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The map label for this gene is rtcA [H]

Identifier: 16766806

GI number: 16766806

Start: 3680340

End: 3681359

Strand: Reverse

Name: rtcA [H]

Synonym: STM3518

Alternate gene names: 16766806

Gene position: 3681359-3680340 (Counterclockwise)

Preceding gene: 16766807

Following gene: 16766805

Centisome position: 75.79

GC content: 62.94

Gene sequence:

>1020_bases
ATGGCAAGGATCATCGCGCTGGATGGCGCACAGGGAGAGGGCGGCGGGCAGATTTTGCGCTCGGCGCTGAGTTTATCAAT
GATAACCGGCCAGCCGTTTGAAATGAGCGGCATCCGCGCCGGGCGCGCTAAACCGGGGCTGCTACGCCAGCATTTAACGG
CGGTGCGAGCGGCAACGGAAATCTGCGGCGCGCAGGTGAACGGCGACGAGCTGGGCTCGCAACAGTTGCGTTTTACGCCG
GGGCCGATTCGCGGCGGCGAGTACCGTTTTGCGATTGGCAGCGCGGGCAGTTGTATGCTGGTGCTGCAAACCGTCCTGCC
CGCGCTGTGGTTTGCTGACGGTTCATCCCGCGTGGAGGTTCACGGCGGGACGCATAATCAGGCCGCGCCCAGCGCTGATT
TTATCTGCCGCGTCTGGGAACCGCTGTTGGCGAGGATGGGCATCAGCCAGCGCACCACGCTGATAAAACACGGCTTTTAT
CCGGCAGGCGGCGGCGCGGCGGCAACGGTCGTCGAACCGGCAGCGTCTTTACGCGGTCTGACGCTGATATCGCGCGGCGA
GACGCTGCGCACCACCGCTGAAGCTTTGCTGGCGGCGGTTCCTTACCACGTTGGCGAACGTGAAGTCGCAACGCTGGAAG
CCCACTTCCCGCAGGCGGAGAAAAACGTCGTTGCGCTGGAAGGCGGCTGCGGGCCGGGCAACGCGCTGTCGCTGATGATT
CAAAGCGAACAACTGACCGAACTGTTCGCCGCGTTCGGCGTAAAAGGCACCAGCGCGGAAGCGGTAGCTAACCAGGTTGC
GCATGAAGCGCGGCGCTATCTCGCAAGCCCGGCGGCGGTGGGAGAGCATCTGGCCGACCAGCTGATTTTACCGCTGGCGC
TGGCGGGCGAGGGCGCGTTTACCGTGGCACGGGCCTCCGCTCACTTGCTTACCAATATTGCGGTGGTGGAACGGTTTTTG
CCGGTCAGATTTTCCTGTGAAGCAACCGAAAGTGGCTATCTTGTCCGGGTAAGCGACTAA

Upstream 100 bases:

>100_bases
AATGGCGTATAAAGATATTGATGCGGTGATGGCGGCGCAGTCCGACCTGGTTGAAATCATGTACGCCCTGCGGCAGGTGG
TGTGCGTTAAAGGATAGAAA

Downstream 100 bases:

>100_bases
GTCATCTTTACGAGCATTGCAAGGCAAACATCCGGGCCCGGTTTGTATGTGTGTCTCAGTTGAGCTACAATTTGAACTGT
ATAGAGACACAGTACAGGAG

Product: RNA 3'-terminal-phosphate cyclase

Products: NA

Alternate protein names: RNA cyclase; RNA-3'-phosphate cyclase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATEICGAQVNGDELGSQQLRFTP
GPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEVHGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFY
PAGGGAAATVVEPAASLRGLTLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMI
QSEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAFTVARASAHLLTNIAVVERFL
PVRFSCEATESGYLVRVSD

Sequences:

>Translated_339_residues
MARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATEICGAQVNGDELGSQQLRFTP
GPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEVHGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFY
PAGGGAAATVVEPAASLRGLTLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMI
QSEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAFTVARASAHLLTNIAVVERFL
PVRFSCEATESGYLVRVSD
>Mature_338_residues
ARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATEICGAQVNGDELGSQQLRFTPG
PIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEVHGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFYP
AGGGAAATVVEPAASLRGLTLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMIQ
SEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAFTVARASAHLLTNIAVVERFLP
VRFSCEATESGYLVRVSD

Specific function: Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps:(A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A;

COG id: COG0430

COG function: function code A; RNA 3'-terminal phosphate cyclase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4506589, Length=344, Percent_Identity=31.1046511627907, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI195927044, Length=357, Percent_Identity=29.9719887955182, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI48994937, Length=338, Percent_Identity=68.3431952662722, Blast_Score=443, Evalue=1e-126,
Organism=Drosophila melanogaster, GI18543269, Length=344, Percent_Identity=29.3604651162791, Blast_Score=144, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013791
- InterPro:   IPR000228
- InterPro:   IPR013796
- InterPro:   IPR020723
- InterPro:   IPR017770
- InterPro:   IPR013792 [H]

Pfam domain/function: PF01137 RTC; PF05189 RTC_insert [H]

EC number: =6.5.1.4 [H]

Molecular weight: Translated: 35458; Mature: 35327

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATE
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ICGAQVNGDELGSQQLRFTPGPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEV
HHCCCCCHHHCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCEEEE
HGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFYPAGGGAAATVVEPAASLRGL
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHCCHHHHHCCE
TLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMI
EEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEE
QSEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAF
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCE
TVARASAHLLTNIAVVERFLPVRFSCEATESGYLVRVSD
EEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECC
>Mature Secondary Structure 
ARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATE
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ICGAQVNGDELGSQQLRFTPGPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEV
HHCCCCCHHHCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCEEEE
HGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFYPAGGGAAATVVEPAASLRGL
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHCCHHHHHCCE
TLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMI
EEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEE
QSEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAF
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCE
TVARASAHLLTNIAVVERFLPVRFSCEATESGYLVRVSD
EEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA