGGGAACCTGCATTCGCATTATGACCGGCGCCCCGGTACCGGCAGG
TTGCGAGGCGGTAGTCATGCAAGAGCAGACGGAACAAACCGATGACGGCGTGCGTTTTACCGCCGATGTTCGTTGCGGAC
AAAACATCCGCCGCCGCGGCGAGGATATTCGCCAGGATGCGGTGGTCTTTCCGGCCGGTACGCGCCTGACTACTGCCGAA
CTGCCAGTGCTGGCGTCGCTGGGAATTGCCGATGCGCAGGTTGTACGTAAAGTGCGCGTAGCGCTGTTCTCGACCGGCGA
CGAGCTCCAGCTTCCGGGCCAGCCGCTGGAGGCGGGACAAATTTATGACACTAACCGTCTAACTATACATTTGATGCTGC
AACAGCTTGGCTGCGAAGTGATCAATTTAGGCATTATTCCTGACGATCCCGGTAAGCTTCGCGCCGCGTTTATCGACGCC
GACAGCCAGGCCGATGTAGTGATAAGCTCCGGCGGCGTCTCGGTTGGTGAAGCGGACTATACCAAAACCATCCTTGAGGA
GCTGGGCGAAATCGCCTTCTGGAAGCTGGCTATCAAGCCAGGCAAACCGTTTGCCTTCGGCAAGCTCAGTAATAGCTGGT
TCTGTGGCCTGCCGGGGAATCCAGTCTCTGCGGCGCTCACGTTTTATCAACTGGTTCAGCCCTTACTGGCGAAGCTTGGC
GGCAACACGGCAAGCGCAGTGCCGCCGCGCCAGCGTGTACGCACAGCATCTCGCCTGAAGAAAACGCCGGGGCGTCTCGA
TTTCCAGCGCGGCATTCTGCAACGTAGCGCCAACGGCGAACTGGAGGTCACGACCACCGGACACCAGGGTTCACATATTT
TCAGCTCGTTTAGTCTGGGCAACTGCTTTATTGTGCTGGAGCGTGAACGCGGCAATGTTGAGCCGGGAGAATGGGTGGAA
GTCGAGCCGTTTAATGCTCTGTTCGGAGGCCTGTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: molybdopterin biosynthesis protein MoeA

Products: NA

Alternate protein names: MPT Mo-transferase

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:
NA

Sequences:

>Translated_411_residues
MEFSAGLMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDGYAVRVADLSADKPLPVAGKA
FAGQPYQGEWPAGTCIRIMTGAPVPAGCEAVVMQEQTEQTDDGVRFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAE
LPVLASLGIADAQVVRKVRVALFSTGDELQLPGQPLEAGQIYDTNRLTIHLMLQQLGCEVINLGIIPDDPGKLRAAFIDA
DSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSAALTFYQLVQPLLAKLG
GNTASAVPPRQRVRTASRLKKTPGRLDFQRGILQRSANGELEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWVE
VEPFNALFGGL
>Mature_411_residues
MEFSAGLMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDGYAVRVADLSADKPLPVAGKA
FAGQPYQGEWPAGTCIRIMTGAPVPAGCEAVVMQEQTEQTDDGVRFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAE
LPVLASLGIADAQVVRKVRVALFSTGDELQLPGQPLEAGQIYDTNRLTIHLMLQQLGCEVINLGIIPDDPGKLRAAFIDA
DSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSAALTFYQLVQPLLAKLG
GNTASAVPPRQRVRTASRLKKTPGRLDFQRGILQRSANGELEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWVE
VEPFNALFGGL

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family

Homologues:

Organism=Homo sapiens, GI66932975, Length=414, Percent_Identity=36.231884057971, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI10880983, Length=414, Percent_Identity=36.231884057971, Blast_Score=201, Evalue=1e-51,
Organism=Escherichia coli, GI1787049, Length=411, Percent_Identity=87.5912408759124, Blast_Score=721, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147659, Length=366, Percent_Identity=30.6010928961749, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17562606, Length=222, Percent_Identity=27.9279279279279, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17136978, Length=278, Percent_Identity=33.0935251798561, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24638841, Length=278, Percent_Identity=33.0935251798561, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOEA_SALTY (Q56066)

Other databases:

- EMBL:   U53178
- EMBL:   AE006468
- ProteinModelPortal:   Q56066
- SMR:   Q56066
- PRIDE:   Q56066
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM0846
- NMPDR:   fig|99287.1.peg.810
- HOGENOM:   HBG731522
- OMA:   VPGFDNA
- ProtClustDB:   PRK10680
- BioCyc:   STYP99287:STM0846-MONOMER
- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- SMART:   SM00852
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N; SSF53218 MoCF_biosynth; SSF63867 MoeA_C; SSF63882 MoeA_N

EC number: NA

Molecular weight: Translated: 44065; Mature: 44065

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSAGLMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDG
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
YAVRVADLSADKPLPVAGKAFAGQPYQGEWPAGTCIRIMTGAPVPAGCEAVVMQEQTEQT
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHCCCC
DDGVRFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAELPVLASLGIADAQVVRKVRV
CCCEEEEEECCCCHHHHHCCHHHHHCCEEECCCCEEEECCCCHHHHCCCHHHHHHHHHHH
ALFSTGDELQLPGQPLEAGQIYDTNRLTIHLMLQQLGCEVINLGIIPDDPGKLRAAFIDA
HHCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHCCEEEEEECCCCCCCCEEEEEEEC
DSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGN
CCCCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCCEEECCCCC
PVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVRTASRLKKTPGRLDFQRGILQRSANGE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
LEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWVEVEPFNALFGGL
EEEEECCCCCCHHEEEECCCCEEEEEECCCCCCCCCCEEEECCHHHHHCCC
>Mature Secondary Structure
MEFSAGLMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDG
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
YAVRVADLSADKPLPVAGKAFAGQPYQGEWPAGTCIRIMTGAPVPAGCEAVVMQEQTEQT
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHCCCC
DDGVRFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAELPVLASLGIADAQVVRKVRV
CCCEEEEEECCCCHHHHHCCHHHHHCCEEECCCCEEEECCCCHHHHCCCHHHHHHHHHHH
ALFSTGDELQLPGQPLEAGQIYDTNRLTIHLMLQQLGCEVINLGIIPDDPGKLRAAFIDA
HHCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHCCEEEEEECCCCCCCCEEEEEEEC
DSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGN
CCCCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCCEEECCCCC
PVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVRTASRLKKTPGRLDFQRGILQRSANGE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
LEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWVEVEPFNALFGGL
EEEEECCCCCCHHEEEECCCCEEEEEECCCCCCCCCCEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609