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The map label for this gene is frwC [H]

Identifier: 16767377

GI number: 16767377

Start: 4327301

End: 4328380

Strand: Direct

Name: frwC [H]

Synonym: STM4112

Alternate gene names: 16767377

Gene position: 4327301-4328380 (Clockwise)

Preceding gene: 16767372

Following gene: 16767378

Centisome position: 89.09

GC content: 56.85

Gene sequence:

>1080_bases
ATGAAAGAGTTGGTACAGATCCTGAAAAATACCCGCCAGCACCTGATGACCGGTGTTTCGCATATGATCCCCTTTGTGGT
GGCTGGCGGAATTTTGCTGGCAGTCTCCGTCATGCTATATGGCAAGGGCGCCGTACCCGATGCCGCCACCGATCCGAATC
TTAAAAAACTGTTTGATATCGGTGTCGCCGGGCTGACGCTGATGGTGCCTTTCCTCGCCGCATACATCGGTTACTCCATT
GCCGAACGCTCCGCGCTGGCTCCTTGCGCAATTGGTGCCTGGGTGGGTAACAGCTTCGGCGCGGGTTTTTTCGGGGCACT
TATCGCCGGACTTATCGGCGGGATCGTGGTGCATTACTTGAAGAAAATCCCGGTGCATAAGGTGCTGCGTTCTGTGATGC
CTATTTTTGTGATTCCCATCGTTGGCACTTTTATCACCGCGGGCATCATGATGTGGGGGCTGGGCGAACCGATCGGTGCG
CTGACAAGCAGCCTGACCCAATGGCTGCAAGGGATGCAGCAGGGCAGCATCGTGCTGCTGGCGGTGATCATGGGGCTGAT
GCTGGCTTTTGATATGGGCGGCCCGGTTAACAAAGTCGCTTATGCGTTCATGCTGATTTGCGTGGCGCAGGGCGTATATA
CCGTGGTGGCTATCGCCGCGGTGAGCATCTGCGTACCGCCACTGGGACTGGGGCTGGCGACGCTGATTGGCCGCAAGAAT
TTTTCTGTTGAAGAGCGCGAAGCCGGTAAAGCCGCGCTGGTCATGGGCTGCGTGGGCGTAACGGAAGGGGCGATTCCTTT
CGCCGCTGCCGATCCGCTGCGCGTGATCCCATCCATTATGGTGGGCTCCGCTTGCGGTGCGGTAATGGCCGCGCTGTTTG
GCGCGCAGTGTTATGCCGGTTGGGGCGGTTTAATTGTTCTGCCAGTCGTGGAAGGCAAGCTGGGTTATGTCGCGGCAGTC
GCCGTGGGCGCGGTGGTAACGGCAGTCTGCGTTAACGTGCTGAAAAGCCTGACGCGTAAGAATGTGTCGCAAGTTGACGA
AAAAGAAGACGACCTGGATTTAGATTTTGAGATGAATTAA

Upstream 100 bases:

>100_bases
TAAATGGCCTTTTTATCCACTGTCTGCGCGGCAATGGATTGCCTATTGTTTTCCGCAGTAACTTTATGGACATGGGCTTT
ATCCAGCCCGGGAGCGACTT

Downstream 100 bases:

>100_bases
GCGAGGAATAAGCCATGACTAAAATTATTGCAGTAACCGCGTGTCCTTCTGGTGTTGCGCATACCTATATGGCGGCTGAA
GCGCTGGAAAGCGCAGCCAA

Product: fructose-like permease EIIC subunit 2

Products: NA

Alternate protein names: PTS system fructose-like EIIC component 2 [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKELVQILKNTRQHLMTGVSHMIPFVVAGGILLAVSVMLYGKGAVPDAATDPNLKKLFDIGVAGLTLMVPFLAAYIGYSI
AERSALAPCAIGAWVGNSFGAGFFGALIAGLIGGIVVHYLKKIPVHKVLRSVMPIFVIPIVGTFITAGIMMWGLGEPIGA
LTSSLTQWLQGMQQGSIVLLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAIAAVSICVPPLGLGLATLIGRKN
FSVEEREAGKAALVMGCVGVTEGAIPFAAADPLRVIPSIMVGSACGAVMAALFGAQCYAGWGGLIVLPVVEGKLGYVAAV
AVGAVVTAVCVNVLKSLTRKNVSQVDEKEDDLDLDFEMN

