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The map label for this gene is fucK [H]

Identifier: 16766281

GI number: 16766281

Start: 3130096

End: 3131514

Strand: Direct

Name: fucK [H]

Synonym: STM2977

Alternate gene names: 16766281

Gene position: 3130096-3131514 (Clockwise)

Preceding gene: 16766280

Following gene: 16766282

Centisome position: 64.44

GC content: 58.7

Gene sequence:

>1419_bases
ATGAAACAAGACGTTATCCTGGTTCTCGACTGCGGTGCGACAAACGTTCGGGCGATCGCCGTTGATCGCCAGGGGAAAAT
TGTCGCCCGCGCCTCAACCGCTAACGCCAGCGACATTGCCGCAGAAAATAGCGCCTGGCATCAGTGGTCGCTGGACGCCA
TCCTGCAACGTTTCGCCGATTGTTGCAGGTCACTCTCCAGCGCCCTGTCGGAGTGTGTTGTTCGCGGTATTACGGTGACT
ACGTTCGGCGTCGATGGCGCGCTGGTCGATGCGCAGGGCAAGCTGCTCTACCCGGTCATCAGTTGGAAATGCCCGCGAAC
CGCTGCCGTGATGGAAACGATTGAGCGCTTTATCTCGCCCCGGCAATTGCAGACGCTCTCCGGCGTCGGCGCGTTCAGCT
TTAACACGCTGTATAAACTGGTCTGGCTTAAAGAGAATCATCCGCGCCTGCTGGAACAAGCTCACTGCTGGCTGTTTATC
TCGTCGCTGATTAACCACCGTCTGACCGGCGAGTTTACGACCGATATCACTATGGCAGGCACCAGCCAGCTCCTGGATAT
CCATCAGCGCGACTTTAGTCCGGAAATCCTGCAGGCGACGGGCCTGGCGCGCCGCCTGTTCCCGCGTATCGTGGAAGCGG
GCGCCCCGATAGGCACGCTACAGACAGACGCGGCCAGGCTACTCGGTCTCCCGGCGGGTGTGCCGGTGATCTCTGCCGGA
CACGATACTCAGTTCGCGTTATTCGGCGCTGGCGCGCAGCAAGGTGAACCGGTGCTCTCCTCCGGAACATGGGAGATTCT
GATGGTGCGCAGCGGTCAAGTGGATACCTCGCTGCTCAGTCAGTATCCGGGCTCGACCTGTGAACTGGACAGTCAGTCGG
GGCTTTATAACCCCGGAATGCAGTGGCTGGCCTCCGGTGTACTCGAATGGGTACGAAAACTGCTGTGGACGCCGGAAACG
CCATGGCAAACGCTGATCGACGAAGCGCGCGCTATTCCCGCTGGCGCGGAAGGCGTACGGATGCAGTGCGATCTGCTCGC
CTGCCAAAATGCAGGCTGGCAGGGCGTGACGCTCAATACCACCCGCGGCCATTTCTATCGCGCCGCGCTGGAAGGCCTGA
CGGCGCAACTTCAGCGTAATCTGCGCACGCTGGAGAAAATCGGCCATTTTAACGCCACAGAACTGTTACTGGTTGGCGGC
GGCAGTCGCAACGCTTTATGGAATCAAATTAAAGCGAATCAGCTTGATATCCCTATCAAAGTGCTGGACGACGCGGAAAC
CACCGTGGCCGGCGCTGCCATGTTTGGCTGGTACGGCGTAGGCGAATTTAGTAGCCCGGAACAGGCGCGCGCGCAGGTCA
ATTATCAGTATCGTTATTTCTGGCCGCAAACCGAACCTGAAATTATTGAGGGAGTATGA

Upstream 100 bases:

>100_bases
TGCGGCTTAGGCCGGTGGCGCAGGTTTACCGGGACTACGGGCGCGTGAACCGTAGGCCGGATAAGCGTAGCGCCATCGGG
CGGCGTTTATGGAGTTATCT

Downstream 100 bases:

>100_bases
AATGCTAAAAACCATTTCACCGTTAATTTCCCCGACACTGCTCAAAGTGCTGGCCGAGATGGGCCACGGGGACGAAATCA
TTTTTTCCGACGCTCACTTT

Product: L-fuculokinase

Products: NA

Alternate protein names: L-fuculose kinase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAG
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGG
GSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV

Sequences:

>Translated_472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAG
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGG
GSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
>Mature_472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAG
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGG
GSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV

Specific function: Fucose metabolism; second step. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789168, Length=472, Percent_Identity=84.7457627118644, Blast_Score=845, Evalue=0.0,
Organism=Escherichia coli, GI1787789, Length=469, Percent_Identity=23.6673773987207, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789987, Length=424, Percent_Identity=26.1792452830189, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790338, Length=420, Percent_Identity=24.5238095238095, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790005, Length=489, Percent_Identity=23.5173824130879, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789138, Length=318, Percent_Identity=24.8427672955975, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR013450 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.51 [H]

Molecular weight: Translated: 51674; Mature: 51674

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFAD
CCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHH
CCRSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISP
HHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
RQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAG
HHHHHHHCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
TSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECC
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGM
CCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEECCCCCCCCCCHH
QWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEC
TRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGGGSRNALWNQIKANQLDIPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEE
VLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
EECCCCHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCCHHHCCC
>Mature Secondary Structure
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFAD
CCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHH
CCRSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISP
HHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
RQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAG
HHHHHHHCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
TSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECC
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGM
CCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEECCCCCCCCCCHH
QWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEC
TRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGGGSRNALWNQIKANQLDIPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEE
VLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
EECCCCHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]