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The map label for this gene is aspC [H]

Identifier: 218928558

GI number: 218928558

Start: 1597698

End: 1598888

Strand: Reverse

Name: aspC [H]

Synonym: YPO1410

Alternate gene names: 218928558

Gene position: 1598888-1597698 (Counterclockwise)

Preceding gene: 218928559

Following gene: 218928545

Centisome position: 34.36

GC content: 49.45

Gene sequence:

>1191_bases
ATGTTTGAAAAAATTACTGCTGCACCTGCGGATCCTATTTTAGGTTTGACCGATATCTTCCGCGCGGATGACCGCGCTCA
TAAAATCAATCTGGGGATCGGTGTCTACAAAGACGAAACCGGTAAAACCCCAGTGCTGACCAGCGTGAAGAAAGCTGAGC
AGTATTTACTGGAAAATGAAGCTACCAAAAATTATCTGGGTATTGACGGCCTGCCTGTTTTTGCCAGTTGCACCCAAGAA
CTGCTGTTCGGTGCTAATAGTGCAATTATTGCGGATAAACGTGCTCGTACCGCTCAAACGCCAGGTGGTACCGGTGGTTT
GCGCATTGCCGCTGATTTTATCGCCCATCAGACCAGCGCTAAACGTGTCTGGGTCAGTAACCCAAGCTGGCCAAACCATA
AAAACGTCTTCGAAGCCGCAGGGCTGGAAGTGGTGGAGTACGCTTATTATGATGCTGCTAACCATGCATTGGACTTCGAT
GGCTTGTTAAATAGCCTGTCAGAAGCTCAGGCGGGTGATGTGGTGTTGTTCCACGGCTGCTGCCATAACCCAACGGGTAT
CGACCCAACAGAAACTCAGTGGAGCCAACTGGCGGAGTTATCGGTTGCTAAAGGCTGGTTGCCACTGTTTGATTTCGCTT
ATCAAGGCTTTGCCAACGGTTTGGAAGAAGATGCTCAGGGCCTGCGTATTTTCGCGGCAACACATCAAGAGTTGATCGTT
TGCAGCTCTTATTCGAAAAACTTTGGTTTGTACAATGAACGTGTTGGGGCTTGTACCCTTGTCGCCGCCGACAGTAACGT
TGCCGATACCGCATTCAGCCAAGTTAAAGCGGTTATCCGAGCCAACTACTCTAACCCACCGGCACATGGTGCATCAGTCG
TTGCCACTATTCTGAGTAATGCCGCACTACGGGCGATTTGGGAACAAGAACTGACCGATATGCGTCAGCGCATCCAACGT
ATGCGTCAGTTGTTTGTTAATACCTTGCAGGAAAAAGGCGCTCAACAAGATTTTAGCTTTATCATTAACCAGAATGGGAT
GTTCTCGTTCAGTGGTCTGACCAAAGAACAAGTGCTGCGCCTGCGTGATGAGTTCGCCGTCTATGCGGTAAATTCTGGCC
GGGTTAACGTGGCGGGGATGACACCAGACAATATGGCGCCGTTATGTGAAGCTATCGTTGCGGTGCTCTAA

Upstream 100 bases:

>100_bases
CAGATTCATTTCTTTTTATCGCAAACGGTTGGCAAAGACCGCAACTGGCGTTACCCTGAAGGCTCTGTTTGCTTAACGCT
AAGCCATGGAAGCCTCTGAC

Downstream 100 bases:

>100_bases
CTCAGTATCCGTTATCATCCCTTGACTGACCATAAAAGGATGGCCCAAGCCATCCTTCAGACTGCTGACAAACCCCGATG
ACGCGATCTTGAACGGTGAG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFEKITAAPADPILGLTDIFRADDRAHKINLGIGVYKDETGKTPVLTSVKKAEQYLLENEATKNYLGIDGLPVFASCTQE
LLFGANSAIIADKRARTAQTPGGTGGLRIAADFIAHQTSAKRVWVSNPSWPNHKNVFEAAGLEVVEYAYYDAANHALDFD
GLLNSLSEAQAGDVVLFHGCCHNPTGIDPTETQWSQLAELSVAKGWLPLFDFAYQGFANGLEEDAQGLRIFAATHQELIV
CSSYSKNFGLYNERVGACTLVAADSNVADTAFSQVKAVIRANYSNPPAHGASVVATILSNAALRAIWEQELTDMRQRIQR
MRQLFVNTLQEKGAQQDFSFIINQNGMFSFSGLTKEQVLRLRDEFAVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL

Sequences:

