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The map label for this gene is tonB

Identifier: 16765081

GI number: 16765081

Start: 1831260

End: 1831988

Strand: Reverse

Name: tonB

Synonym: STM1737

Alternate gene names: 16765081

Gene position: 1831988-1831260 (Counterclockwise)

Preceding gene: 16765085

Following gene: 16765076

Centisome position: 37.72

GC content: 57.75

Gene sequence:

>729_bases
ATGACCCTTGATTTACCTCGTCGCTTTCCCTGGCCGACACTCCTTTCCGTAGGCATTCATGGTGCTGTAGTGGCAGGTTT
GCTCTATACCTCGGTACATCAGGTTATTGAATTGCCTGCGCCAGCGCAGCCTATCACGGTGACAATGGTTTCACCCGCTG
ACCTGGAGCCGCCCCAGGCGGTTCAGCCGCCGCCGGAGCCGGTGGTTGAACCCGAACCCGAACCGGAGCCAGAGCCGATC
CCTGAACCGCCTAAAGAAGCGCCCGTGGTGATTGAGAAACCCAAACCTAAGCCAAAACCCAAGCCAAAACCGAAACCGGT
GAAAAAGGTTGAAGAGCAGCCGAAGCGCGAAGTCAAACCAGCCGCGCCGCGTCCTGCCTCACCGTTTGAAAATAGCGCCC
CGGTGCGGCCAACAAGCAGCACCGCATCGGCGACCAGCAAGCCCGCGGTGAGCGTGCCCACTGGACCTCGCGCTCTGAGC
CGTAACCAGCCGCAGTATCCGGCGCGAGCACAGGCGTTACGTATTGAAGGCCGCGTAAAGGTGAAGTTTGACGTGACCTC
TGCTGGGCGAGTGGAAAATGTACAGATTCTATCCGCGCAGCCAGCCAATATGTTTGAGCGTGAAGTTAAGAATGCGATGC
GAAAATGGCGCTATGAAGCAGGCAAGCCGGGTTCCGGGCTGGTGGTCAATATTATCTTCCGTCTGAACGGTACGGCGCAG
ATTGAGTAA

Upstream 100 bases:

>100_bases
ATCTTTTAAATGCCGCTATCGGCAATGCCTTATTGAATATGATTGCTATTTGCATTTAAAATTCAGCTCTGGTTTTTCAA
CTGAAACGATTATGACTTCA

Downstream 100 bases:

>100_bases
TCTCTGGCGCCGCCAGCCAGGAATATACCATCACCTGCTGGCGGCGTAAGCGGGTATACTTAACCCTGAACCGGGAGCGG
GCGAGGTTTACCGTCCGGAT

Product: transport protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPEPI
PEPPKEAPVVIEKPKPKPKPKPKPKPVKKVEEQPKREVKPAAPRPASPFENSAPVRPTSSTASATSKPAVSVPTGPRALS
RNQPQYPARAQALRIEGRVKVKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
IE

Sequences:

>Translated_242_residues
MTLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPEPI
PEPPKEAPVVIEKPKPKPKPKPKPKPVKKVEEQPKREVKPAAPRPASPFENSAPVRPTSSTASATSKPAVSVPTGPRALS
RNQPQYPARAQALRIEGRVKVKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
IE
>Mature_241_residues
TLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPEPIP
EPPKEAPVVIEKPKPKPKPKPKPKPVKKVEEQPKREVKPAAPRPASPFENSAPVRPTSSTASATSKPAVSVPTGPRALSR
NQPQYPARAQALRIEGRVKVKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQI
E

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobac

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family

Homologues:

Organism=Escherichia coli, GI1787505, Length=243, Percent_Identity=83.1275720164609, Blast_Score=298, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TONB_SALTY (P25945)

Other databases:

- EMBL:   X56434
- EMBL:   AE006468
- PIR:   S13257
- RefSeq:   NP_460696.1
- ProteinModelPortal:   P25945
- SMR:   P25945
- GeneID:   1253256
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1737
- NMPDR:   fig|99287.1.peg.1683
- HOGENOM:   HBG473783
- OMA:   NSAPVRP
- ProtClustDB:   PRK10819
- BioCyc:   STYP99287:STM1737-MONOMER
- InterPro:   IPR003538
- InterPro:   IPR006260
- PRINTS:   PR01374
- TIGRFAMs:   TIGR01352

Pfam domain/function: PF03544 TonB

EC number: NA

Molecular weight: Translated: 26294; Mature: 26162

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xee37d9c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
VQPPPEPVVEPEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPKPVKKVEEQPKREVKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCC
AAPRPASPFENSAPVRPTSSTASATSKPAVSVPTGPRALSRNQPQYPARAQALRIEGRVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCHHEEEEECCEEE
VKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
EEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCEEE
IE
CH
>Mature Secondary Structure 
TLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
VQPPPEPVVEPEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPKPVKKVEEQPKREVKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCC
AAPRPASPFENSAPVRPTSSTASATSKPAVSVPTGPRALSRNQPQYPARAQALRIEGRVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCHHEEEEECCEEE
VKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
EEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCEEE
IE
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2266561; 8316087; 11677609