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The map label for this gene is frwB [H]

Identifier: 16767378

GI number: 16767378

Start: 4328395

End: 4328715

Strand: Direct

Name: frwB [H]

Synonym: STM4113

Alternate gene names: 16767378

Gene position: 4328395-4328715 (Clockwise)

Preceding gene: 16767377

Following gene: 16767379

Centisome position: 89.11

GC content: 50.16

Gene sequence:

>321_bases
ATGACTAAAATTATTGCAGTAACCGCGTGTCCTTCTGGTGTTGCGCATACCTATATGGCGGCTGAAGCGCTGGAAAGCGC
AGCCAAAGCGAAAGGTTGGGATGTAAAAGTGGAGACTCAGGGCTCGATTGGGCTGGAAAATGAACTGACGGCAGAGGATG
TGGCGAGCGCCGATATGGTGATTTTGACTAAAGATATCGGCATCAAGTTCGAAGAGCGGTTTGCGGGTAAAACTATCGTT
CGCGTCAATATCAGCGACGCGGTAAAACGCGCCGACGCCATTATGAACAAGATTGACGCCCATCTTTCGCAAACCGCGTA
A

Upstream 100 bases:

>100_bases
ACGTGCTGAAAAGCCTGACGCGTAAGAATGTGTCGCAAGTTGACGAAAAAGAAGACGACCTGGATTTAGATTTTGAGATG
AATTAAGCGAGGAATAAGCC

Downstream 100 bases:

>100_bases
CGTTAAAATGCCCGATGGCGCAAGTTTATCGGGCCTGCTCACAGGCCCGATAAGAGATTTATGCCGCCATCCGGCGCTCG
TGTCCACAGGAGCTCCTCAT

Product: PTS system fructose-like transporter subunit EIIB

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 2 [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWDVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIV
RVNISDAVKRADAIMNKIDAHLSQTA

Sequences:

>Translated_106_residues
MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWDVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIV
RVNISDAVKRADAIMNKIDAHLSQTA
>Mature_105_residues
TKIIAVTACPSGVAHTYMAAEALESAAKAKGWDVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIVR
VNISDAVKRADAIMNKIDAHLSQTA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=106, Percent_Identity=96.2264150943396, Blast_Score=206, Evalue=2e-55,
Organism=Escherichia coli, GI1788492, Length=88, Percent_Identity=53.4090909090909, Blast_Score=100, Evalue=3e-23,
Organism=Escherichia coli, GI87082348, Length=98, Percent_Identity=48.9795918367347, Blast_Score=99, Evalue=7e-23,
Organism=Escherichia coli, GI1788730, Length=97, Percent_Identity=44.3298969072165, Blast_Score=94, Evalue=2e-21,
Organism=Escherichia coli, GI1790390, Length=103, Percent_Identity=42.7184466019417, Blast_Score=87, Evalue=3e-19,
Organism=Escherichia coli, GI1786951, Length=94, Percent_Identity=43.6170212765958, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 11263; Mature: 11132

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWDVKVETQGSIGLENELTAEDVASADMV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCEE
ILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMNKIDAHLSQTA
EEEECCCCEEHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKIIAVTACPSGVAHTYMAAEALESAAKAKGWDVKVETQGSIGLENELTAEDVASADMV
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCEE
ILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMNKIDAHLSQTA
EEEECCCCEEHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]