Click here to switch to the map view.

The map label for this gene is iraD [H]

Identifier: 16766430

GI number: 16766430

Start: 3290592

End: 3290972

Strand: Reverse

Name: iraD [H]

Synonym: STM3130

Alternate gene names: 16766430

Gene position: 3290972-3290592 (Counterclockwise)

Preceding gene: 16766431

Following gene: 16766428

Centisome position: 67.75

GC content: 50.92

Gene sequence:

>381_bases
ATGATGACACCAACCATTCCGGTCGCGCTATTCGACAGGCTCTTGGTTGAGGGGATAAGCCCACATGAATTGGTACGACG
CAAGTTAATGTGTTTATTCAACTCTTGCGCCGTGCCAGGTGGCGAGACATTACCGCCGCTGCTCACTCGGGGTATGCCGG
AATGGCACGAGGTGAATGTGGGTGACAAACGGGTTCTCAACTGGTTTTGCCGTGAGCTTCGCGCTGCTATTTTACGTTAT
GAACCGAGCATCAATATGCTGAAAGTCAGTGTAAAAGATGCCCATCATCAGACGCTGGCGTTGTCTTTGGAAGCGATGTT
ACAGGATGAGTCTGAACCGTTAAGGCTGGAGATAGCCTACTCTAACGGTAGATGGCGCTAG

Upstream 100 bases:

>100_bases
CGAAAATCGAATGGCAAATCACTGCCGAGAAATCAGACGGCGCTCAGCAGGAGTCCAGAACGTCAGTATGGGATCTGGCG
ATGAACCAGATAGGGAAATG

Downstream 100 bases:

>100_bases
TAATGCAGGAAGGAACGCCGGGCCGGGCGTTTAACATTATCCCAAAAGCAAAAAAACGCAGCGAGCGAACCTGATAATCA
GGCAGACAGTCCACCTTTCG

Product: DNA replication/recombination/repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRY
EPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR

Sequences:

>Translated_126_residues
MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRY
EPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR
>Mature_126_residues
MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRY
EPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR

Specific function: Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of Rss

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GpW/Gp25 family. IraD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082422, Length=102, Percent_Identity=46.078431372549, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015801
- InterPro:   IPR007048 [H]

Pfam domain/function: PF04965 GPW_gp25 [H]

EC number: NA

Molecular weight: Translated: 14436; Mature: 14436

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNV
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCCCC
GDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAY
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEE
SNGRWR
CCCCCC
>Mature Secondary Structure
MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNV
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCCCC
GDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAY
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEE
SNGRWR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA