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The map label for this gene is rfbP

Identifier: 16765412

GI number: 16765412

Start: 2160931

End: 2162361

Strand: Reverse

Name: rfbP

Synonym: STM2082

Alternate gene names: 16765412

Gene position: 2162361-2160931 (Counterclockwise)

Preceding gene: 16765413

Following gene: 16765411

Centisome position: 44.52

GC content: 37.11

Gene sequence:

>1431_bases
ATGGATAATATTGATAATAAGTATAATCCACAGCTATGTAAAATTTTTTTGGCTATATCGGATTTGATTTTTTTTAATTT
AGCCTTATGGTTTTCATTAGGATGTGTCTATTTTATTTTTGATCAAGTACAGCGATTTATTCCTCAAGACCAATTAGATA
CAAGAGTTATTACGCATTTTATTTTGTCAGTAGTATGTGTCGGTTGGTTTTGGATTCGTTTGCGACATTATACATACCGC
AAGCCATTTTGGTATGAGTTAAAAGAAATTTTTCGTACGATCGTTATTTTTGCTATATTTGATTTGGCTCTGATAGCGTT
TACAAAATGGCAGTTTTCACGCTATGTCTGGGTGTTTTGTTGGACTTTTGCCCTAATCCTGGTGCCTTTTTTTCGCGCAC
TTACAAAGCATTTATTGAACAAGCTAGGTATCTGGAAGAAAAAAACTATCATCCTGGGGAGCGGACAGAATGCTCGTGGT
GCATATTCTGCGCTGCAAAGTGAGGAGATGATGGGGTTTGATGTTATCGCTTTTTTTGATACGGATGCGTCAGATGCTGA
AATAAATATGTTGCCGGTGATAAAGGATACTGAGATTATTTGGGATTTAAATCGTACAGGTGATGTCCATTATATCCTTG
CTTATGAATACACCGAGTTGGAGAAAACACATTTTTGGCTACGTGAACTTTCAAAACATCATTGTCGTTCTGTTACTGTA
GTCCCCTCGTTTAGAGGATTGCCATTATATAATACTGATATGTCTTTTATCTTTAGCCATGAAGTTATGTTATTAAGGAT
ACAAAATAACTTGGCTAAAAGGTCGTCCCGTTTTCTCAAACGGACATTTGATATTGTTTGTTCAATAATGATTCTTATAA
TTGCATCACCACTTATGATTTATCTGTGGTATAAAGTTACTCGAGATGGTGGTCCGGCTATTTATGGTCACCAGCGAGTA
GGTCGGCATGGAAAACTTTTTCCATGCTACAAATTTCGTTCTATGGTTATGAATTCTCAAGAGGTACTAAAAGAACTTTT
GGCTAACGATCCTATTGCCAGGGCTGAATGGGAGAAAGATTTTAAACTGAAAAATGATCCTCGAATCACAGCTGTAGGTC
GATTTATACGTAAAACTAGCCTTGATGAGTTGCCACAACTTTTTAATGTACTAAAAGGTGATATGAGCCTGGTTGGACCA
CGACCTATCGTTTCGGATGAACTGGAGCGTTATTGTGATGATGTTGATTATTATTTGATGGCAAAGCCGGGCATGACAGG
TCTATGGCAAGTGAGTGGGCGTAATGATGTTGATTATGACACTCGTGTTTATTTTGATTCCTGGTATGTTAAAAACTGGA
CGCTTTGGAATGATATTGCCATTCTGTTTAAAACAGCGAAAGTTGTTTTGCGGCGAGATGGTGCGTATTAA

Upstream 100 bases:

>100_bases
CTAATATTAAAAAACGATGCTTGCTGTAAAAAAATTGAATGTTATTTACTTAATATGCCTATTTTATTTACATTATGCAC
GGTCAGAGGGTGAGGATTAA

Downstream 100 bases:

>100_bases
GCTTACCGAGAAGTACTGAATAATAATTGTATAAATTAGCCTGCGTAAAATCTGAACGCATCAATCGCTACCTTAATATC
ATACCTTTGAGTTAACATAC

Product: undecaprenol-phosphate galactosephosphotransferase/O-antigen transferase

Products: NA

Alternate protein names: Galactosyl-P-P-undecaprenol synthase

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQRFIPQDQLDTRVITHFILSVVCVGWFWIRLRHYTYR
KPFWYELKEIFRTIVIFAIFDLALIAFTKWQFSRYVWVFCWTFALILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARG
AYSALQSEEMMGFDVIAFFDTDASDAEINMLPVIKDTEIIWDLNRTGDVHYILAYEYTELEKTHFWLRELSKHHCRSVTV
VPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSSRFLKRTFDIVCSIMILIIASPLMIYLWYKVTRDGGPAIYGHQRV
GRHGKLFPCYKFRSMVMNSQEVLKELLANDPIARAEWEKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGP
RPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYDTRVYFDSWYVKNWTLWNDIAILFKTAKVVLRRDGAY

Sequences:

