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The map label for this gene is yihO

Identifier: 16767282

GI number: 16767282

Start: 4225770

End: 4227191

Strand: Reverse

Name: yihO

Synonym: STM4017

Alternate gene names: 16767282

Gene position: 4227191-4225770 (Counterclockwise)

Preceding gene: 16767283

Following gene: 16767281

Centisome position: 87.03

GC content: 47.05

Gene sequence:

>1422_bases
ATGTCTAATCATGATCCGCTAACGCTAAAGTTGAGCCTGCGGGAAAAATGCGCCTATGGCGTGGGCGATTTCGGCTCAAA
TCTGATGCTGTGTATCGGTACGCTGTATCTACTGAAGTTTTATACCGATGAACTCGGGATGCCTGCATATTACGGTGGAA
TTATCTTTCTGGTGGCGAAATTCTTCACCGCTTTTACCGATATGCTCACCGGCGTATTGCTGGACTCACGCCGTAATATT
GGCGCAAAAGGAAAGTTTCGGCCTTTTATTCTGTATGCGTCATTTCCAGTCGCTCTGGTTGCTACTGCGCAATTCTTTGC
CACTCACTTTACTTTACCCGTTAAAACAGCCTTCGCGACGGTGCTGTTTATGTTGTTCGGTCTGTTCTACAGCCTGATGA
ACTGCTCATACGGCGCGATGGTACCCGCTATTACCAAAAATCCGCATGAGCGCGCCCAGCTCGCCGCATGGCGACAAGGC
GGCGCTACCATTGGCCTTCTTCTTTGTACCGTAGGTTTTATGCCCATTCAGGCGCTGTTTACCCGTTCCCCTTCGCTGGG
TTATCTGATTGCAGCAGTCATCTTTTCGGTCTGCGGGCTGTTCAGCATGTGGTGGTGCTTTAGCGGGGTAAAAGAACGGT
ATATCGAAACCGTACCTGACACGCATAAACCCAGCATATTGAAGTCCTTCTGCGCGATTTTTCGTAATCCGCCGCTGCTG
GTGCTCTGCGTTGCCAATTTGTGCACGCTGGCCGCCTTTAATATCAAGCTGGCCATTCAGGTTTATTACACTCAGTACGT
GCTGAACGATATTCATTTGTTGTCATGGATGGGTTTTTTCAGCATGGGCTGTATCCTGATTGGTGTTTTATTAGTACCTG
CTGCGGTAAAACGCTTCGGGAAAAAACAGGTTTATCTTGGTGGTCTGATATTGTGGGCCGTTGGCGATATCCTGAATTTT
ATCTGGGGTGGAACGTCATTCCTGTTTGTTATTTTCTCTTGTATCGCCTTCTTCGGTACCGCTTTCGTCAACAGCCTGAA
CTGGGCGCTGGTTCCGGATACGGTTGACTACGGTGAATGGAAAACGGGTATTCGCGCTGAAGGCTCGGTGTATACGGGTT
ATACCTTTTCCCGCAAAATTTCCGCTGCGCTTGCTGGCTTTTTGCCAGGTATTATGCTGACGCAAATCGGTTATATCCCC
AACATAGCTCAAAGTGACACCACGTTGCTTGGTTTGCGTCAGCTCATTTTTTTATGGCCTTGCGGTCTTGCCATTATCGC
AGCACTAACGATGGGCTTTTTTTATAAGCTCAATGAACAACGTTTCGCTTTTATTATCGAGGAAATTGCCCAACGAAAGA
AAACAGGTAATCAAATTGTCGCGACTAATAATAAACAAAGTATTTCTACTGTAAATAATTAA

Upstream 100 bases:

>100_bases
GAAGATGTACGTGCGAATTGTGGAAGAGATTGAGGCCCGGAAACATACGGTTTAACAACAATAAAATATAACGCCCTGCG
GGGCGTTTTGAGAGGCGATT

Downstream 100 bases:

