BacMap

Definition	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome.
Accession	NC_003197
Length	4,857,432

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The map label for this gene is yeaE [H]

Identifier: 16764639

GI number: 16764639

Start: 1366518

End: 1367375

Strand: Direct

Name: yeaE [H]

Synonym: STM1288

Alternate gene names: 16764639

Gene position: 1366518-1367375 (Clockwise)

Preceding gene: 16764638

Following gene: 16764642

Centisome position: 28.13

GC content: 55.13

Gene sequence:

>858_bases
ATGAAATCAGTGAAAAACGTAACGTTTTGCGGGCAGGTGACGCTTCCTGCCATCGGACAGGGAACATGGTATATGGGCGA
GCGCGCGGATCAACGTCAGCGCGAGGTTTCGGCGTTGCGCGCGGGGCTGGATTTGGGGTTACGCCTTATTGATACAGCGG
AAATGTATGCCGACGGCGGGGCGGAAAAGGTCGTGGGCGAGGCGTTAGCAGGGCGACGCGATGAGGCATTTCTGGTGTCA
AAAGTGTACCCGTGGAACGCTGGCGGCCAGAAGATAGTTGCCGCCTGTGAAGAAAGCCTGCGTCGTCTGAAAACAGATTA
TCTCGATCTCTATCTATTGCACTGGGCCGGAAGCTTTTCATTCGAAGAGACCGTTGAAGGTATGGAGCGGCTAATCGCGC
AGGGGAAAATTCGCCGTTGGGGAGTCTCTAATCTTGATTATGACGATATGCAGGCGCTGTGGCGCATCCCTGGGGGACAG
CAATGCGCGACAAATCAGGTGCTCTATCATCTGGCGTCACGTGGTATTGAGTATGATTTATTGCCGTGGTGTCAACAACA
GCGAATGCCAGTGATGGCCTATAGCCCGCTGGCGCAGGCTGGCCGGTTACGTAGCGGTTTACTGAATCATCCGGTGGTGA
ATGAAATTGCGCAAGCGCATAACGCTACGGCGGCGCAAATCTTACTGACGTGGGTGATTGCGCATCCGGGCGTGATGGCG
ATCCCGAAAGCCGGAAGTACAGAACACGTGAAGCAAAATGCGGCGGCGCTTGAGATCGCCTTGTCAGCAAACGAACTTGC
CTTACTGGACAACGCCTGGCCTGCGCCAAAAGGGAAAACCGCGTTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
GTGACAAGAAAATCGCCCCCTTGCGCGGTATGATGCCGGACATTACCGTAGGGTCTAAGAGTCCTGTATTGTTTTACCGT
CGAGTGACATTGAAAAGGAA

Downstream 100 bases:

>100_bases
CGCCGGATAAAATGTGTAAGCGCCGCCATCCGGCAGGTCATGCCTGATGGCGGCTGACGCCTTTCAGATCCTATAGTAAC
GCCGTTATCCATTCACTTTT

Product: aldehyde reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVS
KVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGSFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
IPKAGSTEHVKQNAAALEIALSANELALLDNAWPAPKGKTALDMV

Sequences:

>Translated_285_residues
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVS
KVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGSFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
IPKAGSTEHVKQNAAALEIALSANELALLDNAWPAPKGKTALDMV
>Mature_285_residues
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVS
KVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGSFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
IPKAGSTEHVKQNAAALEIALSANELALLDNAWPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=298, Percent_Identity=29.8657718120805, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=30.188679245283, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI93277124, Length=299, Percent_Identity=26.0869565217391, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI24497577, Length=299, Percent_Identity=28.4280936454849, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI5174391, Length=299, Percent_Identity=28.4280936454849, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI5174695, Length=287, Percent_Identity=27.1777003484321, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI300116273, Length=274, Percent_Identity=27.7372262773723, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI310109922, Length=273, Percent_Identity=27.8388278388278, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=28.6206896551724, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.2413793103448, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI310109920, Length=290, Percent_Identity=25.8620689655172, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI300116271, Length=266, Percent_Identity=26.6917293233083, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI45446745, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4503285, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5453543, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=26.8041237113402, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI223718702, Length=193, Percent_Identity=29.0155440414508, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788081, Length=281, Percent_Identity=78.2918149466192, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1786400, Length=259, Percent_Identity=30.1158301158301, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082198, Length=259, Percent_Identity=28.957528957529, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87081735, Length=306, Percent_Identity=27.1241830065359, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=27.1565495207668, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=25.4491017964072, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789199, Length=339, Percent_Identity=27.1386430678466, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787674, Length=257, Percent_Identity=24.5136186770428, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI48994888, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17552492, Length=270, Percent_Identity=31.4814814814815, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=29.3159609120521, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17561298, Length=279, Percent_Identity=30.4659498207885, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71998625, Length=279, Percent_Identity=29.3906810035842, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17566692, Length=297, Percent_Identity=27.6094276094276, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17537077, Length=301, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17537075, Length=301, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561300, Length=257, Percent_Identity=28.0155642023346, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538386, Length=277, Percent_Identity=29.2418772563177, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17550248, Length=295, Percent_Identity=24.7457627118644, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537079, Length=308, Percent_Identity=21.7532467532468, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320576, Length=303, Percent_Identity=26.4026402640264, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320079, Length=265, Percent_Identity=27.9245283018868, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322556, Length=270, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=310, Percent_Identity=23.5483870967742, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=315, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI221378297, Length=333, Percent_Identity=31.8318318318318, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24663317, Length=303, Percent_Identity=25.4125412541254, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24662789, Length=287, Percent_Identity=27.5261324041812, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45553081, Length=300, Percent_Identity=25.6666666666667, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24657054, Length=292, Percent_Identity=26.027397260274, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281366140, Length=256, Percent_Identity=26.171875, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI20129731, Length=282, Percent_Identity=26.5957446808511, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356425, Length=263, Percent_Identity=22.4334600760456, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24662781, Length=292, Percent_Identity=25.6849315068493, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 31328; Mature: 31328

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGG
CCCCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
AEKVVGEALAGRRDEAFLVSKVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGSFS
HHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQQCATNQVLYHLASRGIEYDL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
LPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
CCHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
IPKAGSTEHVKQNAAALEIALSANELALLDNAWPAPKGKTALDMV
ECCCCCHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGG
CCCCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
AEKVVGEALAGRRDEAFLVSKVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGSFS
HHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQQCATNQVLYHLASRGIEYDL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
LPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
CCHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
IPKAGSTEHVKQNAAALEIALSANELALLDNAWPAPKGKTALDMV
ECCCCCHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]