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The map label for this gene is yihQ [H]

Identifier: 16767284

GI number: 16767284

Start: 4228665

End: 4230701

Strand: Reverse

Name: yihQ [H]

Synonym: STM4019

Alternate gene names: 16767284

Gene position: 4230701-4228665 (Counterclockwise)

Preceding gene: 39546384

Following gene: 16767283

Centisome position: 87.1

GC content: 55.42

Gene sequence:

>2037_bases
ATGAATTCTCTACCACAACGGTCAACCGATTTTGAACTGACAACATCACAGGATGGTTTTGCGCTTAGCTGGCAACAGCG
CCTGATTTTACGCCACAGCACCGAAAATCCCTGTCTGTGGATTGGCGCGGGCGTTGCCGACATTGACATGTTTCGCGGCA
ACTTTAGCATCAAAGACAAACTTAACGAAAAGATTGCATTAACGGAGGCCACCGTCAGCGAGCTACCTGACGGCTGGCTG
GTACAATTCAGCCGTGGCGCAACAATTAGCGCCACCCTTCGCATCTCCGCCGATGAAGCGGGACGCCTGCAGCTGGATCT
GCAAAACGACGACCTGCACCATAACCGTATCTGGTTACGTCTCGCAGCTAATCCAGACGACCATATCTACGGCTGCGGCG
AACAGTTCTCTTATTTCGATTTGCGCGGCAAGCCGTTCCCGCTGTGGACCAGCGAACAGGGCGTTGGCCGTAATAAAACC
AGCTATGTCACCTGGCAGGCAGACTGTAAAGAGAACGCCGGCGGCGACTATTACTGGACCTTCTTCCCGCAACCGACCTT
TGTCAGCACGCAGAAGTATTACTGCCACGTCGATAATAGCTGCTATATGAATTTCGACTTCAGCGCGCCGGAGTATCACG
AACTGGCGCTGTGGGAAGATAAAACTACGCTACGTTTTGAGTGTGCCGACACCTACATCGCCCTGCTGGAAAAACTGACT
GCGCTGTTAGGTCGCCAGCCGGAGCTGCCGGACTGGGTTTACGACGGCGTCACGCTAGGCATTCAGGGCGGTACGGAAGT
TTGCCAGCAAAAACTGGATACCATGCGCAACGCAGGCGTAAAAGTGAACGGTATTTGGGCGCAGGACTGGTCCGGTATCC
GCATGACCTCCTTTGGCAAGCGCGTGATGTGGAACTGGAAGTGGAATAGCGACAACTATCCACAGCTGGATAGCCGTATC
AAACAGTGGAAAGAAGAAGGCGTCCAGTTCCTCTCTTATATCAACCCATACGTCGCCAGTGATAAAGACCTCTGCGCCGA
GGCGGCGAAACACGGCTATCTGGCGAAAGACGCCACGGGCGGCGACTATCTGGTCGAGTTTGGCGAATTCTATGGCGGCG
TGGTCGATCTGACCAATCCTGAAGCTTACGACTGGTTCAAAGACGTCATCAAAAAGAGCATGATCGCGCTCGGCTGCAGC
GGCTGGATGGCGGATTTCGGCGAATATCTGCCGACCGACACGTATCTGCACAACGGCGTCAGCGCCGAGATCATGCATAA
CGCCTGGCCTGCGCTCTGGGCGAAATGTAACTACGAAGCGCTACAGGAGACCGGCAAGCTCGGCGAGATCCTGTTCTTTA
TGCGTGCGGGTTACACCGGCAGTCAGAAATATTCCACCATGATGTGGGCAGGTGACCAGAACGTTGACTGGAGCCTTGAT
GATGGTCTGGCCTCTGTCGTGCCTGCGGCATTGTCGCTGGCAATGACCGGCCATGGTCTGCATCACAGCGATATCGGCGG
CTACACCACCCTGTTTGACATGAAACGCAGCAAAGAGTTGCTGCTGCGCTGGTGCGATTTCAGCGCCTTTACGCCGATGA
TGCGCACCCATGAAGGCAACCGCCCCGGCGATAACTGGCAGTTCGACGGCGACGCGGAAACTATTGCCCACTTTGCCCGC
ATGACCACCGTCTTTACCACGCTGAAACCGTATCTCAAGCAGGCGGTGGCGCAAAACGCGGCTACCGGTCTGCCGGTCAT
GCGTCCGCTATTCCTGCATTACGAGAACGATGCCGCAACCTACACCCTGAAATATCAATATCTGCTCGGTCAGGATCTGC
TGGTCGCGCCGGTTCACGAGCAGGGGCGTTGCGACTGGACGCTGTACCTGCCGGAAGATCACTGGGTGAATATCTGGACC
GGCGAAGCTCACCACGGCGGTGAAATTACCGTGGATGCGCCCATTGGCAAGCCGCCGGTCTTCTATCGCGCGAAGAGCGA
GTGGGCTTCACTTTTTGCTTCTTTACGGAATATCTAA

