| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
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The map label for this gene is mrcB [H]
Identifier: 16763580
GI number: 16763580
Start: 220923
End: 223445
Strand: Direct
Name: mrcB [H]
Synonym: STM0190
Alternate gene names: 16763580
Gene position: 220923-223445 (Clockwise)
Preceding gene: 16763579
Following gene: 16763581
Centisome position: 4.55
GC content: 56.76
Gene sequence:
>2523_bases ATGGCGGGGAATGACCGCGAGCCGATTGGACGTAAGGGGAAACCGTCACGTCCTGTGAAACAAAAGGTGAGCCGTCGTCG GCAGCATGACGACGATTATGATGATGACTATGAGGATGAAGAACCGATGCCGCGTAAAGGTAAGGGCAAAGGGCGTAAGC CTCGTGGCAAGCGCGGCTGGCTGTGGCTATTGCTAAAACTGTTTATCGTTTTTGTGGTGCTGTTCGCCATTTACGGCGTC TATCTGGATCAAAAAATCCGCAGCCGTATCGATGGCAAGGTCTGGCAGCTTCCGGCGGCGGTATATGGCCGGATGGTGAA CCTTGAGCCAGACATGCCTGTCAGCAAAAACGAGATGGTGAAATTGCTGGAAGCGACGCAGTATCGTCTGGTGACGAAGA TGACCCGTCCCGGCGAATTTACCGTGCAGGCCAATAGCATTGAGATGATCCGTCGTCCGTTTGACTTCCCGGACAGCAAA GAAGGGCAGGTGCGCGCGCGGCTGACGTTCAGTGACGGGCGTCTGGAAACCATCGTCAATCTGGATAACAACCGCCAGTT TGGCTTCTTCCGTCTCGATCCGCGGCTTATCACCATGCTTTCTTCGCCAAATGGCGAGCAGCGTTTATTCGTCCCGCGCA GCGGTTTCCCGGATCTGCTGGTCGATACGCTGTTGGCGACGGAAGACCGTCATTTCTATGAGCATGATGGCATTAGTCTT TACTCTATCGGGCGTGCGGTGCTGGCCAACCTGACGGCGGGACGCACGGTGCAGGGGGCCAGTACGCTGACCCAGCAGCT GGTGAAGAACCTGTTCCTCTCCAGCGAAAGATCATACTGGCGTAAAGCGAATGAAGCCTACATGGCGCTGATCATGGATG CCCGTTACAGTAAAGATCGTATTCTTGAGCTGTACATGAACGAGGTCTACCTCGGTCAAAGCGGGGACAATGAAATTCGC GGTTTTCCGCTGGCGAGCCTGTATTACTTTGGTCGTCCGGTAGAGGAACTGAGCCTCGATCAGCAGGCGTTACTGGTGGG GATGGTAAAAGGGGCGTCGATTTATAACCCGTGGCGTAACCCGAAACTGGCGTTGGAGCGTCGTAACCTGGTGTTACGCC TGTTACAGCAGCAGAAAATCATCGATCAGGAACTCTATGACATGCTGAGCGCGCGTCCGCTTGGCGTACAGCCGCGCGGC GGCGTTATTTCACCGCAGCCAGCGTTTATGCAGATGGTTCGTCAGGAACTGCAGGCGAAGCTGGGGGATAAAATTAAAGA TCTCTCCGGCGTGAAGATCTTCACCACCTTTGACTCCGTGGCGCAGGATGCCGCAGAAAAAGCCGTTGTCGAAGGTATTC CGGCGTTGAAGAAGCAGCGTAAATTGAGCGATCTGGAAACCGCGATGGTGGTGGTGGATCGCTTTAGCGGCGAGGTGCGC GCGATGGTTGGCGGGGCGGAGCCGCAGTATGCCGGCTATAACCGTGCCATGCAGGCGCGCCGTTCCATCGGGTCGCTGGC GAAACCGGCGACCTATCTGACCGCGTTAAGTCAGCCGAACTTATACCGTCTGAACACCTGGATTGCCGATGCGCCGATTT CTCTGCGCCAGCCGAATGGTCAGGTCTGGTCGCCGCAGAACGACGATCGTCGCTACAGCGAAAGCGGGAAAGTGATGCTG GTGGATGCGTTAACTCGCTCAATGAACGTACCGACGGTCAATCTGGGGATGGCGTTAGGTTTACCGGCGGTAACCGATAC CTGGACGAAGCTCGGCGTGCCGAAAGATCAGCTCAATCCGGTTCCGGCTATGCTGTTAGGAGCGCTGAACCTGACGCCGA TCGAAGTGGCGCAGGCGTTCCAGACTATCGCCAGCGGCGGAAATCGCGCGCCGTTATCAGCGCTGCGTTCAGTTATTGCG GAAGATGGTAAAGTGCTGTACCAAAGTTATCCGCAAGCTGAACGCGCCGTACCGGCACAGGCGGCTTACCTGACGCTCTG GACAATGCAGCAGGTCGTCCAGCGTGGTACGGGGCGTCAGCTTGGCGCGAAATATCCGGGTCTGCATCTGGCCGGTAAAA CCGGGACGACAAACAACAATGTCGATACCTGGTTTGCCGGTATCGACGGCAGCCAGGTGACTATCACCTGGGTAGGCCGT GATAACAACCAGCCGACGAAATTGTACGGCGCCAGCGGCGCGATGGCGATTTACCAGCGCTATCTGGCGAACCAGACGCC GACGCCTTTAGTTCTGACGCCGCCGGAAGATGTGGTGGATATGGGCGTTGATTACGACGGTAATTTTGTCTGTAGCGGCG GTATGCGCACTCTGCCGGTCTGGACGGACGATCCAAATACGCTGTGCCAGCAGGGCGAGATGATGCAGCAACAGCAGCAG CCGTCAGGCAATCCGTTCGATCAGTCGTCTCAGCCGCAGCAGCCTGCGCAGCAACAGCCGCCGAAAGAAGAGAAGAGCGA CGGCGTTGCCGGCTGGATTAAGGAGATGTTCGGCGGCAATTAA
Upstream 100 bases:
>100_bases CGCATCCGGCAAAAGAGTAAATTGAGAGATTTCTTCTTCTGTCGTCTGGCGGAAGAATAGAGAATCGGGCCTTTGCGCCT GTATGTTGCGGAGAAAAAGC
Downstream 100 bases:
>100_bases TCACGGTAATAGTGCCGGGTGGCGCTGTGCTTACCCGGTCTACACCGTTACGACCCCATTATGTGCGACGTAGGCCGAAT AAGACGCTTACGTCGCCATC
Product: penicillin-binding protein 1b
Products: NA
Alternate protein names: PBP-1b; PBP1b; Murein polymerase; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Peptidoglycan glycosyltransferase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 840; Mature: 839
Protein sequence:
>840_residues MAGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGV YLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSK EGQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIR GFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRG GVISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPQNDDRRYSESGKVML VDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIA EDGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPVWTDDPNTLCQQGEMMQQQQQ PSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN
Sequences:
>Translated_840_residues MAGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGV YLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSK EGQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIR GFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRG GVISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPQNDDRRYSESGKVML VDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIA EDGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPVWTDDPNTLCQQGEMMQQQQQ PSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN >Mature_839_residues AGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGVY LDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSKE GQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLY SIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRG FPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRGG VISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVRA MVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPQNDDRRYSESGKVMLV DALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAE DGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGRD NNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPVWTDDPNTLCQQGEMMQQQQQP SGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=847, Percent_Identity=90.318772136954, Blast_Score=1466, Evalue=0.0, Organism=Escherichia coli, GI87082258, Length=245, Percent_Identity=35.9183673469388, Blast_Score=154, Evalue=3e-38, Organism=Escherichia coli, GI1788867, Length=515, Percent_Identity=27.1844660194175, Blast_Score=126, Evalue=6e-30, Organism=Escherichia coli, GI1789601, Length=127, Percent_Identity=37.007874015748, Blast_Score=78, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011813 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 93869; Mature: 93737
Theoretical pI: Translated: 9.63; Mature: 9.63
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGW CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH LWLLLKLFIVFVVLFAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHCEEEECCCCCCCCHHHHH KLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFSDGRLETIVN HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEE LDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL CCCCCEEEEEEECHHHEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHCCCEEH YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDR HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHH ILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRN HHHHHHHHEEECCCCCCCCCCCCHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCC PKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRGGVISPQPAFMQMVRQELQAK CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH LGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR HCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNG EEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEEECCCCEEECCCC QVWSPQNDDRRYSESGKVMLVDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNP CCCCCCCCCCHHCCCCCEEEEEHHHHCCCCCEEECHHHHCCCCHHHHHHHCCCCHHHCCC VPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSYPQAERAVPAQ HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHCCCCH AAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEC DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPV CCCCCCEEECCCCHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCEEECCCCEEEEE WTDDPNTLCQQGEMMQQQQQPSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN EECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHCCCHHHHHHHHHCCC >Mature Secondary Structure AGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGW CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH LWLLLKLFIVFVVLFAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHCEEEECCCCCCCCHHHHH KLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFSDGRLETIVN HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEE LDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL CCCCCEEEEEEECHHHEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHCCCEEH YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDR HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHH ILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRN HHHHHHHHEEECCCCCCCCCCCCHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCC PKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRGGVISPQPAFMQMVRQELQAK CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH LGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR HCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNG EEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEEECCCCEEECCCC QVWSPQNDDRRYSESGKVMLVDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNP CCCCCCCCCCHHCCCCCEEEEEHHHHCCCCCEEECHHHHCCCCHHHHHHHCCCCHHHCCC VPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSYPQAERAVPAQ HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHCCCCH AAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEC DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPV CCCCCCEEECCCCHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCEEECCCCEEEEE WTDDPNTLCQQGEMMQQQQQPSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN EECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHCCCHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3882429; 8202364; 9278503; 3920658; 8645198; 9244263; 3330753; 1885547; 10037771; 10564478; 9841666 [H]