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The map label for this gene is chuR [H]

Identifier: 16764638

GI number: 16764638

Start: 1365225

End: 1366421

Strand: Direct

Name: chuR [H]

Synonym: STM1287

Alternate gene names: 16764638

Gene position: 1365225-1366421 (Clockwise)

Preceding gene: 16764637

Following gene: 16764639

Centisome position: 28.11

GC content: 49.96

Gene sequence:

>1197_bases
ATGAGCATAGTATTCAATACCGTAGCCAAGCCCAGCGGCAGTCTGTGTAACTTATCCTGCAAGTACTGTTTCTATCTTGA
TAAACCCCGGGGGCAGCGCGTCATGTCTGACGATGTGCTGGAGACGTATATCCGCCGGGTAATTGATGATACGCCATCCT
CAGAGGTCTCGTTTTGCTGGCAGGGGGGAGAGCCGACGCTATGCGGTCTTTCTTTTTACCAAAAAGTGGTGCGCTTGCAG
CAACGCTATGCCAACGGCAAAACTATCTACAACAGTCTGCAAACCAATGGCGTATTAATCAATGAAGAGTGGGCGGCTTT
CTTTGCGCAGCACCAGTTCCTGATTGGTATATCGATTGATGGGCCGCAAGTCGTTCATGATAATTACCGGAAAACGCCGT
CAGGGCGGGCGTCTTTTTCCCGAGTCGTTAATGCTATCCGCCTTCTGCAGGCAAATGATGTCGAGTTCAACACGCTCACT
GTCGTGAATGATGCGTCATGCTGTCATGGCAACGCTATTTATCATTTTTTGACGCAGGAACTGGAAAGTAAACACCTGCA
ATTTATTCCCATTGTTGAGCCGCTCGCGCAAAAAGCGCAGCGTTCTTTGACGTTATCTGACAATGAGGATTCGCCTTCGC
TGATGCCCTTTTCCGTCACGCCTGAAGGGTGGGGCGCCTTTATGTGCGATGTTTTTGATCAATGGATACGTCACGATGTC
GGACGCATATTCGTACAGCTTTTTGATAACTTACTTGGCGTCTGGATGGGGGAGCCCGCCACGCTTTGTACGATGCAGTC
GACCTGCGGACAAAGTTTGCTGGTGGAGCAGAATGGCGACGTGTTTAGCTGCGACCATTTTGTTTTTCCCGCCTATAAAC
TGGGCAATCTGCAGCAACACTCTTTAGAAGAAATGGCGGCCTCTCCTTTTCAGCAGCAGTTTGGCGCGGCTAAAGCAAAC
CTTTCCTCACGCTGCCAGAACTGTACGTGGCGCTTTGCCTGTCACGGCGGTTGTCCGAAACATCGAATTTGTATGGACGG
CGGCGAACGGCAAAATTATCTCTGTAAAGGATATCTGGAGTTCTTTCAACATGTGACGCCCTATATGAATGTGATGCGTC
AATTATTACTGAATCAGCGACCCGCCGCGCATATTACCCGCATCGTCGACATGATTGCGGATGACGTTCGTCAGTGA

Upstream 100 bases:

>100_bases
CTGCGCTAACAATTAGCGTAATAATTGTTGCAATGCTGGCTGATATCGCCCTGTCACGTCCCGCTTATGCTATACCCATT
CTTCACAGCGAGTAAGACGA

Downstream 100 bases:

>100_bases
CAAGAAAATCGCCCCCTTGCGCGGTATGATGCCGGACATTACCGTAGGGTCTAAGAGTCCTGTATTGTTTTACCGTCGAG
TGACATTGAAAAGGAAATGA

Product: arylsulfatase regulator

Products: NA

Alternate protein names: AnSME; Chondroitin sulfate/heparin utilization regulation protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYIRRVIDDTPSSEVSFCWQGGEPTLCGLSFYQKVVRLQ
QRYANGKTIYNSLQTNGVLINEEWAAFFAQHQFLIGISIDGPQVVHDNYRKTPSGRASFSRVVNAIRLLQANDVEFNTLT
VVNDASCCHGNAIYHFLTQELESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFSVTPEGWGAFMCDVFDQWIRHDV
GRIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVEQNGDVFSCDHFVFPAYKLGNLQQHSLEEMAASPFQQQFGAAKAN
LSSRCQNCTWRFACHGGCPKHRICMDGGERQNYLCKGYLEFFQHVTPYMNVMRQLLLNQRPAAHITRIVDMIADDVRQ

Sequences:

>Translated_398_residues
MSIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYIRRVIDDTPSSEVSFCWQGGEPTLCGLSFYQKVVRLQ
QRYANGKTIYNSLQTNGVLINEEWAAFFAQHQFLIGISIDGPQVVHDNYRKTPSGRASFSRVVNAIRLLQANDVEFNTLT
VVNDASCCHGNAIYHFLTQELESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFSVTPEGWGAFMCDVFDQWIRHDV
GRIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVEQNGDVFSCDHFVFPAYKLGNLQQHSLEEMAASPFQQQFGAAKAN
LSSRCQNCTWRFACHGGCPKHRICMDGGERQNYLCKGYLEFFQHVTPYMNVMRQLLLNQRPAAHITRIVDMIADDVRQ
>Mature_397_residues
SIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYIRRVIDDTPSSEVSFCWQGGEPTLCGLSFYQKVVRLQQ
RYANGKTIYNSLQTNGVLINEEWAAFFAQHQFLIGISIDGPQVVHDNYRKTPSGRASFSRVVNAIRLLQANDVEFNTLTV
VNDASCCHGNAIYHFLTQELESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFSVTPEGWGAFMCDVFDQWIRHDVG
RIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVEQNGDVFSCDHFVFPAYKLGNLQQHSLEEMAASPFQQQFGAAKANL
SSRCQNCTWRFACHGGCPKHRICMDGGERQNYLCKGYLEFFQHVTPYMNVMRQLLLNQRPAAHITRIVDMIADDVRQ

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract. May catalyze the activation of chondro-6- sulfatase, i

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=394, Percent_Identity=46.1928934010152, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI87081923, Length=393, Percent_Identity=42.4936386768448, Blast_Score=355, Evalue=3e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 45052; Mature: 44921

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYIRRVIDDTPSSEVSFCW
CCEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
QGGEPTLCGLSFYQKVVRLQQRYANGKTIYNSLQTNGVLINEEWAAFFAQHQFLIGISID
ECCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECHHHHHHHHCCEEEEEEECC
GPQVVHDNYRKTPSGRASFSRVVNAIRLLQANDVEFNTLTVVNDASCCHGNAIYHFLTQE
CCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHH
LESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFSVTPEGWGAFMCDVFDQWIRHDV
HHHCCCEEEEHHHHHHHHHHHCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
GRIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVEQNGDVFSCDHFVFPAYKLGNLQQH
HHHHHHHHHHHHHHHCCCCHHEEEEHHHCCCEEEEECCCCEEEECCEECCCHHCCCCHHH
SLEEMAASPFQQQFGAAKANLSSRCQNCTWRFACHGGCPKHRICMDGGERQNYLCKGYLE
HHHHHHCCHHHHHHCHHHHCHHHHHCCCEEEEEECCCCCCCCEECCCCCCCCHHHHHHHH
FFQHVTPYMNVMRQLLLNQRPAAHITRIVDMIADDVRQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYIRRVIDDTPSSEVSFCW
CEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
QGGEPTLCGLSFYQKVVRLQQRYANGKTIYNSLQTNGVLINEEWAAFFAQHQFLIGISID
ECCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECHHHHHHHHCCEEEEEEECC
GPQVVHDNYRKTPSGRASFSRVVNAIRLLQANDVEFNTLTVVNDASCCHGNAIYHFLTQE
CCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHH
LESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFSVTPEGWGAFMCDVFDQWIRHDV
HHHCCCEEEEHHHHHHHHHHHCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
GRIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVEQNGDVFSCDHFVFPAYKLGNLQQH
HHHHHHHHHHHHHHHCCCCHHEEEEHHHCCCEEEEECCCCEEEECCEECCCHHCCCCHHH
SLEEMAASPFQQQFGAAKANLSSRCQNCTWRFACHGGCPKHRICMDGGERQNYLCKGYLE
HHHHHHCCHHHHHHCHHHHCHHHHHCCCEEEEEECCCCCCCCEECCCCCCCCHHHHHHHH
FFQHVTPYMNVMRQLLLNQRPAAHITRIVDMIADDVRQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429442; 12663928 [H]