BacMap

Definition	Yersinia pestis CO92 chromosome, complete genome.
Accession	NC_003143
Length	4,653,728

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The map label for this gene is fabG [H]

Identifier: 218928438

GI number: 218928438

Start: 1445162

End: 1445977

Strand: Reverse

Name: fabG [H]

Synonym: YPO1287

Alternate gene names: 218928438

Gene position: 1445977-1445162 (Counterclockwise)

Preceding gene: 218928439

Following gene: 218928436

Centisome position: 31.07

GC content: 58.7

Gene sequence:

>816_bases
ATGAATGACCACAAAAAGCGGCCTGATCTCGAAAAGCGGCCTGATCTCGAAAAACAATCTTATCCCGAAAAACAGAGCCT
GTCTGGGAAGCGGGCGCTGGTGACTGGTGCAGGTCAGGGGATCGGGGCGGCAATCGCTGAAGGGCTGGCGGCAACCGGTG
CGGAAGTGATCTGCACCGATATTTCACGTGAACGCGCCGCAGCAACCGCGCAAGCACTGAACGCCAAGGGCTACAACGTG
CGGGCCGAGGGACTGGACGTTACCGACAGCGCGGCTATTGACGCTCTGGCCGCCGCGTTACCGCCATTGGACGTGCTGGT
CTGCAATGCCGGGATCGTGACCCATACCCCGGCTGAAGAGATGACCGACGCGGACTGGGATAAGGTCATCGCCGTCAACT
TGACTGGCGTGTTTCGCACCTGTCGTGGCTTTGGCCGCCGGATGCTTGAAGCGGGGCGCGGCTCGATCATCAATATCGGT
TCGATATCGGGCCAAATCGTTAATGTGCCGCAGCCTCAGTGCCACTACAATGCATCGAAGGCGGGAGTACACCATTTGAC
CAAATCACTGGCGGTGGAGTGGGCCACACGTGGCGTTCGCGTCAATGCCGTCGCCCCCACCTATATAGAAACACCACTGA
TACAAGGGTTGACCAGCCAGCCGGGGCGGGTATCGCGATGGCTCGATATGACCCCCATGGGGCGGTTAGGCAGCCCCCAT
GAAATTGCTTCTGTGGTGCAGTTTTTGGCTTCGGAGGCCTCCAGCTTGCTGACAGGTTCAATCATTACTGCCGATGCGGG
ATATACCAGCATCTGA

Upstream 100 bases:

>100_bases
GATGCGTCGGTCAAAAAACTGCAACAACTGGCTTCTGAAGAGGCCCTACGGGGACTGCGCGGTGAGCCACTGCGCTGCCC
ACTGACTTAAGGAGAAGAGG

Downstream 100 bases:

>100_bases
GGGCGGTCAGGAGAAGCAGAGGAACACGTACTGGCAGCGGAGAGAATCAGCCGATCGTAAAAGCGCATTTAAGGCGCAGT
CACCGCTTCCAGCGCAATCA

Product: putative short chain oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MNDHKKRPDLEKRPDLEKQSYPEKQSLSGKRALVTGAGQGIGAAIAEGLAATGAEVICTDISRERAAATAQALNAKGYNV
RAEGLDVTDSAAIDALAAALPPLDVLVCNAGIVTHTPAEEMTDADWDKVIAVNLTGVFRTCRGFGRRMLEAGRGSIINIG
SISGQIVNVPQPQCHYNASKAGVHHLTKSLAVEWATRGVRVNAVAPTYIETPLIQGLTSQPGRVSRWLDMTPMGRLGSPH
EIASVVQFLASEASSLLTGSIITADAGYTSI

Sequences:

>Translated_271_residues
MNDHKKRPDLEKRPDLEKQSYPEKQSLSGKRALVTGAGQGIGAAIAEGLAATGAEVICTDISRERAAATAQALNAKGYNV
RAEGLDVTDSAAIDALAAALPPLDVLVCNAGIVTHTPAEEMTDADWDKVIAVNLTGVFRTCRGFGRRMLEAGRGSIINIG
SISGQIVNVPQPQCHYNASKAGVHHLTKSLAVEWATRGVRVNAVAPTYIETPLIQGLTSQPGRVSRWLDMTPMGRLGSPH
EIASVVQFLASEASSLLTGSIITADAGYTSI
>Mature_271_residues
MNDHKKRPDLEKRPDLEKQSYPEKQSLSGKRALVTGAGQGIGAAIAEGLAATGAEVICTDISRERAAATAQALNAKGYNV
RAEGLDVTDSAAIDALAAALPPLDVLVCNAGIVTHTPAEEMTDADWDKVIAVNLTGVFRTCRGFGRRMLEAGRGSIINIG
SISGQIVNVPQPQCHYNASKAGVHHLTKSLAVEWATRGVRVNAVAPTYIETPLIQGLTSQPGRVSRWLDMTPMGRLGSPH
EIASVVQFLASEASSLLTGSIITADAGYTSI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=40.9638554216867, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=32.9545454545455, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=33.6032388663968, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=30.6122448979592, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=31.7269076305221, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=30.8943089430894, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=32.824427480916, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4503301, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.9610894941634, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=31.6326530612245, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=28.030303030303, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=32.1951219512195, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=162, Percent_Identity=34.5679012345679, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226371731, Length=247, Percent_Identity=28.7449392712551, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI310128830, Length=211, Percent_Identity=27.4881516587678, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI310115468, Length=211, Percent_Identity=27.4881516587678, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI142976729, Length=206, Percent_Identity=27.6699029126214, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=31.2977099236641, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=41.4634146341463, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=36.4372469635627, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=37.5, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=34.2741935483871, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=31.5789473684211, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=34.9794238683128, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=32.0158102766798, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=32.6530612244898, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=33.1967213114754, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.5882352941176, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=31.1740890688259, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=31.2741312741313, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=33.8888888888889, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=39.0243902439024, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=36.9477911646586, Blast_Score=133, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=31.496062992126, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=30.6772908366534, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=33.8403041825095, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17536651, Length=267, Percent_Identity=31.8352059925094, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.4528301886792, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=32.6771653543307, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=31.3725490196078, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=29.5880149812734, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=218, Percent_Identity=29.3577981651376, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=29.3233082706767, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=261, Percent_Identity=34.8659003831418, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=221, Percent_Identity=28.5067873303167, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=30.188679245283, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=30.188679245283, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=29.3893129770992, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=31.2252964426877, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=30.188679245283, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.8507462686567, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=30.5882352941176, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.3893129770992, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=29.6153846153846, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=29.3233082706767, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=210, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=26.1992619926199, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.4090909090909, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=28.8389513108614, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.4090909090909, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.0936329588015, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=244, Percent_Identity=31.9672131147541, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=242, Percent_Identity=23.9669421487603, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=266, Percent_Identity=28.1954887218045, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=32.8042328042328, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=194, Percent_Identity=28.3505154639175, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=37.4501992031873, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=33.7448559670782, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=34.6613545816733, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=30.859375, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=30.2788844621514, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=31.7460317460317, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=32.5490196078431, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.3149606299213, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=32, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581726, Length=210, Percent_Identity=27.6190476190476, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649181, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281364892, Length=196, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI18859837, Length=257, Percent_Identity=29.5719844357977, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=28.2485875706215, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28522; Mature: 28522

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDHKKRPDLEKRPDLEKQSYPEKQSLSGKRALVTGAGQGIGAAIAEGLAATGAEVICTD
CCCCCCCCCCCCCCCCCHHCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEC
ISRERAAATAQALNAKGYNVRAEGLDVTDSAAIDALAAALPPLDVLVCNAGIVTHTPAEE
HHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCEEECCCHHH
MTDADWDKVIAVNLTGVFRTCRGFGRRMLEAGRGSIINIGSISGQIVNVPQPQCHYNASK
HCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCCCHH
AGVHHLTKSLAVEWATRGVRVNAVAPTYIETPLIQGLTSQPGRVSRWLDMTPMGRLGSPH
HHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHH
EIASVVQFLASEASSLLTGSIITADAGYTSI
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MNDHKKRPDLEKRPDLEKQSYPEKQSLSGKRALVTGAGQGIGAAIAEGLAATGAEVICTD
CCCCCCCCCCCCCCCCCHHCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEC
ISRERAAATAQALNAKGYNVRAEGLDVTDSAAIDALAAALPPLDVLVCNAGIVTHTPAEE
HHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCEEECCCHHH
MTDADWDKVIAVNLTGVFRTCRGFGRRMLEAGRGSIINIGSISGQIVNVPQPQCHYNASK
HCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCCCHH
AGVHHLTKSLAVEWATRGVRVNAVAPTYIETPLIQGLTSQPGRVSRWLDMTPMGRLGSPH
HHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHH
EIASVVQFLASEASSLLTGSIITADAGYTSI
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]