>Translated_476_residues
MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQRFIPQDQLDTRVITHFILSVVCVGWFWIRLRHYTYR
KPFWYELKEIFRTIVIFAIFDLALIAFTKWQFSRYVWVFCWTFALILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARG
AYSALQSEEMMGFDVIAFFDTDASDAEINMLPVIKDTEIIWDLNRTGDVHYILAYEYTELEKTHFWLRELSKHHCRSVTV
VPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSSRFLKRTFDIVCSIMILIIASPLMIYLWYKVTRDGGPAIYGHQRV
GRHGKLFPCYKFRSMVMNSQEVLKELLANDPIARAEWEKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGP
RPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYDTRVYFDSWYVKNWTLWNDIAILFKTAKVVLRRDGAY
>Mature_476_residues
MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQRFIPQDQLDTRVITHFILSVVCVGWFWIRLRHYTYR
KPFWYELKEIFRTIVIFAIFDLALIAFTKWQFSRYVWVFCWTFALILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARG
AYSALQSEEMMGFDVIAFFDTDASDAEINMLPVIKDTEIIWDLNRTGDVHYILAYEYTELEKTHFWLRELSKHHCRSVTV
VPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSSRFLKRTFDIVCSIMILIIASPLMIYLWYKVTRDGGPAIYGHQRV
GRHGKLFPCYKFRSMVMNSQEVLKELLANDPIARAEWEKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGP
RPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYDTRVYFDSWYVKNWTLWNDIAILFKTAKVVLRRDGAY

Specific function: Is responsible for transferring galactose-1-phosphate to the lipid precursor undecaprenol phosphate in the first steps of O-polysaccharide biosynthesis

COG id: COG2148

COG function: function code M; Sugar transferases involved in lipopolysaccharide synthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial sugar transferase family

Homologues:

Organism=Escherichia coli, GI1788360, Length=400, Percent_Identity=27, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RFBP_SALTY (P26406)

Other databases:

- EMBL:   X56793
- EMBL:   AE006468
- PIR:   S15314
- RefSeq:   NP_461027.1
- ProteinModelPortal:   P26406
- PRIDE:   P26406
- GeneID:   1253603
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2082
- NMPDR:   fig|99287.1.peg.2007
- HOGENOM:   HBG695824
- OMA:   SLWNDIA
- ProtClustDB:   PRK15204
- BioCyc:   STYP99287:STM2082-MONOMER
- BRENDA:   2.7.8.6
- InterPro:   IPR003362
- InterPro:   IPR017475
- InterPro:   IPR017472
- TIGRFAMs:   TIGR03025
- TIGRFAMs:   TIGR03022

Pfam domain/function: PF02397 Bac_transf

EC number: =2.7.8.6

Molecular weight: Translated: 56198; Mature: 56198

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf7a1080)-; HASH(0xfbe98c8)-; HASH(0xf06e1f4)-; HASH(0xf28f000)-; HASH(0xfbcac48)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQRFIPQDQLDTRVITHF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ILSVVCVGWFWIRLRHYTYRKPFWYELKEIFRTIVIFAIFDLALIAFTKWQFSRYVWVFC
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTFALILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARGAYSALQSEEMMGFDVIAFFD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEC
TDASDAEINMLPVIKDTEIIWDLNRTGDVHYILAYEYTELEKTHFWLRELSKHHCRSVTV
CCCCCCEEEEEEEEECCEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCEEEE
VPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSSRFLKRTFDIVCSIMILIIASPLMI
ECCCCCCEEECCCHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLWYKVTRDGGPAIYGHQRVGRHGKLFPCYKFRSMVMNSQEVLKELLANDPIARAEWEKD
HHHHHEECCCCCEEECCHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHCCCCC
FKLKNDPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGPRPIVSDELERYCDDVDYYLM
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCEEEE
AKPGMTGLWQVSGRNDVDYDTRVYFDSWYVKNWTLWNDIAILFKTAKVVLRRDGAY
ECCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQRFIPQDQLDTRVITHF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ILSVVCVGWFWIRLRHYTYRKPFWYELKEIFRTIVIFAIFDLALIAFTKWQFSRYVWVFC
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTFALILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARGAYSALQSEEMMGFDVIAFFD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEC
TDASDAEINMLPVIKDTEIIWDLNRTGDVHYILAYEYTELEKTHFWLRELSKHHCRSVTV
CCCCCCEEEEEEEEECCEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCEEEE
VPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSSRFLKRTFDIVCSIMILIIASPLMI
ECCCCCCEEECCCHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLWYKVTRDGGPAIYGHQRVGRHGKLFPCYKFRSMVMNSQEVLKELLANDPIARAEWEKD
HHHHHEECCCCCEEECCHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHCCCCC
FKLKNDPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGPRPIVSDELERYCDDVDYYLM
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCEEEE
AKPGMTGLWQVSGRNDVDYDTRVYFDSWYVKNWTLWNDIAILFKTAKVVLRRDGAY
ECCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609