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The map label for this gene is pncB [H]

Identifier: 16764364

GI number: 16764364

Start: 1096831

End: 1098033

Strand: Reverse

Name: pncB [H]

Synonym: STM1004

Alternate gene names: 16764364

Gene position: 1098033-1096831 (Counterclockwise)

Preceding gene: 16764365

Following gene: 16764361

Centisome position: 22.61

GC content: 54.45

Gene sequence:

>1203_bases
ATGACACAATTCGCTTCTCCTGTTCTGCACTCGTTGCTGGATACAGATGCTTATAAGTTGCATATGCAGCAAGCCGTTTT
TCACCACTACTATGATGTGCAGGTAGCGGCTGAGTTTCGTTGCCGTGGCGACGACCTGCTGGGTATTTATGCCGATGCTA
TTCGCGAGCAGGTGGACGCGATGCAGCACCTGCGCCTCCTGGAGGACGAGTTCCAGTGGCTCTCCGGCCTGCCCTTTTTT
AAACCGGATTATCTGAACTGGTTACGCGAGTTTCGCTATAACCCAGCTCAAGTCTGTGTCACCAACGATAACGGCAAGCT
GAATATTCGCTTAACCGGCCCGTGGCGTGAAGTCATTATGTGGGAAGTGCCGCTGCTGGCCGTGATCAGTGAGCTGGTTC
ATCACTACCGCTCGCCAAACGCGGGTGTTGATCAGGCGCTCGACGCGCTGGAAAGTAAGCTGGTTGATTTCACTGCGTTA
ACCGCCAATCTCGATATGTCCCGCTTCCACCTGATGGACTTCGGCACCCGCCGCCGTTTCTCTCGTGAAGTGCAGCAGGC
GATAGTTAAACGTCTCCAGCAGGAGTCATGGTTCGTCGGCACCAGCAACTATGATCTCGCGCGTCGCCTGGCGCTGACGC
CGATGGGCACTCAGGCGCACGAATGGTTCCAGGCGCATCAACAAATCAGTCCGGACCTGGCGACCAGCCAGCGTGCCGCG
TTGGCCGCCTGGCTTAACGAATATCCGGACCAGCTTGGTATCGCCTTGACAGATTGCATTACAATGGATGCGTTTTTACG
CGATTTCGGCATTGAATTCGCCAGCCGTTATCAGGGGTTACGCCACGACTCAGGAGACCCTGTCGCATGGGGCGAAAAGG
CGATTGCCCATTATGAAAAGCTGGGGATTGATCCGCTGACAAAAACGCTGGTCTTTTCAGATAACCTTGATCTGCCAAAG
GCGGTCGAGCTCTATCGCCATTTCGCCTCTCGCGTGCAGTTAAGCTTCGGCATCGGTACCCGCCTGACCTGCGATATCCC
TCAGGTAAAACCGCTCAATATCGTGATTAAGCTCGTGGAATGTAACGGAAAGCCGGTGGCTAAACTTTCCGACAGCCCCG
GTAAAACGATCTGTCATGATAAAGCGTTTGTGCGCGCGCTGCGTAAAGCGTTCGATCTCCCGCAGGTGCGTAAAGCAAGT
TAA

Upstream 100 bases:

>100_bases
GATCGGGGTTCAATAAATCGCTAAACAAGGTATACTCCAGCGGTTTTCTTAGTTGTTTATTGTACTAAACGCTCCCGTGA
GAGGACGCAACAGCGCACCT

Downstream 100 bases:

>100_bases
CCATGCCTGTGCGAAGCGCCCGGAAAGTGGGCGCTTTGTTACTCTTCTGACCATCTTACCTGTTCTGGCCGCGATGGTTA
CTCCTCTTTCCCTTCACTCT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLLEDEFQWLSGLPFF
KPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGPWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTAL
TANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAA
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPK
AVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS

Sequences:

>Translated_400_residues
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLLEDEFQWLSGLPFF
KPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGPWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTAL
TANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAA
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPK
AVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
>Mature_399_residues
TQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLLEDEFQWLSGLPFFK
PDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGPWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALT
ANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAAL
AAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPKA
VELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=400, Percent_Identity=91, Blast_Score=766, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324783, Length=419, Percent_Identity=34.3675417661098, Blast_Score=208, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45662; Mature: 45531

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHH
MQHLRLLEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGPWREVIM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCHHHHHH
WEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALTANLDMSRFHLMDFGTRRRF
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
SREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAA
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEK
HHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVE
HCCCHHHHHEEEECCCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHH
MQHLRLLEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGPWREVIM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCHHHHHH
WEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALTANLDMSRFHLMDFGTRRRF
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
SREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAA
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEK
HHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVE
HCCCHHHHHEEEECCCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA