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The map label for this gene is hypE [H]

Identifier: 39546350

GI number: 39546350

Start: 3002473

End: 3003483

Strand: Direct

Name: hypE [H]

Synonym: STM2858

Alternate gene names: 39546350

Gene position: 3002473-3003483 (Clockwise)

Preceding gene: 16766163

Following gene: 16766165

Centisome position: 61.81

GC content: 59.35

Gene sequence:

>1011_bases
TTGAACAATATACAACTCGCCCACGGCAGCGGCGGCCAGGCTATGCAACAGTTGATTAATAGCCTGTTTATGGAGGCCTT
TGCCAACCCGTGGCTGGCGGAACAAGAAGATCAGGCGCGTCTGGAGCTGGCGCAGCTGACGGCGGAGGGCGACCGTCTGG
CGTTTTCTACCGATAGCTATGTGATCGATCCGCTCTTTTTCCCCGGCGGCAATATCGGCAAACTGGCGATTTGCGGTACG
GCGAACGACGTTGCGGTGAGCGGCGCGATCCCCCGCTATCTCTCCTGCGGCTTTATCCTTGAAGAAGGGCTGCCGATGGA
GACGTTAAAAAGCGTGGTCAATAGCATGGCGGCGACCGCGCGGGAAGCGGATATCGCCATTGTAACCGGCGACACCAAAG
TTGTGCAGCGCGGCGCGGCGGATAAATTATTTATCAACACTGCCGGCATGGGGGCGATTCCCGCCGATATTCGCTGGGGC
GCGCAAACGCTGAGCGTTGGCGATGTGCTGTTAGTCAGCGGTACGCTTGGCGATCACGGCGCCACTATCCTCAACCTGCG
TGAGCAACTGGGACTGGATGGCGAGCTGGCGAGCGACTGCGCAGTATTAACGCCGCTTATTCAGACGCTGCGTCATATTG
ACGGAGTGAAGGCATTGCGTGACGCCACGCGCGGCGGCGTGAATGCGGTCGCCCATGAGTTTGCGGCGTCCTGCGGTTAC
GGTATTGAATTGTCCGAATCCGCACTGCCGCTCAAACCTGCCGTGCGCGGCGTCTGCGAGCTGTTGGGGCTGGATGCCCT
GAACTTTGCCAACGAAGGAAAACTGGTGATTGCCGTTGAACGGCAGGCCGCAGATCGGGCGTTGGCGGCATTACGCGCGC
ATCCGCTGGGACGTGATGCGGCGCTGATTGGCGAAGTCGTGGAACGCAAAGGCGTTCGCTTAGCCGGACTCTATGGCGTG
AAGCGAACCCTTGATTTGCCACACGCCGAACCATTACCTCGTATATGCTAG

Upstream 100 bases:

>100_bases
GTAAAACATGTAATCCAGAGACCGCGTTCGGCGCGCTGATGGTCTCTTCCGAAGGCGCATGCGCCGCCTGGTATCAGTAT
CGTCAGCAGGAGTGTGAAGT

Downstream 100 bases:

>100_bases
CAGCCTGTTGACAGCATACTGTAAGCCGGATAAGACGCATTTGCGTCGACATCCGGCATTAACGCTGCATGAACGCCTGA
TGGCGCTTTGCTTATCAGGC

Product: hydrogenase formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELAQLTAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKSVVNSMAATAREADIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIRWG
AQTLSVGDVLLVSGTLGDHGATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKALRDATRGGVNAVAHEFAASCGY
GIELSESALPLKPAVRGVCELLGLDALNFANEGKLVIAVERQAADRALAALRAHPLGRDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC

Sequences:

>Translated_336_residues
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELAQLTAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKSVVNSMAATAREADIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIRWG
AQTLSVGDVLLVSGTLGDHGATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKALRDATRGGVNAVAHEFAASCGY
GIELSESALPLKPAVRGVCELLGLDALNFANEGKLVIAVERQAADRALAALRAHPLGRDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC
>Mature_336_residues
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELAQLTAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKSVVNSMAATAREADIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIRWG
AQTLSVGDVLLVSGTLGDHGATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKALRDATRGGVNAVAHEFAASCGY
GIELSESALPLKPAVRGVCELLGLDALNFANEGKLVIAVERQAADRALAALRAHPLGRDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=336, Percent_Identity=91.9642857142857, Blast_Score=623, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35323; Mature: 35323

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELAQLTAEGDRLAFSTDSY
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCE
VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKSVVNSMAATA
EECEEECCCCCCCEEEEECCCCCEEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHH
READIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIRWGAQTLSVGDVLLVSGTLGDHG
CCCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEEECCCCCCC
ATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKALRDATRGGVNAVAHEFAASCGY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GIELSESALPLKPAVRGVCELLGLDALNFANEGKLVIAVERQAADRALAALRAHPLGRDA
CCEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCHH
ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC
HHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELAQLTAEGDRLAFSTDSY
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCE
VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKSVVNSMAATA
EECEEECCCCCCCEEEEECCCCCEEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHH
READIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIRWGAQTLSVGDVLLVSGTLGDHG
CCCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEEECCCCCCC
ATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKALRDATRGGVNAVAHEFAASCGY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GIELSESALPLKPAVRGVCELLGLDALNFANEGKLVIAVERQAADRALAALRAHPLGRDA
CCEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCHH
ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC
HHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]