>100_bases
ACGACGCTTGCCGCTTTATCCATCCCGATGGATGGCGGCTTCCCTATATTTGAAAAATGGATTTATTATGAAATCTCTGA
ATACTCTAGTGATATTAACT

Product: GPH family transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDELGMPAYYGGIIFLVAKFFTAFTDMLTGVLLDSRRNI
GAKGKFRPFILYASFPVALVATAQFFATHFTLPVKTAFATVLFMLFGLFYSLMNCSYGAMVPAITKNPHERAQLAAWRQG
GATIGLLLCTVGFMPIQALFTRSPSLGYLIAAVIFSVCGLFSMWWCFSGVKERYIETVPDTHKPSILKSFCAIFRNPPLL
VLCVANLCTLAAFNIKLAIQVYYTQYVLNDIHLLSWMGFFSMGCILIGVLLVPAAVKRFGKKQVYLGGLILWAVGDILNF
IWGGTSFLFVIFSCIAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFSRKISAALAGFLPGIMLTQIGYIP
NIAQSDTTLLGLRQLIFLWPCGLAIIAALTMGFFYKLNEQRFAFIIEEIAQRKKTGNQIVATNNKQSISTVNN

Sequences:

>Translated_473_residues
MSNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDELGMPAYYGGIIFLVAKFFTAFTDMLTGVLLDSRRNI
GAKGKFRPFILYASFPVALVATAQFFATHFTLPVKTAFATVLFMLFGLFYSLMNCSYGAMVPAITKNPHERAQLAAWRQG
GATIGLLLCTVGFMPIQALFTRSPSLGYLIAAVIFSVCGLFSMWWCFSGVKERYIETVPDTHKPSILKSFCAIFRNPPLL
VLCVANLCTLAAFNIKLAIQVYYTQYVLNDIHLLSWMGFFSMGCILIGVLLVPAAVKRFGKKQVYLGGLILWAVGDILNF
IWGGTSFLFVIFSCIAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFSRKISAALAGFLPGIMLTQIGYIP
NIAQSDTTLLGLRQLIFLWPCGLAIIAALTMGFFYKLNEQRFAFIIEEIAQRKKTGNQIVATNNKQSISTVNN
>Mature_472_residues
SNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDELGMPAYYGGIIFLVAKFFTAFTDMLTGVLLDSRRNIG
AKGKFRPFILYASFPVALVATAQFFATHFTLPVKTAFATVLFMLFGLFYSLMNCSYGAMVPAITKNPHERAQLAAWRQGG
ATIGLLLCTVGFMPIQALFTRSPSLGYLIAAVIFSVCGLFSMWWCFSGVKERYIETVPDTHKPSILKSFCAIFRNPPLLV
LCVANLCTLAAFNIKLAIQVYYTQYVLNDIHLLSWMGFFSMGCILIGVLLVPAAVKRFGKKQVYLGGLILWAVGDILNFI
WGGTSFLFVIFSCIAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFSRKISAALAGFLPGIMLTQIGYIPN
IAQSDTTLLGLRQLIFLWPCGLAIIAALTMGFFYKLNEQRFAFIIEEIAQRKKTGNQIVATNNKQSISTVNN

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family

Homologues:

Organism=Homo sapiens, GI122937339, Length=443, Percent_Identity=23.4762979683973, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI48994989, Length=471, Percent_Identity=80.2547770700637, Blast_Score=771, Evalue=0.0,
Organism=Escherichia coli, GI145693206, Length=457, Percent_Identity=67.1772428884026, Blast_Score=646, Evalue=0.0,
Organism=Escherichia coli, GI1787902, Length=463, Percent_Identity=32.829373650108, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI87082306, Length=462, Percent_Identity=28.3549783549784, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786466, Length=460, Percent_Identity=26.0869565217391, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790561, Length=445, Percent_Identity=27.1910112359551, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YIHO_SALTY (Q9L7R4)

Other databases:

- EMBL:   AF220438
- EMBL:   AE006468
- RefSeq:   NP_462897.1
- ProteinModelPortal:   Q9L7R4
- GeneID:   1255543
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM4017
- HOGENOM:   HBG518114
- OMA:   VIFLIAK
- ProtClustDB:   CLSK880801
- BioCyc:   STYP99287:STM4017-MONOMER
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043
- TIGRFAMs:   TIGR00792

Pfam domain/function: SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 52362; Mature: 52230

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00872 NA_GALACTOSIDE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x123e8aa4)-; HASH(0x13133244)-; HASH(0x12b5cfc8)-; HASH(0x1251eaf4)-; HASH(0x1263eff0)-; HASH(0x12e02be4)-; HASH(0x13000e3c)-; HASH(0x12e69c24)-; HASH(0x12d86958)-; HASH(0x12d418b0)-; HASH(0x130c11f4)-;

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCH
>Mature Secondary Structure 
SNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDELGMPAYYGGIIFLVAK
CCCCCEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH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HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609