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The map label for this gene is mdtI [H]

Identifier: 218929176

GI number: 218929176

Start: 2349530

End: 2349826

Strand: Direct

Name: mdtI [H]

Synonym: YPO2069

Alternate gene names: 218929176

Gene position: 2349530-2349826 (Clockwise)

Preceding gene: 218929175

Following gene: 218929178

Centisome position: 50.49

GC content: 48.15

Gene sequence:

>297_bases
TTGATCTTGGCCGTTATGCTGGAAATCGTCGCTAATATCTTGCTGAAAATGTCAGATGGCTTTCGCCGAAAATGGTTGGG
GATATTGTCCCTGTTGTCAGTATTAGGCGCATTCAGTGCATTGGCGCAAGCAGTGAAGGGGATTGAGCTGTCGGTAGCTT
ATGCCTTGTGGGGCGGTTTTGGTATTGCGGCCACTGTTGCGGCGGGCTGGATTCTGTTTAATCAACGGTTGAACTACAAA
GGTTGGATTGGTTTGATCTTACTGCTGGCGGGCATGGTGATGATTAAGTTGTCATAG

Upstream 100 bases:

>100_bases
GTACAGGAATTAAAAACACAGACTACCGGCCATCATAAGGGTGTTGCTGTTGAGTCAGGTGAGCATCATGCAGCAGCTTG
AGTTTTACCCTATAGCTTTC

Downstream 100 bases:

>100_bases
CGGGGCCAGAGGCAGTAAGCGGAGGGTAGCCTGGCGGCTACTCTCCTTTGTTTTTGTGGCTTAGTGACATTTATCGTTTA
GCAACATCTATCACTCAACT

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIAATVAAGWILFNQRLNYK
GWIGLILLLAGMVMIKLS

Sequences:

>Translated_98_residues
MILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIAATVAAGWILFNQRLNYK
GWIGLILLLAGMVMIKLS
>Mature_98_residues
MILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIAATVAAGWILFNQRLNYK
GWIGLILLLAGMVMIKLS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=96, Percent_Identity=79.1666666666667, Blast_Score=136, Evalue=3e-34,
Organism=Escherichia coli, GI1786755, Length=94, Percent_Identity=35.1063829787234, Blast_Score=65, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10566; Mature: 10566

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGF
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
GIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGF
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
GIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA