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The map label for this gene is yeeO [H]

Identifier: 16765344

GI number: 16765344

Start: 2094377

End: 2095834

Strand: Reverse

Name: yeeO [H]

Synonym: STM2013

Alternate gene names: 16765344

Gene position: 2095834-2094377 (Counterclockwise)

Preceding gene: 16765345

Following gene: 16765343

Centisome position: 43.15

GC content: 53.5

Gene sequence:

>1458_bases
ATGTGGTTTCAACTCTCTTCTTTAAGGTCCATTTTGAACGTCTCCACTGCCTTACGCCAGGCTGTCGTCCGTACGCCCTG
GTATGCCAAACGCAAGAGCTACAAAGTGTTGTTCTGGCGTGAAATCACCCCACTTGCTATCCCTATTTTTCTGGAAAATA
CCTGTGTTTTGCTAATGGGCGTGCTCAGTACTTTTCTCGTCAGTTGGCTGGGCAAGGAAGCAATGGCGGGCGTGGGGCTT
GCCGACAGTTTTAATATGGTAATTATGGCTTTTTTTGCGGCTATCGATCTTGGTACTACGGTGGTGGTCGCCTTTAGCCT
CGGCAAGCGCGACAGGCGACGCGCAAGGGCGGCGGCGCGCCAGTCGCTGGTGATTATGACGCTATTTGCCGTTGTGCTGG
CAGTGGTCATTCATTATTTCGGCAGTGAAATTATTAATATTGTCGCAGGCGAGGCGACGCCAGAAGTAAAGGGGCTGGCG
TTAACGTACCTTGAACTGACGGTGCTGAGTTATCCGGCTGCGGCAATTGCGCTAATCGGTAGCGGCGCGCTGCGTGGGGC
AGGGAATACGAAAATCCCGTTGATGATTAACGGCGGGATGAACATTCTCAATATTATTATCAGCAGCATCCTGATTTACG
GGGCTTTCTCCTGGCAAGGGCTGGGTTTTGCCGGCGCGGGGCTGGGATTAACCATTTCGCGCTACATCGGCGCGGTAGCG
ATTATTTGGGTGCTGATGATTGGTTTTAATCCGGCGCTGCGCATTCCGCTGAAAAGCTATCTGAAGCCGCTGAATTTCGG
CATTATCTGGGAAGTGATGGGTATCGGTATTCCGGCGAGCATTGAATCAGTGCTGTTCAACGGTGGCAAGCTACTGACGC
AAATGTTTGTCGCCGGAATGGGCACTAACGTTATTGCGGGTAACTTTATTGCCTTTTCCGTGGCGGCGCTTATCAACCTG
CCGGGTAACGCCCTTGGTTCGGCGTCGACTATTATCACCGGTAAGCGTCTTGGTACCGGGCAAATTGGTCAGGCAGAGCG
TCAACTGCGCCATGTATTCTGGATGTCGACTATCGTACTTACGGCAATTGCCTGGGGGACGGCGCCGTTTGCGGGTCTGT
TTGCCTCATTTTATACCCAGGAGCAGGACGTAAAAGAGGTAGTGAAAGTTCTGCTCTGGCTTAATGCTGCCTTTATGCCA
ATTTGGGCGGCCGCGTGGGTGTTGCCGTCGGGTTTTAAAGGCGCGCGCGATGTGCGATTTGCGATGTGGGTATCGATGCT
GGGGATGTGGGGCTGTCGCGTTGTGGCAGGGTATACGCTTGGTATTGTGCTGGGTATGGGGGTTGTAGGGGTTTGGCTGG
GGATGTTTCTTGACTGGGCCGTGCGTGGCGCACTGTTTTACTGGCGTCTGATAAGCGGGCGCTGGCTGTGGAGATACCCG
CGCGTAAAGAGGGAGTAA

Upstream 100 bases:

>100_bases
TACAGATTCGATTGCGGGTTATCTCATCACTTTGTTGCATTTGCAGACATTTTTTCTGCAAAAAGCTTTGCAGCCTTACG
ATTTCTCGCTCATTATTGAA

Downstream 100 bases:

>100_bases
GCGCTTTTTGCTGTGAAAATCATCAGGAAACGGTGAATTTTAACCGAAGTGTGGAATAAAGCAGCAAACGAACTTTTTTT
GTGAAAACAGGCTTTGACAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MWFQLSSLRSILNVSTALRQAVVRTPWYAKRKSYKVLFWREITPLAIPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGL
ADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLA
LTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLMINGGMNILNIIISSILIYGAFSWQGLGFAGAGLGLTISRYIGAVA
IIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVAALINL
PGNALGSASTIITGKRLGTGQIGQAERQLRHVFWMSTIVLTAIAWGTAPFAGLFASFYTQEQDVKEVVKVLLWLNAAFMP
IWAAAWVLPSGFKGARDVRFAMWVSMLGMWGCRVVAGYTLGIVLGMGVVGVWLGMFLDWAVRGALFYWRLISGRWLWRYP
RVKRE

Sequences:

>Translated_485_residues
MWFQLSSLRSILNVSTALRQAVVRTPWYAKRKSYKVLFWREITPLAIPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGL
ADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLA
LTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLMINGGMNILNIIISSILIYGAFSWQGLGFAGAGLGLTISRYIGAVA
IIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVAALINL
PGNALGSASTIITGKRLGTGQIGQAERQLRHVFWMSTIVLTAIAWGTAPFAGLFASFYTQEQDVKEVVKVLLWLNAAFMP
IWAAAWVLPSGFKGARDVRFAMWVSMLGMWGCRVVAGYTLGIVLGMGVVGVWLGMFLDWAVRGALFYWRLISGRWLWRYP
RVKRE
>Mature_485_residues
MWFQLSSLRSILNVSTALRQAVVRTPWYAKRKSYKVLFWREITPLAIPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGL
ADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLA
LTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLMINGGMNILNIIISSILIYGAFSWQGLGFAGAGLGLTISRYIGAVA
IIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVAALINL
PGNALGSASTIITGKRLGTGQIGQAERQLRHVFWMSTIVLTAIAWGTAPFAGLFASFYTQEQDVKEVVKVLLWLNAAFMP
IWAAAWVLPSGFKGARDVRFAMWVSMLGMWGCRVVAGYTLGIVLGMGVVGVWLGMFLDWAVRGALFYWRLISGRWLWRYP
RVKRE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=485, Percent_Identity=81.6494845360825, Blast_Score=798, Evalue=0.0,
Organism=Escherichia coli, GI48994890, Length=462, Percent_Identity=24.025974025974, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52823; Mature: 52823

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFQLSSLRSILNVSTALRQAVVRTPWYAKRKSYKVLFWREITPLAIPIFLENTCVLLMG
CCEEHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCEEEEEECCCCEEEEEHHHHHHHHHHH
VLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAAR
HHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHH
QSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLALTYLELTVLSYPAAAIALIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHC
SGALRGAGNTKIPLMINGGMNILNIIISSILIYGAFSWQGLGFAGAGLGLTISRYIGAVA
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGM
HHHHHHHCCCCCEECCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCC
GTNVIAGNFIAFSVAALINLPGNALGSASTIITGKRLGTGQIGQAERQLRHVFWMSTIVL
CCCHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
TAIAWGTAPFAGLFASFYTQEQDVKEVVKVLLWLNAAFMPIWAAAWVLPSGFKGARDVRF
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AMWVSMLGMWGCRVVAGYTLGIVLGMGVVGVWLGMFLDWAVRGALFYWRLISGRWLWRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
RVKRE
CCCCC
>Mature Secondary Structure
MWFQLSSLRSILNVSTALRQAVVRTPWYAKRKSYKVLFWREITPLAIPIFLENTCVLLMG
CCEEHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCEEEEEECCCCEEEEEHHHHHHHHHHH
VLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAAR
HHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHH
QSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLALTYLELTVLSYPAAAIALIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHC
SGALRGAGNTKIPLMINGGMNILNIIISSILIYGAFSWQGLGFAGAGLGLTISRYIGAVA
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGM
HHHHHHHCCCCCEECCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCC
GTNVIAGNFIAFSVAALINLPGNALGSASTIITGKRLGTGQIGQAERQLRHVFWMSTIVL
CCCHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
TAIAWGTAPFAGLFASFYTQEQDVKEVVKVLLWLNAAFMPIWAAAWVLPSGFKGARDVRF
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AMWVSMLGMWGCRVVAGYTLGIVLGMGVVGVWLGMFLDWAVRGALFYWRLISGRWLWRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
RVKRE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]