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The map label for this gene is aroA

Identifier: 15922608

GI number: 15922608

Start: 2284624

End: 2285850

Strand: Direct

Name: aroA

Synonym: ST2277

Alternate gene names: 15922608

Gene position: 2284624-2285850 (Clockwise)

Preceding gene: 15922607

Following gene: 15922609

Centisome position: 84.78

GC content: 31.95

Gene sequence:

>1227_bases
ATGTTAGTAGAGATTAATCCTTCAAAAATTTATGGGAAAGTTAAAGCCCCTCAGTCAAAAAGTTTTGGAATAAGACTAGT
TCTATATTCATTATTAAAAGAAAGTAAGCTAGACAACTTAATACCTTCTGATGACGTTAATGTGGCTATTAATGTTGTTA
AACAGCTAGGAGTTAGTGTTGAAGGCACTTACTTTAAGAGGGAAAAAGAGCTTGTAACCCCAAAATTTTTGTATTTCGGT
GGTTCTGCAACGACATTAAGGATGAGTATACCAATACTTTCTGTTTTAGGTGTGGATACAATAATCGATGGAGATGAAAC
TTTGAGAAAAAGACCATTAAATGCTATTATTAAGGCATTAGAGGGTAGTGTTTCTTTTTCTTCGTCATTACTTCCGACAA
AAATTAGTGGAAAGCTTAAGGAGAATTTTGTACGAATAGAAGGTGGAGAAAGTAGTCAATACATATCTGGATTCATCTAT
GCTTTTTCATTAGTAGGTGGTGGAGAAATAGAAATAATTCCACCTATATCCTCTAAGAGTTATATTTATCTCACAATCGA
ATTATTAAATAGTCTAGGCGGAAATATAAAAATGAAAGGAAATAAAATATACGTTGAAAAGGGAGATTTCAAACCTTATA
TAGGTAAAGTTCCAGGAGATTATGCTTTAGCTTCATTTTATGCTTCCTCCAGTATAGTTTCAGGAGGGGAAATTGTAATC
GAGGACGTTTATGAGTTACCTAATTTTGATGGAGATCATTCTATAGTTAATTTTTATAAGATGATGGGGGCAGAATCTTA
TGTTAAAGATAATAAATGGATTGTAAAGAGTAGTGAAAAGCTAAACGGTATTGAGGTCAATGTTGATGATTATCCCGATT
TAGCTCCTTCTATTGCATCATTAGCTCCTTTTTCTTCTTCACCTACAATTATAAAGGGTATAAAGAGACTTAAGACAAAG
GAAAGTAATAGAGTTGTAACTATTTCAGAAACATTATCAAAATTTGGAGTAAAGGTAGAATATGATGAGGACAAAATCGT
TATTTATCCTTCTGAAGTTAAAGCTGGTCATGTAATTTGTCCTAATGATCATAGGATAGCAATGTTAGCATCAGTTTTAT
CTTTTAAGTCTGGTGGTACAATTGAAAAAGCAGAATGTGTAAATAAGAGCAATCCAAATTTCTGGAAAGATTTAATTTCC
TTAAATGGGAGAATAATAATAAGATGA

Upstream 100 bases:

>100_bases
GGTCCTTCAATATTTGCGGTAACAAAAATAGGTGAAGAAGGACCTATTGTAGACGCTTTATCAAAATTCGGAAACGTAAT
TGTAACGAGGTCTGTAGGGT

Downstream 100 bases:

>100_bases
CTTTTGTTGTAGCATCTTTACCAATACGTAGTGAAAAGGATTTAGATAAAATTCCGCGATTATTAGATGCTGATTTTGTT
GAGCTAAGACTAGATTACTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MLVEINPSKIYGKVKAPQSKSFGIRLVLYSLLKESKLDNLIPSDDVNVAINVVKQLGVSVEGTYFKREKELVTPKFLYFG
GSATTLRMSIPILSVLGVDTIIDGDETLRKRPLNAIIKALEGSVSFSSSLLPTKISGKLKENFVRIEGGESSQYISGFIY
AFSLVGGGEIEIIPPISSKSYIYLTIELLNSLGGNIKMKGNKIYVEKGDFKPYIGKVPGDYALASFYASSSIVSGGEIVI
EDVYELPNFDGDHSIVNFYKMMGAESYVKDNKWIVKSSEKLNGIEVNVDDYPDLAPSIASLAPFSSSPTIIKGIKRLKTK
ESNRVVTISETLSKFGVKVEYDEDKIVIYPSEVKAGHVICPNDHRIAMLASVLSFKSGGTIEKAECVNKSNPNFWKDLIS
LNGRIIIR

Sequences:

