Click here to switch to the map view.

The map label for this gene is yehV

Identifier: 16765490

GI number: 16765490

Start: 2256368

End: 2257099

Strand: Direct

Name: yehV

Synonym: STM2160

Alternate gene names: 16765490

Gene position: 2256368-2257099 (Clockwise)

Preceding gene: 16765486

Following gene: 16765491

Centisome position: 46.45

GC content: 54.37

Gene sequence:

>732_bases
ATGGCGCTTTACACAATTGGTGAAGTGGCTTTGCTTTGTGATATCAATCCTGTCACGTTGCGCGCGTGGCAGAGACGTTA
TGGACTTTTAAAACCACAGCGAACGGATGGCGGTCATCGTCTGTTTAACGATGCCGATATCGACAGAATCCGCGAAATCA
AGCGCTGGATAGATAACGGCGTCCAGGTCAGCAAAGTCAAAGTGCTGCTCAGTAGCGACAGTAGCGAACAACCTAACGGC
TGGCGCGAACAGCAGGAGATCCTGCTGCACTACCTGCAAAGCAGTAATCTGCACAGTTTACGGTTATGGGTCAAAGAACG
CGGTCAGGATTATCCTGCCCAAACATTGACCACTAACCTGTTCGTCCCACTGCGGCGACGATTACAGTGCCAACAACCCG
CCCTTCAGGCGCTGCTCGGCATTCTTGACGGTATCCTGATCAACTATATTGCGCTCTGCCTGGCGTCTGCGCGTAAGAAA
CAGGGAAAAGATGCGTTGGTGATCGGCTGGAATATCCATGATACCACCCGCCTGTGGCTGGAAGGTTGGGTCGCCAGCCA
ACAGGGATGGCGAATCGACGTGCTGGCGCATTCGCTTAGCCAGTTCCGCCCGGAACTGTTTGACGGCAAGACGTTACTGG
TATGGTGCGGAGAAAACCAGACGCTGGCGCAGCAGCAGCAACTCCTGGCATGGCGCGCCCAGGGACGCGACATTCATCCC
CTTGGCGTTTAA

Upstream 100 bases:

>100_bases
CGCTACTTCGCGTTTTAATGCATAAAAAACAGGCAAAACTTCCTGGTTCCTAAAAGAGCGTCTAAAGTTAAACCGGGACC
TCGCGAGCAAGGGTGAAACG

Downstream 100 bases:

>100_bases
ACAGAAGCTAACAAATTCGCTTTAATGTATACTCCTTTTATTAACATAAGGAGTACATAATGCGCGTAGCGAAAATCGGG
GTGATCGCCCTTTTCCTGCT

Product: transcriptional repressor

Products: NA

Alternate protein names: MerR-like regulator A

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKVLLSSDSSEQPNG
WREQQEILLHYLQSSNLHSLRLWVKERGQDYPAQTLTTNLFVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKK
QGKDALVIGWNIHDTTRLWLEGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGENQTLAQQQQLLAWRAQGRDIHP
LGV

Sequences:

>Translated_243_residues
MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKVLLSSDSSEQPNG
WREQQEILLHYLQSSNLHSLRLWVKERGQDYPAQTLTTNLFVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKK
QGKDALVIGWNIHDTTRLWLEGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGENQTLAQQQQLLAWRAQGRDIHP
LGV
>Mature_242_residues
ALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKVLLSSDSSEQPNGW
REQQEILLHYLQSSNLHSLRLWVKERGQDYPAQTLTTNLFVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKKQ
GKDALVIGWNIHDTTRLWLEGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGENQTLAQQQQLLAWRAQGRDIHPL
GV

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF)

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788448, Length=243, Percent_Identity=85.1851851851852, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787409, Length=238, Percent_Identity=47.0588235294118, Blast_Score=227, Evalue=5e-61,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): MLRA_SALTY (P58398)

Other databases:

- EMBL:   AF288175
- EMBL:   AE006468
- RefSeq:   NP_461105.1
- ProteinModelPortal:   P58398
- SMR:   P58398
- GeneID:   1253682
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2160
- HOGENOM:   HBG417247
- OMA:   WLEAWIA
- ProtClustDB:   PRK15043
- BioCyc:   STYP99287:STM2160-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR000551
- SMART:   SM00422

Pfam domain/function: PF00376 MerR; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 27903; Mature: 27771

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFNDADIDRIREIKRWIDNG
CCEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VQVSKVKVLLSSDSSEQPNGWREQQEILLHYLQSSNLHSLRLWVKERGQDYPAQTLTTNL
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHH
FVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKKQGKDALVIGWNIHDTTRLWL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
EGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGENQTLAQQQQLLAWRAQGRDIHP
HHHHCCCCCCCHHHHHHHHHHHCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCC
LGV
CCC
>Mature Secondary Structure 
ALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFNDADIDRIREIKRWIDNG
CEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VQVSKVKVLLSSDSSEQPNGWREQQEILLHYLQSSNLHSLRLWVKERGQDYPAQTLTTNL
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHH
FVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKKQGKDALVIGWNIHDTTRLWL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
EGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGENQTLAQQQQLLAWRAQGRDIHP
HHHHCCCCCCCHHHHHHHHHHHCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCC
LGV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 11677609