>Translated_396_residues
MFEKITAAPADPILGLTDIFRADDRAHKINLGIGVYKDETGKTPVLTSVKKAEQYLLENEATKNYLGIDGLPVFASCTQE
LLFGANSAIIADKRARTAQTPGGTGGLRIAADFIAHQTSAKRVWVSNPSWPNHKNVFEAAGLEVVEYAYYDAANHALDFD
GLLNSLSEAQAGDVVLFHGCCHNPTGIDPTETQWSQLAELSVAKGWLPLFDFAYQGFANGLEEDAQGLRIFAATHQELIV
CSSYSKNFGLYNERVGACTLVAADSNVADTAFSQVKAVIRANYSNPPAHGASVVATILSNAALRAIWEQELTDMRQRIQR
MRQLFVNTLQEKGAQQDFSFIINQNGMFSFSGLTKEQVLRLRDEFAVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL
>Mature_396_residues
MFEKITAAPADPILGLTDIFRADDRAHKINLGIGVYKDETGKTPVLTSVKKAEQYLLENEATKNYLGIDGLPVFASCTQE
LLFGANSAIIADKRARTAQTPGGTGGLRIAADFIAHQTSAKRVWVSNPSWPNHKNVFEAAGLEVVEYAYYDAANHALDFD
GLLNSLSEAQAGDVVLFHGCCHNPTGIDPTETQWSQLAELSVAKGWLPLFDFAYQGFANGLEEDAQGLRIFAATHQELIV
CSSYSKNFGLYNERVGACTLVAADSNVADTAFSQVKAVIRANYSNPPAHGASVVATILSNAALRAIWEQELTDMRQRIQR
MRQLFVNTLQEKGAQQDFSFIINQNGMFSFSGLTKEQVLRLRDEFAVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=393, Percent_Identity=41.9847328244275, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI4504067, Length=400, Percent_Identity=40.75, Blast_Score=294, Evalue=1e-79,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=28.7206266318538, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=86.1111111111111, Blast_Score=716, Evalue=0.0,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=42.3173803526448, Blast_Score=339, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI71981858, Length=392, Percent_Identity=40.5612244897959, Blast_Score=327, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI25147133, Length=392, Percent_Identity=39.5408163265306, Blast_Score=321, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=38.7341772151899, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17569537, Length=393, Percent_Identity=31.0432569974555, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI25147136, Length=220, Percent_Identity=37.2727272727273, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=34.2205323193916, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=39.4088669950739, Blast_Score=304, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6322743, Length=432, Percent_Identity=31.712962962963, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=42.6767676767677, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=42.6767676767677, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=43.0769230769231, Blast_Score=320, Evalue=7e-88,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=38.8471177944862, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=38.8471177944862, Blast_Score=302, Evalue=3e-82,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43119; Mature: 43119

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKITAAPADPILGLTDIFRADDRAHKINLGIGVYKDETGKTPVLTSVKKAEQYLLENE
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCC
ATKNYLGIDGLPVFASCTQELLFGANSAIIADKRARTAQTPGGTGGLRIAADFIAHQTSA
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCC
KRVWVSNPSWPNHKNVFEAAGLEVVEYAYYDAANHALDFDGLLNSLSEAQAGDVVLFHGC
CEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECC
CHNPTGIDPTETQWSQLAELSVAKGWLPLFDFAYQGFANGLEEDAQGLRIFAATHQELIV
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCEEEEEECCCEEEE
CSSYSKNFGLYNERVGACTLVAADSNVADTAFSQVKAVIRANYSNPPAHGASVVATILSN
EECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGAQQDFSFIINQNGMFSFSGLTKEQVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCHHHHHH
LRDEFAVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL
HHHCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MFEKITAAPADPILGLTDIFRADDRAHKINLGIGVYKDETGKTPVLTSVKKAEQYLLENE
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCC
ATKNYLGIDGLPVFASCTQELLFGANSAIIADKRARTAQTPGGTGGLRIAADFIAHQTSA
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCC
KRVWVSNPSWPNHKNVFEAAGLEVVEYAYYDAANHALDFDGLLNSLSEAQAGDVVLFHGC
CEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECC
CHNPTGIDPTETQWSQLAELSVAKGWLPLFDFAYQGFANGLEEDAQGLRIFAATHQELIV
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCEEEEEECCCEEEE
CSSYSKNFGLYNERVGACTLVAADSNVADTAFSQVKAVIRANYSNPPAHGASVVATILSN
EECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGAQQDFSFIINQNGMFSFSGLTKEQVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCHHHHHH
LRDEFAVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL
HHHCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]