Sequences:

>Translated_359_residues
MKELVQILKNTRQHLMTGVSHMIPFVVAGGILLAVSVMLYGKGAVPDAATDPNLKKLFDIGVAGLTLMVPFLAAYIGYSI
AERSALAPCAIGAWVGNSFGAGFFGALIAGLIGGIVVHYLKKIPVHKVLRSVMPIFVIPIVGTFITAGIMMWGLGEPIGA
LTSSLTQWLQGMQQGSIVLLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAIAAVSICVPPLGLGLATLIGRKN
FSVEEREAGKAALVMGCVGVTEGAIPFAAADPLRVIPSIMVGSACGAVMAALFGAQCYAGWGGLIVLPVVEGKLGYVAAV
AVGAVVTAVCVNVLKSLTRKNVSQVDEKEDDLDLDFEMN
>Mature_359_residues
MKELVQILKNTRQHLMTGVSHMIPFVVAGGILLAVSVMLYGKGAVPDAATDPNLKKLFDIGVAGLTLMVPFLAAYIGYSI
AERSALAPCAIGAWVGNSFGAGFFGALIAGLIGGIVVHYLKKIPVHKVLRSVMPIFVIPIVGTFITAGIMMWGLGEPIGA
LTSSLTQWLQGMQQGSIVLLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAIAAVSICVPPLGLGLATLIGRKN
FSVEEREAGKAALVMGCVGVTEGAIPFAAADPLRVIPSIMVGSACGAVMAALFGAQCYAGWGGLIVLPVVEGKLGYVAAV
AVGAVVTAVCVNVLKSLTRKNVSQVDEKEDDLDLDFEMN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=359, Percent_Identity=93.3147632311978, Blast_Score=616, Evalue=1e-178,
Organism=Escherichia coli, GI1788492, Length=328, Percent_Identity=39.3292682926829, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1786951, Length=288, Percent_Identity=38.5416666666667, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87082348, Length=351, Percent_Identity=32.7635327635328, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788729, Length=380, Percent_Identity=27.3684210526316, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013014
- InterPro:   IPR006327 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37237; Mature: 37237

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELVQILKNTRQHLMTGVSHMIPFVVAGGILLAVSVMLYGKGAVPDAATDPNLKKLFDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAGFFGALIAGLIGGIVVHYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KKIPVHKVLRSVMPIFVIPIVGTFITAGIMMWGLGEPIGALTSSLTQWLQGMQQGSIVLL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHH
AVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAIAAVSICVPPLGLGLATLIGRKN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
FSVEEREAGKAALVMGCVGVTEGAIPFAAADPLRVIPSIMVGSACGAVMAALFGAQCYAG
CCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WGGLIVLPVVEGKLGYVAAVAVGAVVTAVCVNVLKSLTRKNVSQVDEKEDDLDLDFEMN
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
>Mature Secondary Structure
MKELVQILKNTRQHLMTGVSHMIPFVVAGGILLAVSVMLYGKGAVPDAATDPNLKKLFDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAGFFGALIAGLIGGIVVHYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KKIPVHKVLRSVMPIFVIPIVGTFITAGIMMWGLGEPIGALTSSLTQWLQGMQQGSIVLL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHH
AVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAIAAVSICVPPLGLGLATLIGRKN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
FSVEEREAGKAALVMGCVGVTEGAIPFAAADPLRVIPSIMVGSACGAVMAALFGAQCYAG
CCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WGGLIVLPVVEGKLGYVAAVAVGAVVTAVCVNVLKSLTRKNVSQVDEKEDDLDLDFEMN
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]