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The map label for this gene is acrE [H]

Identifier: 16766685

GI number: 16766685

Start: 3561104

End: 3562261

Strand: Direct

Name: acrE [H]

Synonym: STM3390

Alternate gene names: 16766685

Gene position: 3561104-3562261 (Clockwise)

Preceding gene: 16766683

Following gene: 16766686

Centisome position: 73.31

GC content: 55.18

Gene sequence:

>1158_bases
ATGACGAAACATGCCAGGTTTTCACTCCTGCCCTCATTCATCATATTCTCTGCTGCGCTGCTGGCCGGTTGTAATGACCA
GGGAGATACCCAGGCTCATGCCGGCGAGCCGCAAGTCACCGTCCATGTGGTCGAAACAGCGCCGCTAGCCGTAACGACCG
AACTTCCCGGACGTACGTCCGCATTTCGCATTGCGGAGGTTCGCCCCCAGGTGAGCGGGATCGTGCTTAAAAGAAACTTC
ACCGAAGGTAGCGATGTAGAGGCCGGGCAGTCGCTCTATCAGATCGATCCTGCCACTTATCAGGCTGATTATGACAGCGC
TAAAGGCGAACTTGCTAAAAGCGAAGCGGCTGCGGCTATCGCGCACCTGACGGTCAAACGCTATGTTCCACTGGTCGGCA
CAAAATATATCAGCCAACAGGAATATGATCAGGCGATTGCCGACGCCCGCCAGGCCGATGCCGCCGTTGTGGCGGCAAAA
GCCGCTGTTGAAAGCGCGCGTATTAACCTTGCGTATACCAAAGTCACCTCACCCATCAGCGGGCGTATAGGAAAATCTAA
TGTGACTGAAGGCGCGCTGGTGACTAATGGTCAGTCAACTGAACTGGCTACCGTGCAACAACTCGATCCGATTTATGTCG
ACGTGACGCAATCAAGCAACGACTTTATGCGACTCAAGCAATCCGTCGAACAAGGTAACCTGCATAAAGACAGCGCCAGT
AGCACGGTTCAACTGGTAATGGAAAATGGTCAGGTCTACCCGATTAAAGGCACGCTGCAATTTTCCGACGTTACCGTAGA
TGAAAGCACCGGCTCTATCACGCTCAGGGCGGTGTTCCCTAACCCGCAACACAGTCTGCTTCCCGGTATGTTTGTTCGCG
CCCGCATTGATGAAGGCGTCCAGCCCAATGCCATCCTTGTCCCCCAGCAGGGCGTAACCCGCACGCCGCGCGGCGACGCA
ATGGTGATGGTGGTTAACGATAAAAGCCAGGTCGAAGCCCGCAATGTCGTGGCGGCGCAGGCTATTGGCGATAAATGGCT
CATCAGCGAAGGGTTAAAACCGGGCGATAAGGTCATCGTCAGCGGCTTACAAAAAGCGCGACCGGGCGTCCAGGTGAAAG
CCACTACCGATGCTCCTGCAGCGAAAACGGCGCAATAA

Upstream 100 bases:

>100_bases
AATAATTTGTAGGATACCCCACTGCTATTCTATTTTTCGCGCGTTAACGCCTTACCGTTATCCGGTGAATAACGAGCTTT
CGGTTTTTTAAGGAACAGTA

Downstream 100 bases:

>100_bases
GGTAACCGTACATGGCAAACTTTTTTATTAGACGTCCTATTTTCGCCTGGGTTCTGGCCATTATCCTGATGATGGCTGGC
GCACTGGCAATAATGCAACT

Product: acriflavine resistance protein E precursor

Products: NA

Alternate protein names: Protein envC [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTKHARFSLLPSFIIFSAALLAGCNDQGDTQAHAGEPQVTVHVVETAPLAVTTELPGRTSAFRIAEVRPQVSGIVLKRNF
TEGSDVEAGQSLYQIDPATYQADYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVVAAK
AAVESARINLAYTKVTSPISGRIGKSNVTEGALVTNGQSTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKDSAS
STVQLVMENGQVYPIKGTLQFSDVTVDESTGSITLRAVFPNPQHSLLPGMFVRARIDEGVQPNAILVPQQGVTRTPRGDA
MVMVVNDKSQVEARNVVAAQAIGDKWLISEGLKPGDKVIVSGLQKARPGVQVKATTDAPAAKTAQ

Sequences:

>Translated_385_residues
MTKHARFSLLPSFIIFSAALLAGCNDQGDTQAHAGEPQVTVHVVETAPLAVTTELPGRTSAFRIAEVRPQVSGIVLKRNF
TEGSDVEAGQSLYQIDPATYQADYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVVAAK
AAVESARINLAYTKVTSPISGRIGKSNVTEGALVTNGQSTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKDSAS
STVQLVMENGQVYPIKGTLQFSDVTVDESTGSITLRAVFPNPQHSLLPGMFVRARIDEGVQPNAILVPQQGVTRTPRGDA
MVMVVNDKSQVEARNVVAAQAIGDKWLISEGLKPGDKVIVSGLQKARPGVQVKATTDAPAAKTAQ
>Mature_384_residues
TKHARFSLLPSFIIFSAALLAGCNDQGDTQAHAGEPQVTVHVVETAPLAVTTELPGRTSAFRIAEVRPQVSGIVLKRNFT
EGSDVEAGQSLYQIDPATYQADYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVVAAKA
AVESARINLAYTKVTSPISGRIGKSNVTEGALVTNGQSTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKDSASS
TVQLVMENGQVYPIKGTLQFSDVTVDESTGSITLRAVFPNPQHSLLPGMFVRARIDEGVQPNAILVPQQGVTRTPRGDAM
VMVVNDKSQVEARNVVAAQAIGDKWLISEGLKPGDKVIVSGLQKARPGVQVKATTDAPAAKTAQ

Specific function: May affect specific membrane functions, such as septum formation during cell division, and cell membrane permeability [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=380, Percent_Identity=88.6842105263158, Blast_Score=672, Evalue=0.0,
Organism=Escherichia coli, GI1786668, Length=375, Percent_Identity=70.4, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789929, Length=373, Percent_Identity=50.402144772118, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI87082036, Length=321, Percent_Identity=29.2834890965732, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40964; Mature: 40832

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHARFSLLPSFIIFSAALLAGCNDQGDTQAHAGEPQVTVHVVETAPLAVTTELPGRTS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCC
AFRIAEVRPQVSGIVLKRNFTEGSDVEAGQSLYQIDPATYQADYDSAKGELAKSEAAAAI
EEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEECCCEEECCCCCCCCHHHHHHHHHHH
AHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVVAAKAAVESARINLAYTKVTSPIS
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEEEECCCCC
GRIGKSNVTEGALVTNGQSTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKDSAS
CCCCCCCCCCCEEEECCCCCCEEHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
STVQLVMENGQVYPIKGTLQFSDVTVDESTGSITLRAVFPNPQHSLLPGMFVRARIDEGV
CEEEEEEECCEEEEEEEEEEEEEEEEECCCCCEEEEEECCCCCCHHCCCCEEEEHHCCCC
QPNAILVPQQGVTRTPRGDAMVMVVNDKSQVEARNVVAAQAIGDKWLISEGLKPGDKVIV
CCCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHEEEEHHCCCHHHHHCCCCCCHHHHH
SGLQKARPGVQVKATTDAPAAKTAQ
HHHHHCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
TKHARFSLLPSFIIFSAALLAGCNDQGDTQAHAGEPQVTVHVVETAPLAVTTELPGRTS
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCC
AFRIAEVRPQVSGIVLKRNFTEGSDVEAGQSLYQIDPATYQADYDSAKGELAKSEAAAAI
EEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEECCCEEECCCCCCCCHHHHHHHHHHH
AHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVVAAKAAVESARINLAYTKVTSPIS
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEEEECCCCC
GRIGKSNVTEGALVTNGQSTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKDSAS
CCCCCCCCCCCEEEECCCCCCEEHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
STVQLVMENGQVYPIKGTLQFSDVTVDESTGSITLRAVFPNPQHSLLPGMFVRARIDEGV
CEEEEEEECCEEEEEEEEEEEEEEEEECCCCCEEEEEECCCCCCHHCCCCEEEEHHCCCC
QPNAILVPQQGVTRTPRGDAMVMVVNDKSQVEARNVVAAQAIGDKWLISEGLKPGDKVIV
CCCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHEEEEHHCCCHHHHHCCCCCCHHHHH
SGLQKARPGVQVKATTDAPAAKTAQ
HHHHHCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1720861; 9278503 [H]