Click here to switch to the map view.

The map label for this gene is sopD2

Identifier: 16764332

GI number: 16764332

Start: 1054061

End: 1055020

Strand: Direct

Name: sopD2

Synonym: STM0972

Alternate gene names: 16764332

Gene position: 1054061-1055020 (Clockwise)

Preceding gene: 16764329

Following gene: 16764336

Centisome position: 21.7

GC content: 33.33

Gene sequence:

>960_bases
ATGCCAGTTACGTTAAGTTTTGGTAATCGTCATAACTATGAAATTAATCATTCACGGCTAGCCCGTTTGATGAGTCCTGA
TAAAGAAGAAGCGCTATACATGGGGGTATGGGATAGATTTAAGGACTGCTTCAGAACACACAAAAAACAAGAGGTGCTGG
AGGTATTATATACACTCATCCATGGATGTGAACGTGAAAATCAAGCTGAACTTAATGTTGATATAACCGGCATGGAGAAG
ATACATGCCTTTACACAATTAAAAGAATATGCTAATCCATCTCAACAAGACCGCTTTGTTATGCGTTTTGATATGAATCA
GACACAAGTTTTATTTGAGATTGATGGCAAGGTTATTGATAAATGTAATTTGCATCGTCTCCTCAATGTTTCAGAAAACT
GTATTTTTAAAGTGATGGAAGAAGATGAAGAAGAGTTGTTTCTTAAAATATGTATTAAGTATGGAGAAAAAATTTCTCGC
TATCCAGAATTATTAGAAGGATTTGCTAATAAACTTAAAGATGCAGTTAATGAGGATGATGACGTTAAGGATGAAGTTTA
TAAGCTTATGCGATCTGGAGAAGATCGAAAAATGGAATGTGTTGAATGGAATGGTACTCTTACTGAAGAGGAGAAGAATA
AACTACGCTGTCTTCAAATGGGGTCTTTTAATATTACTACCCAATTTTTTAAAATAGGTTACTGGGAATTAGAGGGGGAA
GTCCTGTTTGATATGGTTCATCCAACACTTAGCTATCTGCTACAAGCATATAAACCGTCATTGTCATCTGATTTAATAGA
AACTAACACCATGCTGTTTTCTGATGTATTAAATAAGGATTATGATGATTATCAAAATAATAAAAGAGAAATTGATGCTA
TTCTAAGAAGAATATATAGATCACATAATAACACTTTATTTATAAGTGAAAAGTCGAGTTGTCGCAATATGCTTATATAA

Upstream 100 bases:

>100_bases
CCAGGCTGATTCAATCTCTTAAATAGAGTGTGGTTTTAATCAAAAAATGAGAGCAACGGATTGGATCTTGCTTTCGCGGT
AAATAATCAAGGGAGTTATT

Downstream 100 bases:

>100_bases
AAAGTCATTAAAAAGGCCCCACTGATATGGAGCCTTTTTTGTACGCTTTTTATGGCGTAATTTCAGTCAAACCCATTACA
TGGTCTGCGTGAAGGTACGA

Product: SopD-like protein

Products: NA

Alternate protein names: Salmonella outer protein D 2

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MPVTLSFGNRHNYEINHSRLARLMSPDKEEALYMGVWDRFKDCFRTHKKQEVLEVLYTLIHGCERENQAELNVDITGMEK
IHAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVIDKCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISR
YPELLEGFANKLKDAVNEDDDVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGE
VLFDMVHPTLSYLLQAYKPSLSSDLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISEKSSCRNMLI

Sequences:

>Translated_319_residues
MPVTLSFGNRHNYEINHSRLARLMSPDKEEALYMGVWDRFKDCFRTHKKQEVLEVLYTLIHGCERENQAELNVDITGMEK
IHAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVIDKCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISR
YPELLEGFANKLKDAVNEDDDVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGE
VLFDMVHPTLSYLLQAYKPSLSSDLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISEKSSCRNMLI
>Mature_318_residues
PVTLSFGNRHNYEINHSRLARLMSPDKEEALYMGVWDRFKDCFRTHKKQEVLEVLYTLIHGCERENQAELNVDITGMEKI
HAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVIDKCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISRY
PELLEGFANKLKDAVNEDDDVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGEV
LFDMVHPTLSYLLQAYKPSLSSDLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISEKSSCRNMLI

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to the formation of Salmonella-induced filaments (Sifs) in infected epithelial cells and to replication in macrophages

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell. Membrane-associated. Localizes to the Salmonella- containing vacuole (SCV) in infected cells and to late endocytic compartments in

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sopD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SOPD2_SALTY (Q8ZQC8)

Other databases:

- EMBL:   AE006468
- RefSeq:   NP_459947.1
- PRIDE:   Q8ZQC8
- GeneID:   1252490
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM0972
- NMPDR:   fig|99287.1.peg.937
- HOGENOM:   HBG671701
- OMA:   LKQYANP
- ProtClustDB:   PRK15380
- BioCyc:   STYP99287:STM0972-MONOMER
- GO:   GO:0016020
- GO:   GO:0009405
- InterPro:   IPR022747
- ProDom:   PD040905

Pfam domain/function: PF11047 SopD

EC number: NA

Molecular weight: Translated: 37783; Mature: 37651

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTLSFGNRHNYEINHSRLARLMSPDKEEALYMGVWDRFKDCFRTHKKQEVLEVLYTLI
CCEEEECCCCCCCEECHHHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGCERENQAELNVDITGMEKIHAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVID
HCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCHHHH
KCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISRYPELLEGFANKLKDAVNEDD
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGE
CHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEEHCCCCCCHHHHHHEEEEEEECCH
VLFDMVHPTLSYLLQAYKPSLSSDLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHH
SHNNTLFISEKSSCRNMLI
CCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
PVTLSFGNRHNYEINHSRLARLMSPDKEEALYMGVWDRFKDCFRTHKKQEVLEVLYTLI
CEEEECCCCCCCEECHHHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGCERENQAELNVDITGMEKIHAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVID
HCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCHHHH
KCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISRYPELLEGFANKLKDAVNEDD
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGE
CHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEEHCCCCCCHHHHHHEEEEEEECCH
VLFDMVHPTLSYLLQAYKPSLSSDLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHH
SHNNTLFISEKSSCRNMLI
CCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677609