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The map label for this gene is aadA [H]

Identifier: 16764615

GI number: 16764615

Start: 1346596

End: 1347384

Strand: Direct

Name: aadA [H]

Synonym: STM1264

Alternate gene names: 16764615

Gene position: 1346596-1347384 (Clockwise)

Preceding gene: 308065967

Following gene: 16764616

Centisome position: 27.72

GC content: 54.5

Gene sequence:

>789_bases
ATGACGCTGTCCATACCGCCCTCGATTCAATGCCAAACGGAAGCGGCATGTCGCCTGATTACTCGTGTCACAGGCGATAC
GTTGCGTGCTATTCATTTATATGGTTCCGCTGTCGCGGGCGGTCTGAAGCCAAACAGCGACATTGATCTGCTGGTGACAA
TATGCCAGCCGCTGACGGAGGCCCAACGCGCAACGCTGATGCAGGAATTGCTGGCGCTTTCATCGCCGCCGGGGGCGTCG
GCAGAAAAACGCGCTCTGGAGGTCACTGTCGTGCTTTATTCGCAGCTGGTTCCCTGGTGTTTTCCACCTTCCAGGGAAAT
GCAATTTGGCGAGTGGCTAAGAGAGGACATTTGTCAGGGGATTTATGAACCAGCGCAGCAGGACTGGGACATGGTGTTAC
TGATAACCCAAATTCTGGAAACCAGTATACCGCTAAAGGGAGAACGCGCGGAACGGCTGTTCACGCCAGCCCCTGCGGCG
CAGTTGCTGAAGGCCTTGCGTTATCCCCTCGACCTTTGGCAATCCACGGCAGATGTGCAGGGAGATGAGTATCATATCGT
TTTAACCCTGGCGCGTATCTGGTATACCCTTTCTACCGGGAGATTTACCTCTAAGGATGCGGCGGCTGACTGGCTGTTAC
CTCAGTTGCCAGAAGATTATGCTGCCACGTTGCGTGCGGCGCAGCGTGAATATTTAGGTCTGGAGCAACAGGACTGGCAT
ATTTTGCTGCCTGCGGTCGTACGCTTTGTGGATTTTGCCAAAGCGCACATCCCCACGCAGTTCACATAA

Upstream 100 bases:

>100_bases
GCAATGTTAAAAGCTCGCTATGAATAGCGAGCTTTTTTTCTGCCGTTATGCCATATTTCTGGCAATCAATATAAAAAATA
CCTGCGCCCCCGGAGCGATG

Downstream 100 bases:

>100_bases
GATGCCCCAGGACGTCTGTCAGGTTGCGCAAACGGCGTTCCTCAACTACTACTTAATAGGTTCTCATCGCTGAAGTAAGC
AGATGATCTTATGCGGGCCA

Product: aminoglycoside resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVTICQPLTEAQRATLMQELLALSSPPGAS
AEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAA
QLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWH
ILLPAVVRFVDFAKAHIPTQFT

Sequences:

>Translated_262_residues
MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVTICQPLTEAQRATLMQELLALSSPPGAS
AEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAA
QLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWH
ILLPAVVRFVDFAKAHIPTQFT
>Mature_261_residues
TLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVTICQPLTEAQRATLMQELLALSSPPGASA
EKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAAQ
LLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWHI
LLPAVVRFVDFAKAHIPTQFT

Specific function: Mediates bacterial resistance to the antibiotics streptomycin and spectomycin [H]

COG id: COG1708

COG function: function code R; Predicted nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002934 [H]

Pfam domain/function: PF01909 NTP_transf_2 [H]

EC number: =2.7.7.47 [H]

Molecular weight: Translated: 29348; Mature: 29217

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVTICQPLTE
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQ
HHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCC
GDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWH
CCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCE
ILLPAVVRFVDFAKAHIPTQFT
EHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVTICQPLTE
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQ
HHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCC
GDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWH
CCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCE
ILLPAVVRFVDFAKAHIPTQFT
EHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3054482; 2997737; 2986186; 3037494; 2821509; 2823258; 2188588 [H]