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The map label for this gene is asnC [H]

Identifier: 218928560

GI number: 218928560

Start: 1600525

End: 1601925

Strand: Reverse

Name: asnC [H]

Synonym: YPO1412

Alternate gene names: 218928560

Gene position: 1601925-1600525 (Counterclockwise)

Preceding gene: 218928561

Following gene: 218928559

Centisome position: 34.42

GC content: 49.89

Gene sequence:

>1401_bases
ATGAGCGTAGTGCCTGTAGTCGACGTACTGCAAGGCCGCGCCGCGGTTGGCAGTGAAGTCACCGTGCGCGGTTGGGTGCG
TACCCGGAGAGATTCTAAAGCGGGTATCTCCTTCGTTGCCGTTTATGACGGTTCCTGCTTTGACCCGTTACAGGCCGTCG
TGAATAATACTTTGCCGAATTATCAGGATGAAGTACTGCATCTGACCACCGGTTGTTCCGTTGAAGTCACCGGTACCGTG
GTCGCATCACCGGGTGAAGGCCAAAGTTTTGAAATTCAAGCAACCGCCATCAACGTAGTAGGCTGGGTTGATGATCCGGA
TACCTACCCGATGGCCGCAAAACGTCACAGCATTGAATATTTGCGTGAAGTGGCTCACTTACGCCCGCGTACTAACCTGA
TTGGTGCCGTTGCCCGTGTTCGCCACACGTTGGCACAAGCAATCCACCGCTTCTTCGACGAAAATGGGTATTTCTGGGTT
TCTACACCACTGATCACCGCCTCTGATACTGAAGGCGCAGGTGAGATGTTCCGTGTTTCAACTTTAGATCTGGAAAACTT
GCCACGCACGGATACCGGTGCTGTCGATTTCAGCGAAGACTTCTTCGGTAAAGAAGCGTTCCTGACCGTATCGGGTCAGC
TAAACGGTGAAACCTACGCCTGTGCATTATCAAAGGTTTACACCTTTGGCCCAACCTTCCGGGCTGAAAACTCCAATACC
AGCCGCCATTTGGCTGAATTCTGGATGGTTGAGCCGGAAGTGGCCTTCGCTTCTCTGGATGATGTCGCCGGTTTGGCTGA
GAAAATGTTGAAATACGTTTTCCAGGCGGTCTTGAATGAACGTGCTGATGACATGAAGTTCTTTGCCGAACGTGTCGATA
AAGACGCGGTTGACCGCCTGCAACGTTTCGTCACCTCTGATTTTGCTCAGGTTGACTACACTGATGCCATTGAGATCTTG
CTGGCATCCGGTCAGAAGTTTGAGAATGATGTTTCATGGGGTATTGATTTGTCCTCTGAACATGAGCGTTATCTGGCTGA
GAAACACTTTAAAGCGCCGGTGGTGGTTAAAAACTATCCGAAAGATATTAAAGCCTTCTATATGCGAATGAATGAAGATG
GCAAAACCGTTGCGGCGATGGATGTTTTAGCGCCGGGTATTGGTGAAATCATCGGTGGTTCACAACGTGAAGAGCGTTTA
GATGTCTTGGATGCGCGTTTAGCCGAAATGGGCCTGAATAAAGAAGATTATTGGTGGTATCGTGATCTGCGTCGCTACGG
CACTGTACCGCATTCAGGTTTTGGCCTCGGATTTGAGCGTTTAATCTCATATGTCACTGGGGTTCAAAACGTTCGGGACG
TTATTCCGTTCCCACGCACACCGAGAAATGCCAGTTTCTAA

Upstream 100 bases:

>100_bases
GAACTGACTCAAGTCAGAGATTCAGATGAGTGAGAGCCGCTAACACACTGCAACTTCAAGGAAGCAGGGTTTATATCCAA
ACCATTAAAGAGAGAAATCT

Downstream 100 bases:

>100_bases
GTTTATTATTTAGAAAATAACGTCAATTTGTACAAATAAAAGCCAGCTCTGCTGGCTTTTATCATTTTTTAAAATTCGAT
CTAAGTCACAAAGTTCCCTT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPNYQDEVLHLTTGCSVEVTGTV
VASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRLQRFVTSDFAQVDYTDAIEIL
LASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARLAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF

Sequences:

>Translated_466_residues
MSVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPNYQDEVLHLTTGCSVEVTGTV
VASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRLQRFVTSDFAQVDYTDAIEIL
LASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARLAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF
>Mature_465_residues
SVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPNYQDEVLHLTTGCSVEVTGTVV
ASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWVS
TPLITASDTEGAGEMFRVSTLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRLQRFVTSDFAQVDYTDAIEILL
ASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDARLAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=43.6285097192225, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI4758762, Length=452, Percent_Identity=28.9823008849558, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI45439306, Length=349, Percent_Identity=28.3667621776504, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=87.3390557939914, Blast_Score=863, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789256, Length=342, Percent_Identity=23.6842105263158, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=454, Percent_Identity=30.8370044052863, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=30.2325581395349, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17551876, Length=340, Percent_Identity=27.0588235294118, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=470, Percent_Identity=35.9574468085106, Blast_Score=290, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321807, Length=459, Percent_Identity=31.5904139433551, Blast_Score=203, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6323011, Length=348, Percent_Identity=26.7241379310345, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922416, Length=453, Percent_Identity=35.0993377483444, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI19921528, Length=481, Percent_Identity=29.3139293139293, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI17136276, Length=340, Percent_Identity=26.4705882352941, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52074; Mature: 51943

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPN
CCCCCHHHHHCCCHHCCCCEEEEHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCC
YQDEVLHLTTGCSVEVTGTVVASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEY
CCCCEEEEECCCEEEEEEEEEECCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNT
EECCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHH
QRFVTSDFAQVDYTDAIEILLASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARLAEMGLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPN
CCCCHHHHHCCCHHCCCCEEEEHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCC
YQDEVLHLTTGCSVEVTGTVVASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEY
CCCCEEEEECCCEEEEEEEEEECCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNT
EECCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHH
QRFVTSDFAQVDYTDAIEILLASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARLAEMGLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA