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The map label for this gene is fhuA [H]

Identifier: 16763581

GI number: 16763581

Start: 223738

End: 225927

Strand: Direct

Name: fhuA [H]

Synonym: STM0191

Alternate gene names: 16763581

Gene position: 223738-225927 (Clockwise)

Preceding gene: 16763580

Following gene: 16763582

Centisome position: 4.61

GC content: 51.05

Gene sequence:

>2190_bases
ATGGCGCGTCTTAAAACTGCTCAGCCAAACTCCTCACTGCGTAAAATCGCAGTTGTAGTAGCCACAGCGGTTAGCGGCAT
GTCTGTCTATGCACAGGCGGCGGTTCAACCGAAAGAAGAAACCATTACCGTAACCGCAGCGCCTGCCGCGCAGGAAAGTG
CCTGGGGACCGGCTCCGACCATCGCCGCGAAGCGTTCCGCCACCACCACCAAAACTGATACACCTATCGAAAAAACGCCA
CAGTCGGTTTCGGTGGTCACTAACGAAGAGATGCAGATGCATCAATTCCAGTCAGTAAAAGAAGCGTTGGGTTACACGCC
GGGTGTAACGGTAAGCAGCCGCGGCGCTTCCAATACCTATGACTTCGTGATTATCCGTGGCTTCTCTTCCGTCGGCCTGA
GCCAGAACAACTATCTGGATGGCCTGAAATTGCAGGGGAACTTCTACAACGATGCGGTTATTGATCCCTACATGCTTGAG
CGTGTTGAGTTGATGCGTGGCCCAACGTCCGTCCTCTACGGTAAGAGCAACCCGGGCGGTATCATTTCGATGGTTAGCAA
GCGGCCGACTACTGAGCCGCTGAAAGAAATTCAATTCAAAATGGGGACGGACAATTTGTTCCAGACCGGTTTTGATTTTA
GTGATTCCCTGGATGACAACGGTGAGTTCTCATATCGTCTGACGGGGCTGGCGCGTTCGACAAATGAGCAGCAAAAGAGT
TCTGAGTCGCAGCGCTATGCGATTGCGCCCTCTTTTACCTGGCGTCCTGATGAGAAAACGAATTTTACGTTCCTTTCTTA
TTTCCAGAACGAACCAGAGACCGGCTACTACGGCTGGCTGCCGAAAGAGGGAACGGTTGAACCGTTACCGAATGGTAAAC
GCTTGCCGACAGATTTCAATGAAGGGGCGTCAAACAACACCTATTCTCGTAACGAGAAAATGGTGGGATACAGTTTCGAG
CATGGCTTCAACGACACTTTTACCGTGCGCCAGAATTTACGTTTTGTCGAAATGAAAACCGCGCAAAAAAGCGTCTATGG
CACGGGGATTGCGGCGGACGGCCATACGCTTAACCGCGGTACTATCGTTGACAACGAGCGTTTACAGAATTTCAGCGTAG
ATACACAACTGGAAAGTAAATTCGCGACCGGCGATATTGATCATACGTTGCTGACGGGTGTCGATTTCATGCGTATGCGT
AATGATATTAACGCGACGTTTGGTAGCGCGCCGTCAATCGATCTCTATAACAATTACCATCCTGAATACTTTGCTTTCGG
CGGCGCTGAGCCGTACCAGATGAACGAAAGTAAACAAACAGGCCTCTATGTTCAGGATCAGGCGGAATGGAATAAGTGGG
TATTTACTCTCGGCGGCCGCTATGACTGGTCTAAACAAGCGACAACGGTGCGTCAGAATTCCACTACGCCGACAGAAGGA
TATATTGAACGTAATGACCACCAGTTCACCTGGCGCGGTGGCGTAAACTACGTATTCGATAATGGAATTTCACCTTACTT
CAGCTATAGCCAATCTTTCGAGCCAAGCGCCTTCGATTTGTGGAGCACCCCACGCGTTTCTTACAAGCCGTCAAAAGGCG
AGCAATATGAAGCAGGGGTGAAATATGTACCGAAAGACATGCCGGTTGTTGTTACGGGTGCCGTTTATCAGCTGACCAAA
ACCAATAACCTGACCGCCGATCCAACCAACCCATTAGCGCAGGTGCCGGCAGGCGAAATTCGTGCGCGAGGTGTAGAGCT
GGAAGCCAAAGCAGCATTGACGGCTAACATCAATATGACGGCGTCTTACACTTATACTGATGCTGAATACACGAAAGACA
CTAATCTGAAAGGGAATACGCCAGAGCAGGTGCCTGAACACATGGCGTCGTTGTGGGGCGATTACACCTTCAACGAAGGT
CCGTTGTCAGGTTTAACGCTGGGAACAGGCGGTCGTTTTATTGGTTCCAGTTACGGCGATCCGGCTAATAGCTTCAAGGT
AGGCAGCGCAGCGGTGATGGATGCGGTCGTCAAGTACGATCTGGCGCGTTTTGGTATGGCGGGCTCCAGCATTGCGGTTA
ACGTTAATAATCTGCTCGACCGCGAATACGTCGCCAGCTGCTTCCAGACCTACGGCTGTTTCTGGGGCGCAGAACGTCAG
GTCGTTGCAACGGCAACCTTCCGTTTCTAA

Upstream 100 bases:

>100_bases
GCGTATCGCTTGCCATTGCGACGATATTTCGCCTATCATGCTGCGGTTATAATAATAATTATCGTTTACGTTATCATTCA
CTTTCATCAGAGATATACCA

Downstream 100 bases:

>100_bases
TTTCTTTTTGGGCACGGCTTGCCGTGCCCGTTTTACAAGTTGGCTGCGATGCAGGAAAACCACATTCATTCCGATACCAC
CTTTGCGCTGCGAAGCGTCG

Product: ferrichrome outer membrane transporter

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MARLKTAQPNSSLRKIAVVVATAVSGMSVYAQAAVQPKEETITVTAAPAAQESAWGPAPTIAAKRSATTTKTDTPIEKTP
QSVSVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTYDFVIIRGFSSVGLSQNNYLDGLKLQGNFYNDAVIDPYMLE
RVELMRGPTSVLYGKSNPGGIISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDSLDDNGEFSYRLTGLARSTNEQQKS
SESQRYAIAPSFTWRPDEKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNEKMVGYSFE
HGFNDTFTVRQNLRFVEMKTAQKSVYGTGIAADGHTLNRGTIVDNERLQNFSVDTQLESKFATGDIDHTLLTGVDFMRMR
NDINATFGSAPSIDLYNNYHPEYFAFGGAEPYQMNESKQTGLYVQDQAEWNKWVFTLGGRYDWSKQATTVRQNSTTPTEG
YIERNDHQFTWRGGVNYVFDNGISPYFSYSQSFEPSAFDLWSTPRVSYKPSKGEQYEAGVKYVPKDMPVVVTGAVYQLTK
TNNLTADPTNPLAQVPAGEIRARGVELEAKAALTANINMTASYTYTDAEYTKDTNLKGNTPEQVPEHMASLWGDYTFNEG
PLSGLTLGTGGRFIGSSYGDPANSFKVGSAAVMDAVVKYDLARFGMAGSSIAVNVNNLLDREYVASCFQTYGCFWGAERQ
VVATATFRF

Sequences:

>Translated_729_residues
MARLKTAQPNSSLRKIAVVVATAVSGMSVYAQAAVQPKEETITVTAAPAAQESAWGPAPTIAAKRSATTTKTDTPIEKTP
QSVSVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTYDFVIIRGFSSVGLSQNNYLDGLKLQGNFYNDAVIDPYMLE
RVELMRGPTSVLYGKSNPGGIISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDSLDDNGEFSYRLTGLARSTNEQQKS
SESQRYAIAPSFTWRPDEKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNEKMVGYSFE
HGFNDTFTVRQNLRFVEMKTAQKSVYGTGIAADGHTLNRGTIVDNERLQNFSVDTQLESKFATGDIDHTLLTGVDFMRMR
NDINATFGSAPSIDLYNNYHPEYFAFGGAEPYQMNESKQTGLYVQDQAEWNKWVFTLGGRYDWSKQATTVRQNSTTPTEG
YIERNDHQFTWRGGVNYVFDNGISPYFSYSQSFEPSAFDLWSTPRVSYKPSKGEQYEAGVKYVPKDMPVVVTGAVYQLTK
TNNLTADPTNPLAQVPAGEIRARGVELEAKAALTANINMTASYTYTDAEYTKDTNLKGNTPEQVPEHMASLWGDYTFNEG
PLSGLTLGTGGRFIGSSYGDPANSFKVGSAAVMDAVVKYDLARFGMAGSSIAVNVNNLLDREYVASCFQTYGCFWGAERQ
VVATATFRF
>Mature_728_residues
ARLKTAQPNSSLRKIAVVVATAVSGMSVYAQAAVQPKEETITVTAAPAAQESAWGPAPTIAAKRSATTTKTDTPIEKTPQ
SVSVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTYDFVIIRGFSSVGLSQNNYLDGLKLQGNFYNDAVIDPYMLER
VELMRGPTSVLYGKSNPGGIISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDSLDDNGEFSYRLTGLARSTNEQQKSS
ESQRYAIAPSFTWRPDEKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNEKMVGYSFEH
GFNDTFTVRQNLRFVEMKTAQKSVYGTGIAADGHTLNRGTIVDNERLQNFSVDTQLESKFATGDIDHTLLTGVDFMRMRN
DINATFGSAPSIDLYNNYHPEYFAFGGAEPYQMNESKQTGLYVQDQAEWNKWVFTLGGRYDWSKQATTVRQNSTTPTEGY
IERNDHQFTWRGGVNYVFDNGISPYFSYSQSFEPSAFDLWSTPRVSYKPSKGEQYEAGVKYVPKDMPVVVTGAVYQLTKT
NNLTADPTNPLAQVPAGEIRARGVELEAKAALTANINMTASYTYTDAEYTKDTNLKGNTPEQVPEHMASLWGDYTFNEGP
LSGLTLGTGGRFIGSSYGDPANSFKVGSAAVMDAVVKYDLARFGMAGSSIAVNVNNLLDREYVASCFQTYGCFWGAERQV
VATATFRF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=754, Percent_Identity=73.7400530503979, Blast_Score=1107, Evalue=0.0,
Organism=Escherichia coli, GI1787024, Length=742, Percent_Identity=24.1239892183288, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787344, Length=786, Percent_Identity=22.5190839694656, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80627; Mature: 80496

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLKTAQPNSSLRKIAVVVATAVSGMSVYAQAAVQPKEETITVTAAPAAQESAWGPAPT
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
IAAKRSATTTKTDTPIEKTPQSVSVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTY
CEECCCCCCCCCCCCHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCE
DFVIIRGFSSVGLSQNNYLDGLKLQGNFYNDAVIDPYMLERVELMRGPTSVLYGKSNPGG
EEEEEECCHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
IISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDSLDDNGEFSYRLTGLARSTNEQQKS
EEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEEEEEEHHCCCHHHHH
SESQRYAIAPSFTWRPDEKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
CCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
EGASNNTYSRNEKMVGYSFEHGFNDTFTVRQNLRFVEMKTAQKSVYGTGIAADGHTLNRG
CCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEEEHHHHHHCCCCEECCCCCCCCC
TIVDNERLQNFSVDTQLESKFATGDIDHTLLTGVDFMRMRNDINATFGSAPSIDLYNNYH
EEECCHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCC
PEYFAFGGAEPYQMNESKQTGLYVQDQAEWNKWVFTLGGRYDWSKQATTVRQNSTTPTEG
CCEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCC
YIERNDHQFTWRGGVNYVFDNGISPYFSYSQSFEPSAFDLWSTPRVSYKPSKGEQYEAGV
CEECCCCEEEEECCCEEEECCCCCHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCC
KYVPKDMPVVVTGAVYQLTKTNNLTADPTNPLAQVPAGEIRARGVELEAKAALTANINMT
EECCCCCCEEEECEEEEEEECCCCCCCCCCCHHHCCCCHHHCCCEEEEEEEEEEEEEEEE
ASYTYTDAEYTKDTNLKGNTPEQVPEHMASLWGDYTFNEGPLSGLTLGTGGRFIGSSYGD
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
PANSFKVGSAAVMDAVVKYDLARFGMAGSSIAVNVNNLLDREYVASCFQTYGCFWGAERQ
CCCCEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCE
VVATATFRF
EEEEEEECC
>Mature Secondary Structure 
ARLKTAQPNSSLRKIAVVVATAVSGMSVYAQAAVQPKEETITVTAAPAAQESAWGPAPT
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
IAAKRSATTTKTDTPIEKTPQSVSVVTNEEMQMHQFQSVKEALGYTPGVTVSSRGASNTY
CEECCCCCCCCCCCCHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCE
DFVIIRGFSSVGLSQNNYLDGLKLQGNFYNDAVIDPYMLERVELMRGPTSVLYGKSNPGG
EEEEEECCHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
IISMVSKRPTTEPLKEIQFKMGTDNLFQTGFDFSDSLDDNGEFSYRLTGLARSTNEQQKS
EEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEEEEEEHHCCCHHHHH
SESQRYAIAPSFTWRPDEKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
CCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
EGASNNTYSRNEKMVGYSFEHGFNDTFTVRQNLRFVEMKTAQKSVYGTGIAADGHTLNRG
CCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEEEHHHHHHCCCCEECCCCCCCCC
TIVDNERLQNFSVDTQLESKFATGDIDHTLLTGVDFMRMRNDINATFGSAPSIDLYNNYH
EEECCHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCC
PEYFAFGGAEPYQMNESKQTGLYVQDQAEWNKWVFTLGGRYDWSKQATTVRQNSTTPTEG
CCEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCC
YIERNDHQFTWRGGVNYVFDNGISPYFSYSQSFEPSAFDLWSTPRVSYKPSKGEQYEAGV
CEECCCCEEEEECCCEEEECCCCCHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCC
KYVPKDMPVVVTGAVYQLTKTNNLTADPTNPLAQVPAGEIRARGVELEAKAALTANINMT
EECCCCCCEEEECEEEEEEECCCCCCCCCCCHHHCCCCHHHCCCEEEEEEEEEEEEEEEE
ASYTYTDAEYTKDTNLKGNTPEQVPEHMASLWGDYTFNEGPLSGLTLGTGGRFIGSSYGD
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
PANSFKVGSAAVMDAVVKYDLARFGMAGSSIAVNVNNLLDREYVASCFQTYGCFWGAERQ
CCCCEECCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCE
VVATATFRF
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]