>Translated_408_residues
MLVEINPSKIYGKVKAPQSKSFGIRLVLYSLLKESKLDNLIPSDDVNVAINVVKQLGVSVEGTYFKREKELVTPKFLYFG
GSATTLRMSIPILSVLGVDTIIDGDETLRKRPLNAIIKALEGSVSFSSSLLPTKISGKLKENFVRIEGGESSQYISGFIY
AFSLVGGGEIEIIPPISSKSYIYLTIELLNSLGGNIKMKGNKIYVEKGDFKPYIGKVPGDYALASFYASSSIVSGGEIVI
EDVYELPNFDGDHSIVNFYKMMGAESYVKDNKWIVKSSEKLNGIEVNVDDYPDLAPSIASLAPFSSSPTIIKGIKRLKTK
ESNRVVTISETLSKFGVKVEYDEDKIVIYPSEVKAGHVICPNDHRIAMLASVLSFKSGGTIEKAECVNKSNPNFWKDLIS
LNGRIIIR
>Mature_408_residues
MLVEINPSKIYGKVKAPQSKSFGIRLVLYSLLKESKLDNLIPSDDVNVAINVVKQLGVSVEGTYFKREKELVTPKFLYFG
GSATTLRMSIPILSVLGVDTIIDGDETLRKRPLNAIIKALEGSVSFSSSLLPTKISGKLKENFVRIEGGESSQYISGFIY
AFSLVGGGEIEIIPPISSKSYIYLTIELLNSLGGNIKMKGNKIYVEKGDFKPYIGKVPGDYALASFYASSSIVSGGEIVI
EDVYELPNFDGDHSIVNFYKMMGAESYVKDNKWIVKSSEKLNGIEVNVDDYPDLAPSIASLAPFSSSPTIIKGIKRLKTK
ESNRVVTISETLSKFGVKVEYDEDKIVIYPSEVKAGHVICPNDHRIAMLASVLSFKSGGTIEKAECVNKSNPNFWKDLIS
LNGRIIIR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=413, Percent_Identity=26.1501210653753, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_SULTO (Q96Y91)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378277.1
- ProteinModelPortal:   Q96Y91
- GeneID:   1460359
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2277
- NMPDR:   fig|273063.1.peg.2445
- HOGENOM:   HBG646626
- OMA:   SSQFITS
- ProtClustDB:   PRK02427
- BioCyc:   STOK273063:ST2277-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 44797; Mature: 44797

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVEINPSKIYGKVKAPQSKSFGIRLVLYSLLKESKLDNLIPSDDVNVAINVVKQLGVSV
CEEEECHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
EGTYFKREKELVTPKFLYFGGSATTLRMSIPILSVLGVDTIIDGDETLRKRPLNAIIKAL
CCEEEECCHHCCCCEEEEECCCCEEEEEECCHHHHHCCCEEECCHHHHHHCCHHHHHHHH
EGSVSFSSSLLPTKISGKLKENFVRIEGGESSQYISGFIYAFSLVGGGEIEIIPPISSKS
CCCCCCCCCCCCCHHCCCHHHCEEEEECCCCCHHHHHEEEEEEEECCCEEEEECCCCCCC
YIYLTIELLNSLGGNIKMKGNKIYVEKGDFKPYIGKVPGDYALASFYASSSIVSGGEIVI
EEEEEHHHHHHHCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEE
EDVYELPNFDGDHSIVNFYKMMGAESYVKDNKWIVKSSEKLNGIEVNVDDYPDLAPSIAS
EEHHHCCCCCCCHHHHHHHHHHCCHHHHCCCEEEEECCCCCCCEEEECCCCCCCCHHHHH
LAPFSSSPTIIKGIKRLKTKESNRVVTISETLSKFGVKVEYDEDKIVIYPSEVKAGHVIC
HCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEC
PNDHRIAMLASVLSFKSGGTIEKAECVNKSNPNFWKDLISLNGRIIIR
CCCCHHHHHHHHHHHCCCCCEEHHHHCCCCCCHHHHHHHHCCCEEEEC
>Mature Secondary Structure
MLVEINPSKIYGKVKAPQSKSFGIRLVLYSLLKESKLDNLIPSDDVNVAINVVKQLGVSV
CEEEECHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
EGTYFKREKELVTPKFLYFGGSATTLRMSIPILSVLGVDTIIDGDETLRKRPLNAIIKAL
CCEEEECCHHCCCCEEEEECCCCEEEEEECCHHHHHCCCEEECCHHHHHHCCHHHHHHHH
EGSVSFSSSLLPTKISGKLKENFVRIEGGESSQYISGFIYAFSLVGGGEIEIIPPISSKS
CCCCCCCCCCCCCHHCCCHHHCEEEEECCCCCHHHHHEEEEEEEECCCEEEEECCCCCCC
YIYLTIELLNSLGGNIKMKGNKIYVEKGDFKPYIGKVPGDYALASFYASSSIVSGGEIVI
EEEEEHHHHHHHCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEE
EDVYELPNFDGDHSIVNFYKMMGAESYVKDNKWIVKSSEKLNGIEVNVDDYPDLAPSIAS
EEHHHCCCCCCCHHHHHHHHHHCCHHHHCCCEEEEECCCCCCCEEEECCCCCCCCHHHHH
LAPFSSSPTIIKGIKRLKTKESNRVVTISETLSKFGVKVEYDEDKIVIYPSEVKAGHVIC
HCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEC
PNDHRIAMLASVLSFKSGGTIEKAECVNKSNPNFWKDLISLNGRIIIR
CCCCHHHHHHHHHHHCCCCCEEHHHHCCCCCCHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479