Upstream 100 bases:

>100_bases
ATTCATCTTGCCCCAAAAGCGATCCATCAACTGCATTTTTCCATCGGCTGCGACTAGCCCAAATGGATTACCGAATTACC
CTACATTCACGGAGATTACA

Downstream 100 bases:

>100_bases
TACGGCTCGCCCGCAGGGAAACCTGCGGGCAGATGGAGAAGAATAATGAGTCAAACATCATCGAATCCGGCAACCCTACG
CTTGCCGTTTAAAGAAAAAC

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSTENPCLWIGAGVADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWL
VQFSRGATISATLRISADEAGRLQLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRI
KQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKSMIALGCS
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYTLKYQYLLGQDLLVAPVHEQGRCDWTLYLPEDHWVNIWT
GEAHHGGEITVDAPIGKPPVFYRAKSEWASLFASLRNI

Sequences:

>Translated_678_residues
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSTENPCLWIGAGVADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWL
VQFSRGATISATLRISADEAGRLQLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRI
KQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKSMIALGCS
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYTLKYQYLLGQDLLVAPVHEQGRCDWTLYLPEDHWVNIWT
GEAHHGGEITVDAPIGKPPVFYRAKSEWASLFASLRNI
>Mature_678_residues
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSTENPCLWIGAGVADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWL
VQFSRGATISATLRISADEAGRLQLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRI
KQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKSMIALGCS
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYTLKYQYLLGQDLLVAPVHEQGRCDWTLYLPEDHWVNIWT
GEAHHGGEITVDAPIGKPPVFYRAKSEWASLFASLRNI

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=340, Percent_Identity=25.5882352941176, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI88900491, Length=387, Percent_Identity=25.5813953488372, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI38202257, Length=387, Percent_Identity=25.5813953488372, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI66346737, Length=397, Percent_Identity=26.1964735516373, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI119393895, Length=450, Percent_Identity=22.6666666666667, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI119393893, Length=450, Percent_Identity=22.6666666666667, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI119393891, Length=450, Percent_Identity=22.6666666666667, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI310115361, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI221316699, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI2367323, Length=678, Percent_Identity=87.7581120943953, Blast_Score=1267, Evalue=0.0,
Organism=Escherichia coli, GI2367256, Length=549, Percent_Identity=23.6794171220401, Blast_Score=171, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17560800, Length=380, Percent_Identity=23.6842105263158, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17560798, Length=380, Percent_Identity=23.6842105263158, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71991189, Length=342, Percent_Identity=25.4385964912281, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32563849, Length=231, Percent_Identity=30.7359307359307, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71985706, Length=237, Percent_Identity=30.379746835443, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319706, Length=389, Percent_Identity=22.107969151671, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24650054, Length=364, Percent_Identity=23.6263736263736, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643749, Length=400, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24643753, Length=400, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24643751, Length=400, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24643746, Length=400, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21357605, Length=400, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 76999; Mature: 76999

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSTENPCLWIGAGVADIDMFRGNFSIKDK
CCCCCCCCCCEEEEECCCCEEEEHHHEEEEEECCCCCEEEEECCCEEEEEECCCCEEHHH
LNEKIALTEATVSELPDGWLVQFSRGATISATLRISADEAGRLQLDLQNDDLHHNRIWLR
CCCEEEEEHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEEEE
LAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKTSYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ECCCCCEEECCEEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSDNYPQLDSRIKQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKSMIALGCSGWMADFGEYLPTDTYLHNGV
CHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAAT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEEECCCEE
YTLKYQYLLGQDLLVAPVHEQGRCDWTLYLPEDHWVNIWTGEAHHGGEITVDAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCE
FYRAKSEWASLFASLRNI
EEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSTENPCLWIGAGVADIDMFRGNFSIKDK
CCCCCCCCCCEEEEECCCCEEEEHHHEEEEEECCCCCEEEEECCCEEEEEECCCCEEHHH
LNEKIALTEATVSELPDGWLVQFSRGATISATLRISADEAGRLQLDLQNDDLHHNRIWLR
CCCEEEEEHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEEEE
LAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKTSYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ECCCCCEEECCEEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSDNYPQLDSRIKQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKSMIALGCSGWMADFGEYLPTDTYLHNGV
CHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAAT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEEECCCEE
YTLKYQYLLGQDLLVAPVHEQGRCDWTLYLPEDHWVNIWTGEAHHGGEITVDAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCE
FYRAKSEWASLFASLRNI
EEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]