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The map label for this gene is hypD [H]

Identifier: 16766163

GI number: 16766163

Start: 3001358

End: 3002476

Strand: Direct

Name: hypD [H]

Synonym: STM2857

Alternate gene names: 16766163

Gene position: 3001358-3002476 (Clockwise)

Preceding gene: 16766162

Following gene: 39546350

Centisome position: 61.79

GC content: 58.0

Gene sequence:

>1119_bases
ATGCGTTTTGTTGACGAGTACCGTGCGCCGGAACAGGTAATGCAGCTCATTGAACACCTGCGTGAACGCGCCGCCCTTCT
TCCTTACACTGCCGAACGACCGCTGCGCATTATGGAAGTCTGCGGGGGTCATACCCACGCGATTTTTAAATTTGGTCTCG
ATCAGTTACTGCCCGAAAACGTGGAGTTTATTCACGGCCCCGGTTGTCCGGTCTGCGTGCTGCCAATGGGACGCATCGAC
AGTTGCGTGGAAATCGCCAGCCATCCGGAGGTGATTTTCTGCACCTTTGGCGATGCCATGCGCGTGCCGGGGAAACAGGG
TTCTCTGTTGCAGGCTAAAGCGCGCGCGGATGTGCGTATTGTTTATTCTCCGATGGACGCGCTGAAGCTGGCGCAGGATA
ACCCGACCCGCAAAGTGGTATTTTTCGGGCTGGGCTTTGAAACCACCATGCCGACCACCGCCATCACGCTGCAGCAGGCA
AAACAGCGTGACGTGCGAAACTTCTACTTTTTTTGCCAGCACATTACGCTGATCCCGACGCTGCGTAGCCTACTGGAGCA
GCCGGACAACGGCATTGACGCCTTTCTTGCGCCAGGCCACGTCAGCATGGTCATCGGCACCGAGGCGTACCAGTTTATCG
CCGCCGATTTTCATCGCCCGCTGGTGGTGGCTGGATTCGAACCGCTTGATCTACTGCAAGGCGTGGTCATGCTGGTTGAG
CAGAAAATAGCGGCCCTAAGCCAGGTTGAAAATCAATACCGTCGCGTGGTGCCGGATGCCGGAAACATGCTGGCGCAGCA
GGCCATTGCCGATGTGTTCTGCGTTAATGGCGATAGCGAGTGGCGCGGTCTGGGCGTGATTGAATCCTCCGGCGTCCACC
TGACGCCGGAGTATCAGCGCTTTGACGCCGAAGCGCATTTCCGCCCAGCGCCGCAGCAGGTCTATGACGATCCGCGCGCC
CGCTGCGGCGAAGTGCTGACCGGCAGATGCAAGCCGCATCAGTGCCCGCTATTTGGTAAAACATGTAATCCAGAGACCGC
GTTCGGCGCGCTGATGGTCTCTTCCGAAGGCGCATGCGCCGCCTGGTATCAGTATCGTCAGCAGGAGTGTGAAGTTTGA

Upstream 100 bases:

>100_bases
TCATTAACGAAGCGGAAGCGCGCGACACGCTCGACGCGCTACAAAATATGTTTGATGTTGAGCCGGACGTCGGCGCACTG
CTGTATGGTGAGGAGAGATA

Downstream 100 bases:

>100_bases
ACAATATACAACTCGCCCACGGCAGCGGCGGCCAGGCTATGCAACAGTTGATTAATAGCCTGTTTATGGAGGCCTTTGCC
AACCCGTGGCTGGCGGAACA

Product: hydrogenase formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
SCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQA
KQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLVE
QKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPRA
RCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV

Sequences:

>Translated_372_residues
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
SCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQA
KQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLVE
QKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPRA
RCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV
>Mature_372_residues
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
SCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQA
KQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLVE
QKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPRA
RCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=372, Percent_Identity=94.3548387096774, Blast_Score=729, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41502; Mature: 41502

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCHHHHCCCC
VEFIHGPGCPVCVLPMGRIDSCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARADVRI
CCEEECCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEECCCCCEEE
VYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQAKQRDVRNFYFFCQHITLIPT
EECCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLVE
HHHHHHCCCCCCCEEECCCEEEEEECCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
QKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCCEECCHHHH
FDAEAHFRPAPQQVYDDPRARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACA
CCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCHH
AWYQYRQQECEV
HHHHHHHHHCCC
>Mature Secondary Structure
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCHHHHCCCC
VEFIHGPGCPVCVLPMGRIDSCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARADVRI
CCEEECCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEECCCCCEEE
VYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQAKQRDVRNFYFFCQHITLIPT
EECCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLVE
HHHHHHCCCCCCCEEECCCEEEEEECCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
QKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCCEECCHHHH
FDAEAHFRPAPQQVYDDPRARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACA
CCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCHH
AWYQYRQQECEV
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]