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The map label for this gene is prgH

Identifier: 16766180

GI number: 16766180

Start: 3016342

End: 3017520

Strand: Reverse

Name: prgH

Synonym: STM2874

Alternate gene names: 16766180

Gene position: 3017520-3016342 (Counterclockwise)

Preceding gene: 16766184

Following gene: 16766179

Centisome position: 62.12

GC content: 48.94

Gene sequence:

>1179_bases
ATGGAAACATCAAAAGAGAAGACGATAACAAGCCCAGGGCCATACATAGTTCGATTACTTAACAGCTCACTGAACGGCTG
TGAGTTTCCATTGCTGACAGGCCGAACACTCTTTGTGGTAGGTCAGAGTGATGCGCTCACTGCTTCAGGTCAACTCCCTG
ATATACCTGCCGATAGCTTTTTTATCCCGCTGGACCATGGCGGAGTAAATTTTGAAATCCAGGTGGATACGGATGCGACC
GAAATTATACTCCATGAGCTGAAAGAAGGAAATTCTGAATCTCGTTCGGTGCAATTAAATACGCCAATACAGGTCGGTGA
ATTGCTTATCCTGATTCGCCCGGAAAGCGAGCCGTGGGTGCCCGAGCAGCCTGAGAAGTTAGAAACGTCTGCAAAAAAGA
ACGAGCCGCGTTTTAAAAACGGAATTGTAGCAGCACTGGCCGGGTTTTTTATATTGGGAATTGGGACTGTGGGGACGTTA
TGGATACTTAACTCGCCGCAGCGGCAGGCCGCAGAGCTCGATTCGTTATTGGGGCAGGAGAAGGAGCGTTTTCAGGTGTT
GCCAGGCCGGGACAAAATGCTCTATGTCGCTGCGCAAAATGAAAGAGATACGTTGTGGGCTCGTCAGGTTTTAGCGAGGG
GCGATTATGATAAAAATGCGCGAGTGATTAACGAAAACGAAGAAAATAAGCGTATCTCTATCTGGCTGGATACCTATTAT
CCGCAGCTGGCTTATTATCGGATTCATTTCGATGAGCCGCGTAAACCCGTTTTCTGGCTAAGCCGCCAGCGAAACACGAT
GAGCAAGAAAGAGCTCGAGGTGTTAAGTCAAAAGCTGAGAGCGCTAATGCCTTACGCGGATTCGGTTAACATCACGTTGA
TGGACGATGTTACCGCAGCAGGCCAGGCGGAAGCGGGGCTAAAACAGCAGGCGTTACCTTATTCCCGCAGGAATCATAAG
GGGGGCGTAACGTTTGTTATTCAGGGGGCGCTCGATGATGTAGAAATACTCAGAGCCCGTCAATTTGTCGATAGCTATTA
CCGCACATGGGGAGGACGCTATGTGCAGTTTGCGATCGAATTAAAAGATGACTGGCTCAAGGGGCGCTCATTTCAGTACG
GGGCGGAAGGTTATATCAAAATGAGCCCAGGCCATTGGTATTTCCCAAGCCCACTTTAA

Upstream 100 bases:

>100_bases
ATTTTATTTCTCACTTTTCATTCTATTTTCATCAGGAATCCCTGTGTCCTGTGCGGTAATCTGCTGCTATCGAGAACGAC
AGACATCGCTAACAGTATAT

Downstream 100 bases:

>100_bases
TTTAACGTAAATAAGGAAGTCATTATGGCAACACCTTGGTCAGGCTATCTGGATGACGTCTCAGCAAAATTTGATACGGG
CGTTGATAATCTACAAACGC

Product: needle complex inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSDALTASGQLPDIPADSFFIPLDHGGVNFEIQVDTDAT
EIILHELKEGNSESRSVQLNTPIQVGELLILIRPESEPWVPEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTL
WILNSPQRQAAELDSLLGQEKERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDKNARVINENEENKRISIWLDTYY
PQLAYYRIHFDEPRKPVFWLSRQRNTMSKKELEVLSQKLRALMPYADSVNITLMDDVTAAGQAEAGLKQQALPYSRRNHK
GGVTFVIQGALDDVEILRARQFVDSYYRTWGGRYVQFAIELKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL

Sequences:

>Translated_392_residues
METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSDALTASGQLPDIPADSFFIPLDHGGVNFEIQVDTDAT
EIILHELKEGNSESRSVQLNTPIQVGELLILIRPESEPWVPEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTL
WILNSPQRQAAELDSLLGQEKERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDKNARVINENEENKRISIWLDTYY
PQLAYYRIHFDEPRKPVFWLSRQRNTMSKKELEVLSQKLRALMPYADSVNITLMDDVTAAGQAEAGLKQQALPYSRRNHK
GGVTFVIQGALDDVEILRARQFVDSYYRTWGGRYVQFAIELKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL
>Mature_392_residues
METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSDALTASGQLPDIPADSFFIPLDHGGVNFEIQVDTDAT
EIILHELKEGNSESRSVQLNTPIQVGELLILIRPESEPWVPEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTL
WILNSPQRQAAELDSLLGQEKERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDKNARVINENEENKRISIWLDTYY
PQLAYYRIHFDEPRKPVFWLSRQRNTMSKKELEVLSQKLRALMPYADSVNITLMDDVTAAGQAEAGLKQQALPYSRRNHK
GGVTFVIQGALDDVEILRARQFVDSYYRTWGGRYVQFAIELKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL

Specific function: Required for invasion of epithelial cells

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRGH_SALTY (P41783)

Other databases:

- EMBL:   U21676
- EMBL:   AE006468
- PIR:   S69788
- RefSeq:   NP_461795.1
- PDB:   3GR0
- PDB:   3GR1
- PDBsum:   3GR0
- PDBsum:   3GR1
- PRIDE:   P41783
- GeneID:   1254397
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2874
- NMPDR:   fig|99287.1.peg.2772
- HOGENOM:   HBG390911
- OMA:   PGDFEVD
- ProtClustDB:   PRK15327
- BioCyc:   STYP99287:STM2874-MONOMER
- GO:   GO:0009405
- InterPro:   IPR013387
- InterPro:   IPR019029
- TIGRFAMs:   TIGR02554

Pfam domain/function: PF09480 PrgH

EC number: NA

Molecular weight: Translated: 44460; Mature: 44460

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10f3b09c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSDALTASGQLPDIPADSF
CCCCCCCEECCCCHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCEEECCCCCCCCCCCE
FIPLDHGGVNFEIQVDTDATEIILHELKEGNSESRSVQLNTPIQVGELLILIRPESEPWV
EEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCEEECEEEEEEECCCCCCC
PEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTLWILNSPQRQAAELDSLLGQE
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCC
KERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDKNARVINENEENKRISIWLDTYY
CHHEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEECCC
PQLAYYRIHFDEPRKPVFWLSRQRNTMSKKELEVLSQKLRALMPYADSVNITLMDDVTAA
CCEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
GQAEAGLKQQALPYSRRNHKGGVTFVIQGALDDVEILRARQFVDSYYRTWGGRYVQFAIE
CCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEE
LKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL
EECHHHCCCCEEECCCCEEEECCCCEECCCCH
>Mature Secondary Structure
METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSDALTASGQLPDIPADSF
CCCCCCCEECCCCHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCEEECCCCCCCCCCCE
FIPLDHGGVNFEIQVDTDATEIILHELKEGNSESRSVQLNTPIQVGELLILIRPESEPWV
EEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCEEECEEEEEEECCCCCCC
PEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTLWILNSPQRQAAELDSLLGQE
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCC
KERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDKNARVINENEENKRISIWLDTYY
CHHEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEECCC
PQLAYYRIHFDEPRKPVFWLSRQRNTMSKKELEVLSQKLRALMPYADSVNITLMDDVTAA
CCEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
GQAEAGLKQQALPYSRRNHKGGVTFVIQGALDDVEILRARQFVDSYYRTWGGRYVQFAIE
CCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEE
LKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL
EECHHHCCCCEEECCCCEEEECCCCEECCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609