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The map label for this gene is panC [H]

Identifier: 218930419

GI number: 218930419

Start: 3800086

End: 3800940

Strand: Direct

Name: panC [H]

Synonym: YPO3402

Alternate gene names: 218930419

Gene position: 3800086-3800940 (Clockwise)

Preceding gene: 218930418

Following gene: 218930420

Centisome position: 81.66

GC content: 53.1

Gene sequence:

>855_bases
ATGCTGATTATTGAGACATTGCCATTGCTACGTCAACAGATCCGCCGTTGGCGTCAGGAAGGCAAACGAATTGCCTTAGT
ACCCACCATGGGTAACCTGCACGAAGGGCATATGACGCTGGTGGATGAAGCAAAAACCCGCGCTGACGTGGTCGTGGTGA
CTATTTTTGTTAATCCGCTGCAATTTGAACGGCCAGATGACTTAGCCCATTACCCGCGCACCTTACAGGAAGATTGCGAG
AAACTGACCCGCCACGGTGCAGATCTGGTGTTCGCACCGGCCGCAGCCGATATCTACCCTGCGGGGCTGGAAAAGCAAAC
GTATGTTGATGTTCCTGCCCTATCGACCATTTTAGAAGGGGCCAGCCGCCCTGGTCATTTCCGCGGTGTTTCAACCATCG
TCAGCAAGCTGTTTAATCTGATCCAGCCAGATGTCGCCTGTTTCGGCGAAAAAGATTACCAGCAGCTCGCCTTGATCCGC
AAAATGGTGGCGGATATGGGTTATGACATCAACATTGTTGGGGTACCAACGGTGCGCGCGAAAGATGGTTTGGCGCTGAG
TTCCCGTAACGGCTATCTGACGGAAGAAGAACGTCAGATTGCGCCACAGCTCAGTAAGATCATGTGGGCGCTGGCAGAGA
AAATGGCCTTAGGCGAACGGCAGATTGACGCACTGTTGGAAGAGGCGGCAGCGCAGCTACTCCGTGTAGGCTTTACGCCC
GATGAATTGTTTATCCGCGATGCCGAGACCTTACAGCCACTGACTGTCGATAGCCAGCAAGCGGTGATTTTGATGGCCGC
CTGGTTGGGTAAAGCTCGTCTGATTGATAACCAACTGGTTGATTTGCGCCACTGA

Upstream 100 bases:

>100_bases
TACATTCCAGTAACTGAGCCACTAATATTTCTTCTAAAATAGGGAGTTTTCAAAATAGGATCCTCCTAAAATAGATCGTT
CCTAAAACAGGAGAAAGGGA

Downstream 100 bases:

>100_bases
TATTTTACCGATCAGGCGGTTGCTCATTCCCCTCAAGCCGCGAGTTGGCCCAAAATCAACCAGGAACGCCAAGGTAAAAG
TCACTATCAACAGCATTCCC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCE
KLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIR
KMVADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTP
DELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH

Sequences:

>Translated_284_residues
MLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCE
KLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIR
KMVADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTP
DELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH
>Mature_284_residues
MLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCE
KLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIR
KMVADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTP
DELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=71.9858156028369, Blast_Score=428, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322046, Length=302, Percent_Identity=36.4238410596026, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31772; Mature: 31772

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPL
CEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEEECCC
QFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEG
CCCCCCHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECHHHHHHHHHC
ASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMVADMGYDINIVGVPTVRA
CCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEC
KDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTP
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
DELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH
HHHEEECHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPL
CEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEEECCC
QFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEG
CCCCCCHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECHHHHHHHHHC
ASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMVADMGYDINIVGVPTVRA
CCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEC
KDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTP
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
DELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH
HHHEEECHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA