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The map label for this gene is aroD

Identifier: 15922609

GI number: 15922609

Start: 2285847

End: 2286497

Strand: Direct

Name: aroD

Synonym: ST2278

Alternate gene names: 15922609

Gene position: 2285847-2286497 (Clockwise)

Preceding gene: 15922608

Following gene: 15922611

Centisome position: 84.83

GC content: 30.41

Gene sequence:

>651_bases
ATGACTTTTGTTGTAGCATCTTTACCAATACGTAGTGAAAAGGATTTAGATAAAATTCCGCGATTATTAGATGCTGATTT
TGTTGAGCTAAGACTAGATTACTCCACTTCTCTTCCAGAAATACAAGTTATTGAGAAGTATAAAGATAGAATAATTGTGA
CTATAAGAGATGTAGATGAAGGAGGAATAAACAAAATAGACCCAGAAATAAAAGCGGAGTATTTAATAGAATTAAATAAG
AAAAATATACTATATGATGTTGAGGCTAAATTCGCTAAAAAATATAATATTCCGACTAGTAATAAAATTGTTTCAATACA
TTATCTAGATAGGGTTCCTTCTTACTCAGAAGTTTTTGAGTCACTAAGAGACTTCATAAAAGAAAGTTTTCTGTTAAAAG
TTGCTGTAATTGGAAAAGATGGATATAAAGAGCTTTTATCAAAACTTCTGGAACTCGAGAAAATAGCTGTAATGCCTATT
GGTGTTAATCCTTTAGAGAGAATAGCGTTTTCAATTTTGGGATCTAAACTGATTTATGGACATGCAGGCGAAGAAACAGC
TAAGGGTCAATTTCATTATAAAGTTGCTAAGCAAATACTAGATTATTTAACTTCAATCTCTATTTCGTCTCCTTCAATTT
TAACTGGATAA

Upstream 100 bases:

>100_bases
TTAAGTCTGGTGGTACAATTGAAAAAGCAGAATGTGTAAATAAGAGCAATCCAAATTTCTGGAAAGATTTAATTTCCTTA
AATGGGAGAATAATAATAAG

Downstream 100 bases:

>100_bases
AGTTTTATAGGATTTTTAGTTGCACCCTTTATAGCTCTTCCGTCTTTCAGAGAGAAATGAGTAAAATGGCACTGACATAT
AAGTTCTTCCCTTATTACTA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTFVVASLPIRSEKDLDKIPRLLDADFVELRLDYSTSLPEIQVIEKYKDRIIVTIRDVDEGGINKIDPEIKAEYLIELNK
KNILYDVEAKFAKKYNIPTSNKIVSIHYLDRVPSYSEVFESLRDFIKESFLLKVAVIGKDGYKELLSKLLELEKIAVMPI
GVNPLERIAFSILGSKLIYGHAGEETAKGQFHYKVAKQILDYLTSISISSPSILTG

Sequences:

>Translated_216_residues
MTFVVASLPIRSEKDLDKIPRLLDADFVELRLDYSTSLPEIQVIEKYKDRIIVTIRDVDEGGINKIDPEIKAEYLIELNK
KNILYDVEAKFAKKYNIPTSNKIVSIHYLDRVPSYSEVFESLRDFIKESFLLKVAVIGKDGYKELLSKLLELEKIAVMPI
GVNPLERIAFSILGSKLIYGHAGEETAKGQFHYKVAKQILDYLTSISISSPSILTG
>Mature_215_residues
TFVVASLPIRSEKDLDKIPRLLDADFVELRLDYSTSLPEIQVIEKYKDRIIVTIRDVDEGGINKIDPEIKAEYLIELNKK
NILYDVEAKFAKKYNIPTSNKIVSIHYLDRVPSYSEVFESLRDFIKESFLLKVAVIGKDGYKELLSKLLELEKIAVMPIG
VNPLERIAFSILGSKLIYGHAGEETAKGQFHYKVAKQILDYLTSISISSPSILTG

Specific function: Unknown

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_SULTO (Q96Y90)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378278.1
- ProteinModelPortal:   Q96Y90
- GeneID:   1460360
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2278
- NMPDR:   fig|273063.1.peg.2446
- HOGENOM:   HBG553407
- OMA:   ILYDVEA
- ProtClustDB:   PRK13576
- BioCyc:   STOK273063:ST2278-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00214
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 24498; Mature: 24367

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 107-107 ACT_SITE 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVVASLPIRSEKDLDKIPRLLDADFVELRLDYSTSLPEIQVIEKYKDRIIVTIRDVDE
CEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEEEECCC
GGINKIDPEIKAEYLIELNKKNILYDVEAKFAKKYNIPTSNKIVSIHYLDRVPSYSEVFE
CCCCCCCHHHHHEEEEEECCCCEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
SLRDFIKESFLLKVAVIGKDGYKELLSKLLELEKIAVMPIGVNPLERIAFSILGSKLIYG
HHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHEEC
HAGEETAKGQFHYKVAKQILDYLTSISISSPSILTG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TFVVASLPIRSEKDLDKIPRLLDADFVELRLDYSTSLPEIQVIEKYKDRIIVTIRDVDE
EEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEEEECCC
GGINKIDPEIKAEYLIELNKKNILYDVEAKFAKKYNIPTSNKIVSIHYLDRVPSYSEVFE
CCCCCCCHHHHHEEEEEECCCCEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
SLRDFIKESFLLKVAVIGKDGYKELLSKLLELEKIAVMPIGVNPLERIAFSILGSKLIYG
HHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHEEC
HAGEETAKGQFHYKVAKQILDYLTSISISSPSILTG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479