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The map label for this gene is yigW [H]

Identifier: 308065944

GI number: 308065944

Start: 4182134

End: 4182916

Strand: Direct

Name: yigW [H]

Synonym: NA

Alternate gene names: 308065944

Gene position: 4182134-4182916 (Clockwise)

Preceding gene: 16767245

Following gene: 16767248

Centisome position: 86.1

GC content: 54.15

Gene sequence:

>783_bases
ATGTTTGATATTGGCGTTAATTTAACCAGTAGCCAGTTTGCAAAAGATCGTGATGATGTGGTCGCCCGTGCGTTTGCGGC
GGGAGTAAAAGGTATGCTACTGACCGGAACGAACATCCATGAAAGTCAGCAGGCGTTAAAACTGGCGCGGCGCTACCCCC
ATTGTTGGTCGACGGCTGGCGTCCATCCCCATGACAGCAGTCAGTGGTCACCCGCGTCTGAAGACGCCATTATTGCGCTG
GCGAACCAGCCGGAAGTCGTCGCTATCGGTGAGTGCGGGCTGGATTTCAATCGCAATTTTTCCACGCCGCAGGAGCAGGA
GCGTGCCTTTCAGGCGCAGCTACAAATTGCCGCCGAATTGCAGATACCAATCTTTATGCACTGCCGGGACGCGCATGAGC
GATTTCTGGTATTGCTTGATCCCTGGCTGGATAGTCTTCCTGGTGCAATACTGCACTGCTTTACCGGTTCACGCCAGCAA
ATGCAGGCCTGTGTGGATAGAGGGCTCTATATCGGTATTACCGGGTGGGTTTGCGACGAACGACGCGGGCTTGAGCTACG
TGAACTCTTACCGTTTATTCCAGCGGAAAAGCTACTGATAGAAACCGACGCGCCGTATCTGTTGCCTCGCGATCTTACGC
CGAAACCAACGTCACGACGCAACGAGCCCGCGTATCTGCCTCACATCCTGGAGCGCATAGCGCTATGGCGTGGTGAAGAT
CCGCAATGGTTAGCGGCGATGACAGATGCCAACGCCAGAACCTTATTTGAGGTTGTATTCTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: DNase TatD

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:
NA

Sequences:

>Translated_260_residues
MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAGVHPHDSSQWSPASEDAIIAL
ANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAELQIPIFMHCRDAHERFLVLLDPWLDSLPGAILHCFTGSRQQ
MQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALWRGED
PQWLAAMTDANARTLFEVVF
>Mature_260_residues
MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAGVHPHDSSQWSPASEDAIIAL
ANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAELQIPIFMHCRDAHERFLVLLDPWLDSLPGAILHCFTGSRQQ
MQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALWRGED
PQWLAAMTDANARTLFEVVF

Specific function: Shows DNase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=291, Percent_Identity=34.020618556701, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=33.7349397590361, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI225903424, Length=182, Percent_Identity=34.6153846153846, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=27.1375464684015, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=27.1062271062271, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=27.5092936802974, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=81.5384615384615, Blast_Score=453, Evalue=1e-129,
Organism=Escherichia coli, GI1787342, Length=251, Percent_Identity=33.0677290836653, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87082439, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=37.5, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=24.3445692883895, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=170, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543026, Length=171, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=281, Percent_Identity=37.0106761565836, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI221330018, Length=296, Percent_Identity=30.4054054054054, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24586117, Length=268, Percent_Identity=30.5970149253731, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29272; Mature: 29272

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAG
CEEECCCCCHHHHHCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
VHPHDSSQWSPASEDAIIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAEL
CCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEE
QIPIFMHCRDAHERFLVLLDPWLDSLPGAILHCFTGSRQQMQACVDRGLYIGITGWVCDE
CCEEEEEECCCCCEEEEEECHHHHHCCHHEEHHHCCCHHHHHHHHHCCEEEEEEEEEECC
RRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALWRGED
CCCCCHHHHHCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
PQWLAAMTDANARTLFEVVF
CCEEEEECCCCHHHHHEECC
>Mature Secondary Structure
MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQALKLARRYPHCWSTAG
CEEECCCCCHHHHHCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
VHPHDSSQWSPASEDAIIALANQPEVVAIGECGLDFNRNFSTPQEQERAFQAQLQIAAEL
CCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEE
QIPIFMHCRDAHERFLVLLDPWLDSLPGAILHCFTGSRQQMQACVDRGLYIGITGWVCDE
CCEEEEEECCCCCEEEEEECHHHHHCCHHEEHHHCCCHHHHHHHHHCCEEEEEEEEEECC
RRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTSRRNEPAYLPHILERIALWRGED
CCCCCHHHHHCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
PQWLAAMTDANARTLFEVVF
CCEEEEECCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]